MATTHEW J MANICO PA
Prescription History 1871649921
Physician Assistant - Medical in Roanoke, VA
What does Matthew Manico prescribe?
In 2024, Matthew Manico wrote 798 Medicare prescriptions for 19 medications. The most prescribed was Anastrozole, with 387 prescriptions for 187 patients.
Medicare Part D only. These are prescriptions filled by people with Medicare drug coverage in 2024, from the CMS data released in 2026, the most recent year available. CMS does not publish medications with fewer than 11 prescriptions, so this is not a full list of what Matthew Manico prescribes.
Medications 19 medications
Prescriptions filled under Medicare Part D in 2024. Select a medication to see what it is used for and how it compares with other Virginia prescribers.
What it is used for
Anastrozole is used to treat breast cancer in women after menopause.
Compared with Virginia prescribers
Matthew Manico wrote 387 prescriptions for Anastrozole, about 6 times as often as the typical Virginia prescriber of it (65). Medicare paid $16.33 per fill, versus $18.01 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause.
Compared with Virginia prescribers
Matthew Manico wrote 58 prescriptions for Letrozole, about as often as the typical Virginia prescriber of it (59). Medicare paid $26.83 per fill, versus $24.05 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Gabapentin is used with other medications to prevent and control seizures.
Compared with Virginia prescribers
Matthew Manico wrote 55 prescriptions for Gabapentin, about 62% as often as the typical Virginia prescriber of it (89). Medicare paid $13.28 per fill, versus $13.47 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used by people with sickle cell anemia to reduce the number of painful crises caused by the disease and to reduce the need for blood transfusions.
Compared with Virginia prescribers
Matthew Manico wrote 45 prescriptions for Hydroxyurea, about 1.3 times as often as the typical Virginia prescriber of it (33). Medicare paid $16.95 per fill, versus $21.41 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy.
Compared with Virginia prescribers
Matthew Manico wrote 28 prescriptions for Ondansetron Hcl, about as often as the typical Virginia prescriber of it (31). Medicare paid $42.05 per fill, versus $23.07 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication contains 2 amide-type local anesthetics, lidocaine and prilocaine.
Compared with Virginia prescribers
Matthew Manico wrote 23 prescriptions for Lidocaine-Prilocaine, about as often as the typical Virginia prescriber of it (23). Medicare paid $14.97 per fill, versus $16.07 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment).
Compared with Virginia prescribers
Matthew Manico wrote 22 prescriptions for Prochlorperazine Maleate, about 81% as often as the typical Virginia prescriber of it (27). Medicare paid $9.68 per fill, versus $15.27 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery.
Compared with Virginia prescribers
Matthew Manico wrote 21 prescriptions for Eliquis, about 25% as often as the typical Virginia prescriber of it (85). Medicare paid $574.51 per fill, versus $886.94 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Prednisone is used to treat conditions such as arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders.
Compared with Virginia prescribers
Matthew Manico wrote 21 prescriptions for Prednisone, about half as often as the typical Virginia prescriber of it (49). Medicare paid $2.80 per fill, versus $4.45 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Tamoxifen is used to treat breast cancer.
Compared with Virginia prescribers
Matthew Manico wrote 19 prescriptions for Tamoxifen Citrate, about 63% as often as the typical Virginia prescriber of it (30). Medicare paid $37.41 per fill, versus $25.05 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers).
Compared with Virginia prescribers
Matthew Manico wrote 18 prescriptions for Omeprazole, about 20% as often as the typical Virginia prescriber of it (91). Medicare paid $6.10 per fill, versus $11.75 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Levothyroxine is used to treat an underactive thyroid (hypothyroidism).
Compared with Virginia prescribers
Matthew Manico wrote 15 prescriptions for Levothyroxine Sodium, about 11% as often as the typical Virginia prescriber of it (133). Medicare paid $15.18 per fill, versus $10.42 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is a mineral supplement used to treat or prevent low amounts of potassium in the blood.
Compared with Virginia prescribers
Matthew Manico wrote 15 prescriptions for Potassium Chloride, about 27% as often as the typical Virginia prescriber of it (56). Medicare paid $10.59 per fill, versus $20.16 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy.
Compared with Virginia prescribers
Matthew Manico wrote 14 prescriptions for Ondansetron Odt, about half as often as the typical Virginia prescriber of it (26). Medicare paid $8.08 per fill, versus $14.86 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Acyclovir is used to treat infections caused by certain types of viruses.
Compared with Virginia prescribers
Matthew Manico wrote 12 prescriptions for Acyclovir, about half as often as the typical Virginia prescriber of it (25). Medicare paid $9.89 per fill, versus $18.06 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
Alendronate is used to prevent and treat certain types of bone loss (osteoporosis) in adults.
Compared with Virginia prescribers
Matthew Manico wrote 12 prescriptions for Alendronate Sodium, about 29% as often as the typical Virginia prescriber of it (41). Medicare paid $7.97 per fill, versus $7.88 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat certain mental/mood disorders (such as depression, anxiety).
Compared with Virginia prescribers
Matthew Manico wrote 11 prescriptions for Duloxetine Hcl, about 22% as often as the typical Virginia prescriber of it (51). Medicare paid $21.34 per fill, versus $23.61 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
See also Warning section.
Compared with Virginia prescribers
Matthew Manico wrote 11 prescriptions for Lidocaine Hcl Viscous, about half as often as the typical Virginia prescriber of it (19). Medicare paid $18.84 per fill, versus $14.45 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
What it is used for
This medication is used to treat certain mental/mood disorders (such as depression, anxiety, panic attacks, and social anxiety disorder).
Compared with Virginia prescribers
Matthew Manico wrote 11 prescriptions for Venlafaxine Hcl Er, about 35% as often as the typical Virginia prescriber of it (32). Medicare paid $7.73 per fill, versus $22.29 statewide.
Volume reflects how many Medicare patients a practice sees as well as prescribing habits. It is not a measure of quality.
Questions about Matthew Manico’s prescriptions
What does Matthew Manico prescribe most?
In 2024 Medicare Part D data, Matthew Manico's most prescribed medications were Anastrozole (387), Letrozole (58) and Gabapentin (55).
How does Matthew Manico's prescribing compare with other Virginia prescribers?
Of the 19 medications with a state comparison, Matthew Manico prescribes 2 more often than the typical Virginia prescriber, 4 about as often and 13 less often. Volume reflects practice size as well as prescribing habits.
Does this list show every medication Matthew Manico prescribes?
No. It covers prescriptions filled by people with Medicare Part D drug coverage in 2024, and CMS leaves out any medication with fewer than 11 prescriptions.
About this data
This page shows one provider’s slice of public Medicare files. NPI Profile does not receive prescriptions or patient records.
| Source | What it provides here | Data year |
|---|---|---|
| CMS Medicare Part D Prescribers by Provider and Drug | Each medication, prescriptions, patients, 30-day fills, days of medication and cost. State comparisons average the Virginia prescribers of the same medication and form, where at least five wrote it. | 2024 (released 2026, the most recent available) |
| CMS Medicare Part D Drug Spending Dashboard | What each medication is used for. | 2024 |
- Only prescriptions filled by people with Medicare Part D drug coverage are counted. Private insurance, Medicaid and cash purchases are not.
- CMS leaves out medications with fewer than 11 prescriptions and hides patient counts under 11.
- Cost per fill is what the plan and the patient paid the pharmacy together, not what you pay at the counter.
- Medication descriptions are summaries from CMS. They are not medical advice; ask a health care professional about any medication.
