JOHN H HOLDEN M.D.
Prescription History 1851611321
Internal Medicine - Gastroenterology in Indianapolis, IN

Active since June 08, 2010PECOS EnrolledAccepts Medicare Assignment
1701 N SENATE BLVD, INDIANAPOLIS, IN 46202(888) 484-3258 Get Directions

NPPES record last updated: March 12, 2025. Verified against the NPPES registry weekly; last sync: October 18, 2026.

Record update history: Mar 12, 2025, Jan 13, 2021, Oct 27, 2017 (3 updates tracked since 2017).

Medicare Part D Prescription History

Explore the verified Medicare Part D prescription history, volume metrics, and calculated drug costs for JOHN H HOLDEN M.D., an active Gastroenterology specialist practicing in Indianapolis, IN. Our medical registry currently tracks 29 unique pharmaceutical formulations prescribed by this provider, representing an estimated volume of 1,390 documented patient claims. Among these therapy options, the most frequently utilized medication is Tacrolimus, which accounts for 259 claims alone. Use the table below to sort by claims, cost, or utilization compared with the state average; select any medication for its full profile.

29
Medications
1,390
Total Claims
2,732
30-Day Fills
Tacrolimus
Most Prescribed · 259 claims
View details
29 medications · 2024 Medicare Part D
Medicare Part D medications prescribed by JOHN H HOLDEN M.D. in 2024, with prescription volumes, average cost per fill, and IN state comparisons
Medication Prescriptions (2024)Rx (2024) Avg Cost per FillCost / Fill Vs. Other IN PrescribersVs. IN Avg

About Tacrolimus: This form of tacrolimus is used on the skin to treat a skin condition called eczema (atopic dermatitis) in patients who have not responded well to (or should not use) other eczema medications. Show more ▾

Eczema is an allergic-type condition that causes red, irritated, and itchy skin. This drug works by weakening the skin's defense (immune) system, thereby decreasing the allergic reaction and relieving the eczema. Tacrolimus belongs to a class of drugs known as topical calcineurin inhibitors (TCIs). For children 2 to 15 years of age, the lower strength product should be used. This medication is not recommended if you have a history of a certain rare genetic disorder (Netherton's syndrome). Also, this medication should not be used by anyone who has a weakened immune system (for example, following an organ transplant). A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.

In 2024, this provider wrote 259 Medicare prescriptions for Tacrolimus, about 7.3 times the volume of the typical Indiana prescriber of this medication (35.3). Medicare paid an average of $127.18 per fill, versus $119.22 statewide.

How often this provider prescribes it

This provider
259
IN average
35.3

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$127.18
IN average
$119.22

Gross Part D cost per fill; not the patient's out-of-pocket price.

605
30-Day Fills
standardized to 30-day supplies
17,989
Days of Medication
total across all patients in 2024

About Furosemide: Furosemide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. Show more ▾

This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Furosemide is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt. A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.

In 2024, this provider wrote 112 Medicare prescriptions for Furosemide, about the same volume as the typical Indiana prescriber of this medication (99). Medicare paid an average of $2.80 per fill, versus $4.55 statewide.

How often this provider prescribes it

This provider
112
IN average
99.0

This provider's prescribing volume for this medication is in line with the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$2.80
IN average
$4.55

This provider's average cost per fill is below the IN average for this medication.

202
30-Day Fills
standardized to 30-day supplies
6,060
Days of Medication
total across all patients in 2024

About Spironolactone: Spironolactone is used to treat high blood pressure and heart failure. Show more ▾

Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat conditions in which the body is making too much of a natural substance (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic). A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)

In 2024, this provider wrote 90 Medicare prescriptions for Spironolactone, about 1.6 times the volume of the typical Indiana prescriber of this medication (54.6). Medicare paid an average of $15.24 per fill, versus $8.00 statewide.

How often this provider prescribes it

This provider
90
IN average
54.6

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$15.24
IN average
$8.00

Gross Part D cost per fill; not the patient's out-of-pocket price.

