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SANTIAGO MANUEL CAYETANO LOPEZ M.D.
NPI 1922351246
Pediatrics - Pediatric Infectious Diseases in Sioux Falls, SD

Active since October 24, 2012PECOS Enrolled
1600 W 22ND ST, SIOUX FALLS, SD 57105(605) 312-1000(605) 312-1001 Get Directions Write a Review

NPPES record last updated: April 5, 2019. Verified against the NPPES registry weekly; last sync: October 25, 2026.

About Santiago Manuel Cayetano Lopez M.d. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

SANTIAGO MANUEL CAYETANO LOPEZ M.D. (NPI 1922351246) is an individual pediatric infectious diseases provider in Sioux Falls, South Dakota, licensed in South Dakota (10963) and active in the NPI registry since October 2012. He is enrolled in Medicare PECOS.

NPPES Registry Identity

NPI1922351246
Entity TypeIndividualMale
Primary Taxonomy2080P0208X
Provider Legal NameSANTIAGO MANUEL CAYETANO LOPEZCredential: M.D.
Location Address1600 W 22ND STSioux Falls, SD 57105-1521
Mailing Address700 Childrens DrColumbus, OH 43205-2664 · (614) 722-4411 · Fax (614) 722-6132
Phone(605) 312-1000
Fax(605) 312-1001
Sole ProprietorNo
Enumeration DateOctober 24, 2012
Last NPPES UpdateApril 5, 2019
✔ NPI 1922351246 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyPediatrics · Pediatric Infectious DiseasesAllopathic & Osteopathic Physicians
Taxonomy Code2080P0208X
License✔ Licensed in SD · 10963
Definition
A pediatrician trained to care for children in the diagnosis, treatment and prevention of infectious diseases. This specialist can apply specific knowledge to affect a better outcome for pediatric infections with complicated courses, underlying diseases that predispose to unusual or severe infections, unclear diagnoses, uncommon diseases and complex or investigational treatments.
1600 W 22ND ST, Sioux Falls, SD 57105
Open in Google Maps ↗

Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Sanford Health Plan, Security Health Plan, Wellmark Health Plan of Iowa, Inc. and more.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare (PECOS)

Santiago Manuel Cayetano Lopez M.d. is registered in the CMS Provider Enrollment, Chain and Ownership System (PECOS).

Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

2

Medicare enrollment records show Santiago Lopez reassigns Medicare billing to 2 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Sanford Clinic
Same address
Pediatrics
1600 W 22ND ST
Sioux Falls, SD 57105
  • Reassigned Medicare billing, South Dakota enrollment
  • 826 clinicians in this Medicare group
NPI 1881610889 (605) 312-1000
Sanford Medical Center
0.8 mi
Family Medicine
1420 W 22NDST STE 104
Sioux Falls, SD 57105
  • Reassigned Medicare billing, South Dakota enrollment
  • 1,097 clinicians in this Medicare group
NPI 1093090342 (605) 328-4897

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Other Providers at the Same Location NPPES 20

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

JANELLE VANDE GRIEND APRN-CPNP
Nurse Practitioner
1600 W 22ND ST
SIOUX FALLS, SD 57105
Minnehaha County (605) 312-1000
KAILEN K KRAUSE
Registered Nurse (Pediatrics)
1600 W 22ND ST
SIOUX FALLS, SD 57105
Minnehaha County (605) 312-1000
AMANDA CHARLENE NOONAN DNP
Nurse Practitioner (Psychiatric/Mental Health)
1600 W 22ND ST
SIOUX FALLS, SD 57105
Minnehaha County (605) 328-6585
KAYELYN J. WAGNER M.D.
Pediatrics (Pediatric Hematology-Oncology)
1600 W 22ND ST
SIOUX FALLS, SD 57105
Minnehaha County (605) 312-1000
AMBER JENAE VELDMAN MD
Pediatrics
1600 W 22ND ST
SIOUX FALLS, SD 57105
Minnehaha County (605) 312-1000
SYED HARIS ZAMIR KAZMI MD
Pediatrics
1600 W 22ND ST
SIOUX FALLS, SD 57105
Minnehaha County (605) 312-1000
MRS. MORGAN DOLORES COLLINS RN, CDCES
Registered Nurse (Diabetes Educator)
1600 W 22ND ST
SIOUX FALLS, SD 57105
Minnehaha County (605) 312-1000
CHARLES A BROBERG DC, PA,
Physician Assistant
1600 W 22ND ST
SIOUX FALLS, SD 57105
Minnehaha County (605) 312-1000

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Santiago Lopez's NPI number?

The NPI number for Santiago Lopez is 1922351246. It was assigned to this individual provider in the NPPES registry on October 24, 2012.

Where is Santiago Lopez located?

Santiago Lopez practices at 1600 W 22nd St, Sioux Falls, SD 57105. The listed phone number is (605) 312-1000.

What is Santiago Lopez's specialty?

The primary specialty registered for this NPI is Pediatrics, specializing in Pediatric Infectious Diseases, with taxonomy code 2080P0208X.

Is Santiago Lopez enrolled in Medicare?

Yes. Santiago Lopez is registered in the Medicare PECOS enrollment system.

Which organizations bill Medicare for Santiago Lopez's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Santiago Lopez reassigns Medicare benefits to 2 organizations: Sanford Clinic (Sioux Falls, SD) and Sanford Medical Center (Sioux Falls, SD). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Santiago Lopez's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

What insurance does Santiago Lopez accept?

Health plans from Sanford Health Plan, Security Health Plan, Wellmark Health Plan of Iowa, Inc. and Wellmark of South Dakota, Inc. list Santiago Lopez as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

When was this NPI record last updated?

The NPPES record for Santiago Lopez was last updated on April 5, 2019. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 7 years ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.