MRS. NATALIE MAIN FNP-C
Prescription History 1922700970
Nurse Practitioner - Family in Muncie, IN
What does Natalie Main prescribe?
In 2024, Natalie Main wrote 2,953 Medicare prescriptions for 35 medications. The most prescribed was Hydroxychloroquine Sulfate, with 393 prescriptions for 147 patients.
Medicare Part D only. These are prescriptions filled by people with Medicare drug coverage in 2024, from the CMS data released in 2026, the most recent year available. CMS does not publish medications with fewer than 11 prescriptions, so this is not a full list of what Natalie Main prescribes.
Medications 35 medications
Prescriptions filled under Medicare Part D in 2024. Select a medication to see what it is used for and how it compares with other Indiana prescribers.
What it is used for
Hydroxychloroquine is used to prevent or treat malaria caused by mosquito bites.
Compared with Indiana prescribers
Natalie Main wrote 393 prescriptions for Hydroxychloroquine Sulfate, about 4.4 times as often as the typical Indiana prescriber of it (89). Medicare paid $37.27 per fill, versus $33.87 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Prednisone is used to treat conditions such as arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders.
Compared with Indiana prescribers
Natalie Main wrote 367 prescriptions for Prednisone, about 7.6 times as often as the typical Indiana prescriber of it (49). Medicare paid $5.63 per fill, versus $3.47 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Methotrexate is used to treat certain types of cancer (such as acute lymphoblastic leukemia, non-Hodgkin's lymphoma), severe psoriasis that has not responded to other treatments, or rheumatoid arthritis.
Compared with Indiana prescribers
Natalie Main wrote 350 prescriptions for Methotrexate, about 3.4 times as often as the typical Indiana prescriber of it (103). Medicare paid $30.94 per fill, versus $22.02 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This combination medication is used to relieve moderate to severe pain.
Compared with Indiana prescribers
Natalie Main wrote 250 prescriptions for Hydrocodone-Acetaminophen, about 2.6 times as often as the typical Indiana prescriber of it (97). Medicare paid $16.72 per fill, versus $19.01 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat rheumatoid arthritis, a condition in which the body's defense system (immune system) fails to recognize the body as itself and attacks the healthy tissues around the joints.
Compared with Indiana prescribers
Natalie Main wrote 181 prescriptions for Leflunomide, about 2.2 times as often as the typical Indiana prescriber of it (81). Medicare paid $59.96 per fill, versus $60.66 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
See also Warning section.
Compared with Indiana prescribers
Natalie Main wrote 130 prescriptions for Tramadol Hcl, about 2.2 times as often as the typical Indiana prescriber of it (59). Medicare paid $8.26 per fill, versus $7.63 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Methylprednisolone is used to treat conditions such as arthritis, blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/kidney/intestinal/lung diseases, and immune system disorders.
Compared with Indiana prescribers
Natalie Main wrote 126 prescriptions for Methylprednisolone, about 3.6 times as often as the typical Indiana prescriber of it (35). Medicare paid $7.38 per fill, versus $6.35 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Gabapentin is used with other medications to prevent and control seizures.
Compared with Indiana prescribers
Natalie Main wrote 118 prescriptions for Gabapentin, about as often as the typical Indiana prescriber of it (110). Medicare paid $13.11 per fill, versus $14.41 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat pain caused by nerve damage due to diabetes, shingles (herpes zoster) infection, or spinal cord injury.
Compared with Indiana prescribers
Natalie Main wrote 101 prescriptions for Pregabalin, about 2 times as often as the typical Indiana prescriber of it (52). Medicare paid $36.52 per fill, versus $31.21 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury).
Compared with Indiana prescribers
Natalie Main wrote 101 prescriptions for Tizanidine Hcl, about 2.1 times as often as the typical Indiana prescriber of it (47). Medicare paid $9.68 per fill, versus $11.88 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Meloxicam is used to treat arthritis.
Compared with Indiana prescribers
Natalie Main wrote 71 prescriptions for Meloxicam, about 1.2 times as often as the typical Indiana prescriber of it (58). Medicare paid $2.09 per fill, versus $3.89 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Upadacitinib is used to treat certain types of arthritis (such as psoriatic arthritis, rheumatoid arthritis, axial spondyloarthritis, polyarticular juvenile idiopathic arthritis- pJIA).