162
30-Day Fills
standardized to 30-day supplies
4,833
Days of Medication
total across all patients in 2024

About Sirolimus: Sirolimus is used with other medications to prevent rejection of a kidney transplant. Show more ▾

This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own. Sirolimus may also be used to treat a certain lung disease (lymphangioleiomyomatosis-LAM). A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.

In 2024, this provider wrote 88 Medicare prescriptions for Sirolimus, about 2.5 times the volume of the typical Indiana prescriber of this medication (34.8). Medicare paid an average of $647.49 per fill, versus $373.49 statewide.

How often this provider prescribes it

This provider
88
IN average
34.8

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$647.49
IN average
$373.49

Gross Part D cost per fill; not the patient's out-of-pocket price.

174
30-Day Fills
standardized to 30-day supplies
5,210
Days of Medication
total across all patients in 2024

About Ursodiol: Ursodiol is used to dissolve certain types of gallstones, to prevent gallstones from forming in obese patients who are losing weight rapidly, and to treat a certain type of liver disease (primary biliary cholangitis). Show more ▾

Ursodiol is a bile acid. An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.

In 2024, this provider wrote 87 Medicare prescriptions for Ursodiol, about 3.4 times the volume of the typical Indiana prescriber of this medication (26). Medicare paid an average of $249.01 per fill, versus $167.66 statewide.

How often this provider prescribes it

This provider
87
IN average
26.0

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$249.01
IN average
$167.66

Gross Part D cost per fill; not the patient's out-of-pocket price.

204
30-Day Fills
standardized to 30-day supplies
6,120
Days of Medication
total across all patients in 2024

About Mycophenolate Mofetil: Mycophenolate is used in combination with other medications to keep your body from attacking and rejecting your transplanted organ (such as kidney, liver, heart). Show more ▾

It belongs to a class of medications called immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own. Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION.

In 2024, this provider wrote 78 Medicare prescriptions for Mycophenolate Mofetil, about 2.8 times the volume of the typical Indiana prescriber of this medication (27.8). Medicare paid an average of $180.88 per fill, versus $119.44 statewide.

How often this provider prescribes it

This provider
78
IN average
27.8

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$180.88
IN average
$119.44

Gross Part D cost per fill; not the patient's out-of-pocket price.

195.3
30-Day Fills
standardized to 30-day supplies
5,860
Days of Medication
total across all patients in 2024

About Eliquis: Apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery. Show more ▾

With atrial fibrillation, part of the heart does not beat the way it should. This can lead to blood clots forming, which can travel to other parts of your body (such as the lungs or legs) or increase your risk for stroke. In the United States, apixaban is also approved to treat certain types of blood clots (deep vein thrombosis-DVT, pulmonary embolus-PE) and to prevent them from forming again. Apixaban is an anticoagulant that works by blocking certain clotting proteins in your blood. An antithrombotic agent.

In 2024, this provider wrote 74 Medicare prescriptions for Eliquis, about 72% of the volume of the typical Indiana prescriber of this medication (102.9). Medicare paid an average of $686.01 per fill, versus $840.97 statewide.

How often this provider prescribes it

This provider
74
IN average
102.9

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$686.01
IN average
$840.97

This provider's average cost per fill is below the IN average for this medication.

90
30-Day Fills
standardized to 30-day supplies
2,640
Days of Medication
total across all patients in 2024

About Carvedilol: Carvedilol is used to treat high blood pressure and heart failure. Show more ▾

It is also used after a heart attack to improve the chance of survival if your heart is not pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers your heart rate, blood pressure, and strain on your heart. Carvedilol belongs to a class of drugs known as alpha and beta blockers. A carbazole and propanol derivative that acts as a non-cardioselective beta blocker and vasodilator. It has blocking activity for ALPHA 1 ADRENERGIC RECEPTORS and, at higher doses, may function as a blocker of CALCIUM CHANNELS; it also has antioxidant properties. Carvedilol is used in the treatment of HYPERTENSION; ANGINA PECTORIS; and HEART FAILURE. It can also reduce the risk of death following MYOCARDIAL INFARCTION.

