MELISSA ANN DESTEFANO PA-C
NPI 1265461313
Physician Assistant - Medical in Lancaster, PA

Q: What is Melissa Destefano's NPI number?

The NPI number for Melissa Destefano is 1265461313. It was assigned to this individual provider in the NPPES registry on July 1, 2006.

Q: What is Melissa Destefano's specialty?

The primary specialty registered for this NPI is Physician Assistant, specializing in Medical, with taxonomy code 363AM0700X.

Q: When was this NPI record last updated?

The NPPES record for Melissa Destefano was last updated on September 18, 2025. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 10 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.

Active since July 01, 2006PECOS EnrolledAccepts Medicare Assignment

2150 HARRISBURG PIKE, STE 200A, LANCASTER, PA 17601(717) 396-9167(717) 396-9064 Get Directions Write a Review

NPPES record last updated: September 18, 2025. Verified against the NPPES registry weekly; last sync: August 02, 2026.

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About Melissa Ann Destefano Pa-c NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

MELISSA ANN DESTEFANO PA-C (NPI 1265461313) is an individual medical provider in Lancaster, Pennsylvania, licensed in Pennsylvania (MA053304) and active in the NPI registry since July 2006. She is enrolled in Medicare PECOS, is affiliated with Lancaster General Hospital, and is a graduate of Other (2004).

NPPES Registry Identity

NPI1265461313

Entity TypeIndividualFemale

Primary Taxonomy363AM0700X

Provider Legal NameMELISSA ANN DESTEFANOCredential: PA-C

Location Address2150 HARRISBURG PIKE, STE 200ALancaster, PA 17601-2644

Mailing Address2150 Harrisburg Pike, Ste 200aLancaster, PA 17601-2644 · (717) 396-9167 · Fax (717) 396-9064

Phone(717) 396-9167

Fax(717) 396-9064

Sole ProprietorNo

Medical School CMSOtherGraduated 2004

Enumeration DateJuly 1, 2006

Last NPPES UpdateSeptember 18, 2025

NPPES CertifiedSeptember 18, 2025

✔ NPI 1265461313 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyPhysician Assistant · MedicalPhysician Assistants & Advanced Practice Nursing Providers

Taxonomy Code363AM0700X

License✔ Licensed in PA · MA053304

2150 HARRISBURG PIKE, Lancaster, PA 17601

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Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Ambetter from Buckeye Health Plan, Ambetter Health, Ambetter Health of Delaware.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, and ordering and referring status from the CMS PECOS system.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Melissa Ann Destefano Pa-c is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID6709834344

PECOS Enrollment IDI20080605000120

Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Areas of Expertise CMS Part B claims 5

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214

This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.

123 services92 patients

Established patient office or other outpatient visit with high level of medical decision making, if using time, 40 minutes or more 99215

This service involves a follow-up appointment for existing patients, lasting between 40 to 54 minutes. During this time, your healthcare provider will assess your current health status, discuss any changes or concerns, review your treatment plan, and answer any questions you may have.

74 services58 patients

New patient office or other outpatient visit with a high level of medical decision making, if using time, 60 minutes or more 99205

This is a first-time patient visit where a healthcare professional spends 60-74 minutes with you. It involves a comprehensive evaluation, including your medical history and current health condition. They'll also advise on preventive health measures and formulate a treatment plan if needed.

56 services56 patients

Established patient office or other outpatient visit with low level od decision making, if using time, 20 minutes or more 99213

This is a routine visit for patients who have already been seen by the healthcare provider. During this approximately 20-29 minute appointment, your health status will be evaluated and any necessary treatments or tests will be discussed. It's a chance to address any health concerns you may have.

49 services39 patients

New patient office or other outpatient visit with moderate level of medical decision making, if using time, 45 minutes or more 99204

This is a first-time office or outpatient visit lasting between 45-59 minutes. The healthcare provider evaluates your health, discusses your medical history, and may suggest further tests or treatments. It's an opportunity to ask questions and understand your health better.

19 services19 patients

Hospital Affiliations CMS Care Compare

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Lancaster General Hospital

Acute Care Hospitals · Lancaster, PA

5/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number390100

Location555 North Duke StreetLancaster, PA 17602 · Lancaster County

Emergency services Birthing friendly

Referred Medical Equipment & Supplies CMS DME claims 3

Durable medical equipment, devices and supplies this provider ordered from DME suppliers for patients, from Medicare fee-for-service claims.

Blood glucose test or reagent strips for home blood glucose monitor, per 50 strips A4253

DME-Other DME · category DE017N

6 suppliers16 claims42 services$4.58 avg. paid by Medicare

Face mask interface, replacement for full face mask, each A7031

DME-Other DME · category DE001N

1 supplier13 claims13 services$29.95 avg. paid by Medicare

Filter, disposable, used with positive airway pressure device A7038

DME-Other DME · category DE001N

1 supplier15 claims30 services$1.97 avg. paid by Medicare

Dollar amounts are the average Medicare paid the supplier per service. They are not the cost to the patient.

Other Providers at the Same Location NPPES 20

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

THOMAS RUSSELL WESTPHAL M.D.

Orthopaedic Surgery

2150 HARRISBURG PIKE, SUITE 200
LANCASTER, PA 17601

Lancaster County (717) 358-0800

DINA Y. GEWAILY MD

Ophthalmology

2150 HARRISBURG PIKE, STE 370
LANCASTER, PA 17601

Lancaster County (717) 399-8790

ALLISON M CROWELL MD

Psychiatry & Neurology (Neurology)

2150 HARRISBURG PIKE, STE 200A
LANCASTER, PA 17601

Lancaster County (717) 396-9167

LANCASTER GENERAL HOSPITAL

Internal Medicine (Obesity Medicine)

2150 HARRISBURG PIKE, SUITE 300
LANCASTER, PA 17601

Lancaster County (717) 544-2935

RYAN SERBEL DPT

Physical Therapist

2150 HARRISBURG PIKE, SUITE
LANCASTER, PA 17601

Lancaster County (717) 358-0800

JESSICA YOUNG PSYD

Psychologist (Clinical)

2150 HARRISBURG PIKE
LANCASTER, PA 17601

Lancaster County (717) 544-3170

WEN YING HELENA WU-CHEN M.D.

Psychiatry & Neurology (Neurology)

2150 HARRISBURG PIKE, STE 200A
LANCASTER, PA 17601

Lancaster County (717) 396-9167

SAVANNAH GREINER RD

Dietitian, Registered

2150 HARRISBURG PIKE
LANCASTER, PA 17601

Lancaster County (717) 544-2935

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Melissa Destefano's NPI number?

The NPI number for Melissa Destefano is 1265461313. It was assigned to this individual provider in the NPPES registry on July 1, 2006.

Where is Melissa Destefano located?

Melissa Destefano practices at 2150 Harrisburg Pike Ste 200A, Lancaster, PA 17601. The listed phone number is (717) 396-9167.

What is Melissa Destefano's specialty?

The primary specialty registered for this NPI is Physician Assistant, specializing in Medical, with taxonomy code 363AM0700X.

Is Melissa Destefano enrolled in Medicare?

Yes. Melissa Destefano is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

What insurance does Melissa Destefano accept?

Health plans from Ambetter Health, Ambetter Health of Delaware and Ambetter from Buckeye Health Plan list Melissa Destefano as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Melissa Destefano affiliated with any hospitals?

According to CMS data, Melissa Destefano is affiliated with Lancaster General Hospital.

When was this NPI record last updated?

The NPPES record for Melissa Destefano was last updated on September 18, 2025. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 10 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.