Recently Updated NPI Information — some details in this NPI profile have been updated in the NPI registry within the last 60 days.

DR. MATTHEW J KARPENKO DO
NPI 1912118647
Internal Medicine - Hematology & Oncology in Salisbury, MD

Active since May 24, 2007PECOS EnrolledAccepts Medicare Assignment
100 E CARROLL ST, SALISBURY, MD 21801(410) 546-6400 Get Directions Write a Review

NPPES record last updated: August 14, 2026. Verified against the NPPES registry weekly; last sync: August 16, 2026.

Record update history: Aug 14, 2026, Jul 27, 2021, Jul 2, 2019 and 1 more (4 updates tracked since 2016).

About Dr. Matthew J Karpenko Do NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

DR. MATTHEW J KARPENKO DO (NPI 1912118647) is an individual hematology & oncology provider in Salisbury, Maryland, licensed in North Carolina (2010-01037) and active in the NPI registry since May 2007. He is enrolled in Medicare PECOS, is affiliated with Cape Fear Valley Medical Center, and maintains 5 additional practice locations.

NPPES Registry Identity

NPI1912118647
Entity TypeIndividualMale
Primary Taxonomy207RH0003X
Provider Legal NameDR. MATTHEW J KARPENKOCredential: DO
Location Address100 E CARROLL STSalisbury, MD 21801-5422
Mailing Address100 E Carroll StSalisbury, MD 21801-5422 · (410) 546-6400
Sole ProprietorNo
Medical School CMSLake Erie College Of Osteopathic Medicine, ErieGraduated 2002
Enumeration DateMay 24, 2007
Last NPPES UpdateAugust 14, 20264 updates tracked since enumeration
NPPES CertifiedAugust 14, 2026
NPI 1912118647 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses 3

Primary SpecialtyInternal Medicine · Hematology & OncologyAllopathic & Osteopathic Physicians
Taxonomy Code207RH0003X
Licenses Licensed in NC · 2010-01037 Licensed in VA · 0102209761 Licensed in NY · 254036
Definition
An internist doctor of osteopathy that specializes in the treatment of the combination of hematology and oncology disorders. A doctor of osteopathy that is board eligible/certified by the American Osteopathic Board of Internal Medicine WAS able to obtain a Certificate of Special Qualifications in the field of Hematology and Oncology. The Certificate is NO longer offered.
Also ListedInternal Medicine · HematologyTaxonomy 207RH0000X · License 0102209761 (VA)
Also ListedInternal Medicine · Medical OncologyTaxonomy 207RX0202X · License 0102209761 (VA)
100 E CARROLL ST, Salisbury, MD 21801

Secondary Practice Locations 5

Location 1134 Homer AveCortland, NY 13045-1206 · Phone (607) 756-3500
Location 258 Carroll StLebanon, VA 24266-4510 · Phone (276) 883-8070
Location 316000 Johnston Memorial Dr Ste AAbingdon, VA 24211-7664 · Phone (276) 258-1880 · Fax (276) 623-8155
Location 4245 Medical Park Dr Fl 3Marion, VA 24354-1100 · Phone (276) 378-3020
Location 55008 Brittonfield Pkwy Ste 700East Syracuse, NY 13057 · Phone (315) 472-7504 · Fax (315) 634-4677

Other Identifiers 1

Medicaid04615376NY

Accepted Insurance

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, and ordering and referring status from the CMS PECOS system.

Medicare Enrollment Status

Enrolled in Medicare and accepts Medicare assignment

Dr. Matthew J Karpenko Do is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID3476614835
PECOS Enrollment IDI20100723000531, I20100828000031, I20251209002951
Eligible to Order & Refer Part B Labs & Imaging Durable Medical Equipment Home Health Agency Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Areas of Expertise CMS Part B claims 3

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214
This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.
121 services85 patients
Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214
This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.
33 services29 patients
Established patient office or other outpatient visit with low level od decision making, if using time, 20 minutes or more 99213
This is a routine visit for patients who have already been seen by the healthcare provider. During this approximately 20-29 minute appointment, your health status will be evaluated and any necessary treatments or tests will be discussed. It's a chance to address any health concerns you may have.
27 services26 patients

Hospital Affiliations CMS Care Compare 5

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Cape Fear Valley Medical Center

Acute Care Hospitals · Fayetteville, NC
1/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number340028
Location1638 Owen Drive P O Box 2000Fayetteville, NC 28302 · Cumberland County
Emergency services Birthing friendly