In 2024, this provider wrote 71 Medicare prescriptions for Carvedilol, about 87% of the volume of the typical Indiana prescriber of this medication (81.3). Medicare paid an average of $4.09 per fill, versus $7.58 statewide.

How often this provider prescribes it

This provider
71
IN average
81.3

This provider's prescribing volume for this medication is in line with the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$4.09
IN average
$7.58

This provider's average cost per fill is below the IN average for this medication.

145
30-Day Fills
standardized to 30-day supplies
4,322
Days of Medication
total across all patients in 2024

About Mycophenolic Acid: Mycophenolate is used in combination with other medications to keep your body from attacking and rejecting your transplanted kidney. Show more ▾

It belongs to a class of medications called immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new kidney as if it were your own. Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION.

In 2024, this provider wrote 64 Medicare prescriptions for Mycophenolic Acid, about 2.2 times the volume of the typical Indiana prescriber of this medication (29). Medicare paid an average of $387.91 per fill, versus $333.70 statewide.

How often this provider prescribes it

This provider
64
IN average
29.0

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$387.91
IN average
$333.70

Gross Part D cost per fill; not the patient's out-of-pocket price.

143
30-Day Fills
standardized to 30-day supplies
4,200
Days of Medication
total across all patients in 2024

About Pantoprazole Sodium: Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). Show more ▾

It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.

In 2024, this provider wrote 47 Medicare prescriptions for Pantoprazole Sodium, about half the volume of the typical Indiana prescriber of this medication (95). Medicare paid an average of $15.77 per fill, versus $12.28 statewide.

How often this provider prescribes it

This provider
47
IN average
95.0

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$15.77
IN average
$12.28

Gross Part D cost per fill; not the patient's out-of-pocket price.

113
30-Day Fills
standardized to 30-day supplies
3,390
Days of Medication
total across all patients in 2024

About Cyclosporine Modified: Cyclosporine is used to prevent organ rejection in people who have received a liver, kidney, or heart transplant. Show more ▾

It is usually taken along with other medications to allow your new organ to function normally. Cyclosporine is also used to treat severe cases of rheumatoid arthritis and plaque psoriasis. In these conditions, the body's defense system (immune system) attacks healthy tissues. Cyclosporine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new organ as if it were your own (in the case of an organ transplant) and to prevent further damage to your joints (in the case of rheumatoid arthritis) or skin (in the case of psoriasis).

In 2024, this provider wrote 47 Medicare prescriptions for Cyclosporine Modified, about 2.4 times the volume of the typical Indiana prescriber of this medication (19.9). Medicare paid an average of $279.97 per fill, versus $196.58 statewide.

How often this provider prescribes it

This provider
47
IN average
19.9

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$279.97
IN average
$196.58

Gross Part D cost per fill; not the patient's out-of-pocket price.

137
30-Day Fills
standardized to 30-day supplies
4,095
Days of Medication
total across all patients in 2024

About Xifaxan: This medication is used to treat diarrhea caused by the common bacteria known as E. Show more ▾

coli ("traveler's diarrhea"). Rifaximin should not be used if you have a fever or bloody diarrhea. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. Rifaximin is also used to treat irritable bowel syndrome with diarrhea. It is also used to prevent a brain problem caused by liver disease (hepatic encephalopathy). A synthetic rifamycin derivative and anti-bacterial agent that is used for the treatment of GASTROENTERITIS caused by ESCHERICHIA COLI INFECTIONS. It may also be used in the treatment of HEPATIC ENCEPHALOPATHY.

In 2024, this provider wrote 37 Medicare prescriptions for Xifaxan, about 1.3 times the volume of the typical Indiana prescriber of this medication (28.7). Medicare paid an average of $3,385.65 per fill, versus $2,665.43 statewide.

How often this provider prescribes it

This provider
37
IN average
28.7

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$3,385.65
IN average
$2,665.43

Gross Part D cost per fill; not the patient's out-of-pocket price.