Compared with Indiana prescribers
Natalie Main wrote 61 prescriptions for Rinvoq, about 1.9 times as often as the typical Indiana prescriber of it (33). Medicare paid $6,242.41 per fill, versus $6,797.02 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Cyclobenzaprine is used short-term to treat muscle spasms.
Compared with Indiana prescribers
Natalie Main wrote 58 prescriptions for Cyclobenzaprine Hcl, about 1.4 times as often as the typical Indiana prescriber of it (42). Medicare paid $8.33 per fill, versus $8.95 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This combination medication is used to help relieve moderate to severe pain.
Compared with Indiana prescribers
Natalie Main wrote 55 prescriptions for Oxycodone-Acetaminophen, about 66% as often as the typical Indiana prescriber of it (83). Medicare paid $16.90 per fill, versus $24.92 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is a nonsteroidal anti-inflammatory drug (NSAID), specifically a COX-2 inhibitor, which relieves pain and swelling (inflammation).
Compared with Indiana prescribers
Natalie Main wrote 54 prescriptions for Celecoxib, about 1.4 times as often as the typical Indiana prescriber of it (37). Medicare paid $33.43 per fill, versus $37.68 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat certain mental/mood disorders (such as depression, anxiety).
Compared with Indiana prescribers
Natalie Main wrote 54 prescriptions for Duloxetine Hcl, about 86% as often as the typical Indiana prescriber of it (63). Medicare paid $16.46 per fill, versus $23.69 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Baclofen is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury/disease).
Compared with Indiana prescribers
Natalie Main wrote 52 prescriptions for Baclofen, about 1.2 times as often as the typical Indiana prescriber of it (43). Medicare paid $15.27 per fill, versus $19.94 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Sulfasalazine is used to treat a certain type of bowel disease called ulcerative colitis.
Compared with Indiana prescribers
Natalie Main wrote 49 prescriptions for Sulfasalazine, about 1.4 times as often as the typical Indiana prescriber of it (35). Medicare paid $17.59 per fill, versus $24.58 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Folic acid is the man-made form of folate.
Compared with Indiana prescribers
Natalie Main wrote 44 prescriptions for Folic Acid, about 1.5 times as often as the typical Indiana prescriber of it (29). Medicare paid $13.32 per fill, versus $7.99 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to reduce pain and swelling due to certain inflammatory conditions (such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, polyarticular juvenile idiopathic arthritis).
Compared with Indiana prescribers
Natalie Main wrote 38 prescriptions for Cimzia (2 Pack), about 1.8 times as often as the typical Indiana prescriber of it (21). Medicare paid $5,630.03 per fill, versus $6,343.48 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat rheumatoid arthritis, a condition in which the body's own defense system (immune system) attacks healthy tissue.
Compared with Indiana prescribers
Natalie Main wrote 35 prescriptions for Orencia Clickject, about as often as the typical Indiana prescriber of it (34). Medicare paid $5,787.80 per fill, versus $5,972.94 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Allopurinol is used to treat gout and certain types of kidney stones.
Compared with Indiana prescribers
Natalie Main wrote 32 prescriptions for Allopurinol, about half as often as the typical Indiana prescriber of it (57). Medicare paid $8.13 per fill, versus $8.17 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
See also Warning section.
Compared with Indiana prescribers
Natalie Main wrote 31 prescriptions for Diclofenac Sodium, about 83% as often as the typical Indiana prescriber of it (37). Medicare paid $46.90 per fill, versus $23.54 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Adalimumab is used to reduce pain and swelling due to certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, ankylosing spondylitis).
Compared with Indiana prescribers
Natalie Main wrote 30 prescriptions for Humira(Cf) Pen, about 74% as often as the typical Indiana prescriber of it (40). Medicare paid $7,110.31 per fill, versus $8,629.43 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat plaque psoriasis and certain types of arthritis (such as arthritis of the spine, psoriatic arthritis, axial spondyloarthritis, enthesitis-related arthritis).
Compared with Indiana prescribers
Natalie Main wrote 25 prescriptions for Cosentyx Sensoready (2 Pens), about as often as the typical Indiana prescriber of it (23). Medicare paid $7,735.22 per fill, versus $7,970.31 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis).
Compared with Indiana prescribers
Natalie Main wrote 20 prescriptions for Enbrel Sureclick, about 34% as often as the typical Indiana prescriber of it (59). Medicare paid $7,469.79 per fill, versus $7,793.49 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat a certain type of arthritis (psoriatic arthritis).