Caromont Regional Medical Center

Acute Care Hospitals · Gastonia, NC
3/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number340032
Location2525 Court DrGastonia, NC 28052 · Gaston County
Emergency services Birthing friendly

Firsthealth Moore Regional Hospital

Acute Care Hospitals · Pinehurst, NC
4/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number340115
Location155 Memorial DrivePinehurst, NC 28374 · Moore County
Emergency services Birthing friendly

Musc Medical Center

Acute Care Hospitals · Charleston, SC
2/5 CMS rating
OwnershipGovernment - Hospital District or Authority
CMS Certification Number420004
Location169 Ashley AveCharleston, SC 29425 · Charleston County
Emergency services Birthing friendly

Sovah Health Danville

Acute Care Hospitals · Danville, VA
2/5 CMS rating
OwnershipProprietary
CMS Certification Number490075
Location142 South Main StreetDanville, VA 24541 · Danville City County
Emergency services Birthing friendly

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 21801 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient
$175.57 typical visit price
range $57.99 – $175.57
Typical copayment $43.89 (range $14.49 – $43.89)
Most-billed visit code 99205
Established Patient
$102.11 typical visit price
range $18.66 – $143.02
Typical copayment $25.52 (range $4.66 – $35.75)
Most-billed visit code 99214
Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Medicare Quality Performance CMS QPP · MIPS

Performance in the CMS Quality Payment Program: the MIPS final score across four weighted categories, and the individual quality measures reported to Medicare.

Reported Quality Measures

Medication Reconciliation Post-Discharge
The percentage of discharges from any inpatient facility (e.g. hospital, skilled nursing facility, or rehabilitation facility) for patients 18 years and older of age seen within 30 days following discharge in the office by the physician, prescribing…
Patients 65+: 95% · 62 patients
93%76 patients
Providers report different measures because they deliver different services; reporting more or less information is not a reflection of quality. Star ratings appear only where CMS assigned them.

Referred Medical Equipment & Supplies CMS DME claims

Durable medical equipment, devices and supplies this provider ordered from DME suppliers for patients, from Medicare fee-for-service claims.

Capecitabine, oral, 500 mg J8521
Treatment-Treatment - Miscellaneous · category RX029N
3 suppliers17 claims1,372 services$0.71 avg. paid by Medicare
Dollar amounts are the average Medicare paid the supplier per service. They are not the cost to the patient.

Other Providers at the Same Location NPPES 20

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

Student in an Organized Health Care Education/Training Program
100 E CARROLL ST
SALISBURY, MD 21801
Pediatrics (Neonatal-Perinatal Medicine)
100 E CARROLL ST
SALISBURY, MD 21801
Anesthesiology
100 E CARROLL ST
SALISBURY, MD 21801
Speech-Language Pathologist
100 E CARROLL ST
SALISBURY, MD 21801
Student in an Organized Health Care Education/Training Program
100 E CARROLL ST
SALISBURY, MD 21801
Nurse Practitioner
100 E CARROLL ST
SALISBURY, MD 21801
Internal Medicine
100 E CARROLL ST, INPATIENT SERVICES
SALISBURY, MD 21801
Emergency Medicine
100 E CARROLL ST
SALISBURY, MD 21801

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Matthew Karpenko's NPI number?

The NPI number for Matthew Karpenko is 1912118647. It was assigned to this individual provider in the NPPES registry on May 24, 2007.

Where is Matthew Karpenko located?

Matthew Karpenko practices at 100 E Carroll St, Salisbury, MD 21801. The listed phone number is (410) 546-6400.

What is Matthew Karpenko's specialty?

The primary specialty registered for this NPI is Internal Medicine, specializing in Hematology & Oncology, with taxonomy code 207RH0003X.

Is Matthew Karpenko enrolled in Medicare?

Yes. Matthew Karpenko is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

What insurance does Matthew Karpenko accept?

Health plans from Ambetter from Absolute Total Care, Ambetter of North Carolina, Ambetter of Tennessee, Blue Cross and Blue Shield of NC and BlueCross BlueShield of South Carolina and 3 other insurers list Matthew Karpenko as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Matthew Karpenko affiliated with any hospitals?

According to CMS data, Matthew Karpenko is affiliated with Cape Fear Valley Medical Center, Caromont Regional Medical Center, Firsthealth Moore Regional Hospital, Musc Medical Center and Sovah Health Danville.

When was this NPI record last updated?

The NPPES record for Matthew Karpenko was last updated on August 14, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 8 days ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.