37
30-Day Fills
standardized to 30-day supplies
1,106
Days of Medication
total across all patients in 2024

About Lamivudine Hbv: Lamivudine-HBV is used to treat hepatitis B infection. Show more ▾

It is not a cure for hepatitis B and does not prevent the passing of hepatitis B to others. This medication is a nucleoside reverse transcriptase inhibitor (NRTI) that works by slowing the growth of the virus, thereby decreasing liver damage caused by the virus. A reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.

In 2024, this provider wrote 32 Medicare prescriptions for Lamivudine Hbv, about 1.8 times the volume of the typical Indiana prescriber of this medication (18.1). Medicare paid an average of $89.98 per fill, versus $162.50 statewide.

How often this provider prescribes it

This provider
32
IN average
18.1

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$89.98
IN average
$162.50

This provider's average cost per fill is below the IN average for this medication.

44
30-Day Fills
standardized to 30-day supplies
1,320
Days of Medication
total across all patients in 2024

About Azathioprine: Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. Show more ▾

It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body's defense system (immune system) attacks healthy joints. Azathioprine belongs to a class of drugs known as immunosuppressants. It works by weakening the immune system to help your body accept the new kidney as if it were your own (in the case of an organ transplant) or to prevent further damage to your joints (in the case of rheumatoid arthritis). Talk to your doctor about the risks and benefits of azathioprine, especially when used by children and young adults. An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)

In 2024, this provider wrote 32 Medicare prescriptions for Azathioprine, about 1.3 times the volume of the typical Indiana prescriber of this medication (24.7). Medicare paid an average of $28.31 per fill, versus $43.93 statewide.

How often this provider prescribes it

This provider
32
IN average
24.7

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$28.31
IN average
$43.93

This provider's average cost per fill is below the IN average for this medication.

72
30-Day Fills
standardized to 30-day supplies
2,160
Days of Medication
total across all patients in 2024

About Lactulose: This medication is a laxative used to treat constipation. Show more ▾

It may help to increase the number of bowel movements per day and the number of days you have a bowel movement. Lactulose is a colonic acidifier that works by increasing stool water content and softening the stool. It is a man-made sugar solution. A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887)

In 2024, this provider wrote 31 Medicare prescriptions for Lactulose, about the same volume as the typical Indiana prescriber of this medication (28.9). Medicare paid an average of $26.42 per fill, versus $26.36 statewide.

How often this provider prescribes it

This provider
31
IN average
28.9

This provider's prescribing volume for this medication is in line with the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$26.42
IN average
$26.36

Gross Part D cost per fill; not the patient's out-of-pocket price.

40.2
30-Day Fills
standardized to 30-day supplies
1,157
Days of Medication
total across all patients in 2024

About Entecavir: See also Warning section. Show more ▾

Entecavir is used to treat long-term hepatitis B infection. Hepatitis B is an infection of the liver caused by the hepatitis B virus. Long-term infection can cause liver damage, rarely liver cancer, and liver failure. Entecavir helps to decrease the amount of hepatitis B virus in your body. It is unknown if this medication lowers your chance of getting liver cancer or liver damage. Entecavir is an antiviral that belongs to a class of drugs known as hepatitis B virus nucleoside reverse transcriptase inhibitors. Entecavir is not a cure for hepatitis B. It does not prevent the spread of the virus to others through sexual contact or blood/body fluid contamination (such as sharing used needles).

In 2024, this provider wrote 27 Medicare prescriptions for Entecavir, about 1.4 times the volume of the typical Indiana prescriber of this medication (18.9). Medicare paid an average of $154.74 per fill, versus $181.91 statewide.

How often this provider prescribes it

This provider
27
IN average
18.9

This provider prescribes this medication more often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$154.74
IN average
$181.91

This provider's average cost per fill is below the IN average for this medication.