Compared with Indiana prescribers
Natalie Main wrote 18 prescriptions for Otezla, about 74% as often as the typical Indiana prescriber of it (24). Medicare paid $4,839.88 per fill, versus $4,777.48 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat symptoms of dry mouth due to a certain immune disease (Sjogren's syndrome) or from saliva gland damage due to radiation treatments of the head/neck for cancer.
Compared with Indiana prescribers
Natalie Main wrote 17 prescriptions for Pilocarpine Hcl, about 79% as often as the typical Indiana prescriber of it (22). Medicare paid $94.89 per fill, versus $73.41 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used alone or with other medications to treat Parkinson's disease.
Compared with Indiana prescribers
Natalie Main wrote 16 prescriptions for Ropinirole Hcl, about half as often as the typical Indiana prescriber of it (38). Medicare paid $9.48 per fill, versus $16.10 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Tofacitinib is used to treat certain types of arthritis (such as psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis).
Compared with Indiana prescribers
Natalie Main wrote 16 prescriptions for Xeljanz Xr, about 63% as often as the typical Indiana prescriber of it (26). Medicare paid $8,429.78 per fill, versus $6,345.45 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to help relieve severe ongoing pain (such as due to cancer).
Compared with Indiana prescribers
Natalie Main wrote 13 prescriptions for Fentanyl, about 42% as often as the typical Indiana prescriber of it (31). Medicare paid $188.84 per fill, versus $117.28 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Alendronate is used to prevent and treat certain types of bone loss (osteoporosis) in adults.
Compared with Indiana prescribers
Natalie Main wrote 12 prescriptions for Alendronate Sodium, about 23% as often as the typical Indiana prescriber of it (53). Medicare paid $7.24 per fill, versus $7.32 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Methocarbamol is used to treat muscle spasms/pain.
Compared with Indiana prescribers
Natalie Main wrote 12 prescriptions for Methocarbamol, about 39% as often as the typical Indiana prescriber of it (31). Medicare paid $7.29 per fill, versus $11.11 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to reduce pain and swelling due to certain types of arthritis (such as rheumatoid, psoriatic, and ankylosing spondylitis).
Compared with Indiana prescribers
Natalie Main wrote 12 prescriptions for Simponi, about 62% as often as the typical Indiana prescriber of it (19). Medicare paid $6,112.99 per fill, versus $6,493.60 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used with other medications to treat certain types of lupus.
Compared with Indiana prescribers
Natalie Main wrote 11 prescriptions for Benlysta, about half as often as the typical Indiana prescriber of it (21). Medicare paid $5,089.90 per fill, versus $4,909.79 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
Questions about Natalie Main’s prescriptions
What does Natalie Main prescribe most?
In 2024 Medicare Part D data, Natalie Main's most prescribed medications were Hydroxychloroquine Sulfate (393), Prednisone (367) and Methotrexate (350).
How does Natalie Main's prescribing compare with other Indiana prescribers?
Of the 35 medications with a state comparison, Natalie Main prescribes 15 more often than the typical Indiana prescriber, 8 about as often and 12 less often. Volume reflects practice size as well as prescribing habits.
Does this list show every medication Natalie Main prescribes?
No. It covers prescriptions filled by people with Medicare Part D drug coverage in 2024, and CMS leaves out any medication with fewer than 11 prescriptions.
About this data
This page shows one provider’s slice of public Medicare files. NPI Profile does not receive prescriptions or patient records.
| Source | What it provides here | Data year |
|---|---|---|
| CMS Medicare Part D Prescribers by Provider and Drug | Each medication, prescriptions, patients, 30-day fills, days of medication and cost. State comparisons average the Indiana prescribers of the same medication and form, where at least five wrote it. | 2024 (released 2026, the most recent available) |
| CMS Medicare Part D Drug Spending Dashboard | What each medication is used for. | 2024 |
- Only prescriptions filled by people with Medicare Part D drug coverage are counted. Private insurance, Medicaid and cash purchases are not.
- CMS leaves out medications with fewer than 11 prescriptions and hides patient counts under 11.
- Cost per fill is what the plan and the patient paid the pharmacy together, not what you pay at the counter.
- Medication descriptions are summaries from CMS. They are not medical advice; ask a health care professional about any medication.