53
30-Day Fills
standardized to 30-day supplies
1,590
Days of Medication
total across all patients in 2024

About Prednisone: Prednisone is used to treat conditions such as arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders. Show more ▾

Prednisone belongs to a class of drugs known as corticosteroids. It decreases your immune system's response to various diseases to reduce symptoms such as swelling and allergic-type reactions. A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.

In 2024, this provider wrote 23 Medicare prescriptions for Prednisone, about half the volume of the typical Indiana prescriber of this medication (48.5). Medicare paid an average of $5.44 per fill, versus $3.47 statewide.

How often this provider prescribes it

This provider
23
IN average
48.5

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$5.44
IN average
$3.47

Gross Part D cost per fill; not the patient's out-of-pocket price.

27
30-Day Fills
standardized to 30-day supplies
755
Days of Medication
total across all patients in 2024

About Gavilyte-G: PEG (polyethylene glycol) with electrolyte is used to clean out the intestines before certain bowel exam procedures such as colonoscopy or barium enema X-rays. Show more ▾

It is a laxative that works by drawing large amounts of water into the colon. This effect results in watery bowel movements. Clearing stool from the intestines helps your doctor to better examine the intestines during your procedure.

In 2024, this provider wrote 21 Medicare prescriptions for Gavilyte-G, about a third of the volume of the typical Indiana prescriber of this medication (67.4). Medicare paid an average of $12.52 per fill, versus $13.37 statewide.

How often this provider prescribes it

This provider
21
IN average
67.4

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$12.52
IN average
$13.37

This provider's average cost per fill is below the IN average for this medication.

21
30-Day Fills
standardized to 30-day supplies
36
Days of Medication
total across all patients in 2024

About Tenofovir Disoproxil Fumarate: Tenofovir is used with other HIV medications to help control HIV infection. Show more ▾

It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Tenofovir belongs to a class of drugs known as nucleotide reverse transcriptase inhibitors (NRTIs). Tenofovir is not a cure for HIV infection. To decrease your risk of spreading HIV disease to others, continue to take all HIV medications exactly as prescribed by your doctor. Use an effective barrier method (latex or polyurethane condoms/dental dams) during sexual activity as directed by your doctor. Do not share personal items (such as needles/syringes, toothbrushes, and razors) that may have contacted blood or other body fluids. Consult your doctor or pharmacist for more details. Tenofovir is also used to treat a certain type of liver infection called chronic hepatitis B infection. It helps to decrease the amount of hepatitis B virus in your body by interfering with virus growth. An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.

In 2024, this provider wrote 21 Medicare prescriptions for Tenofovir Disoproxil Fumarate, about the same volume as the typical Indiana prescriber of this medication (19.9). Medicare paid an average of $351.13 per fill, versus $173.20 statewide.

How often this provider prescribes it

This provider
21
IN average
19.9

This provider's prescribing volume for this medication is in line with the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$351.13
IN average
$173.20

Gross Part D cost per fill; not the patient's out-of-pocket price.

43
30-Day Fills
standardized to 30-day supplies
1,265
Days of Medication
total across all patients in 2024

About Rifampin: This medication is used to prevent and treat tuberculosis and other bacterial infections. Show more ▾

Rifampin belongs to a class of drugs known as rifamycin antibiotics. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)

In 2024, this provider wrote 21 Medicare prescriptions for Rifampin, about 83% of the volume of the typical Indiana prescriber of this medication (25.2). Medicare paid an average of $21.87 per fill, versus $57.13 statewide.

How often this provider prescribes it

This provider
21
IN average
25.2

This provider's prescribing volume for this medication is in line with the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$21.87
IN average
$57.13

This provider's average cost per fill is below the IN average for this medication.

21
30-Day Fills
standardized to 30-day supplies
630
Days of Medication
total across all patients in 2024

About Amlodipine Besylate: Amlodipine is used with or without other medications to treat high blood pressure. Show more ▾

Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Amlodipine belongs to a class of drugs known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily. Amlodipine is also used to prevent certain types of chest pain (angina). It may help to increase your ability to exercise and decrease the frequency of angina attacks. It should not be used to treat attacks of chest pain when they occur. Use other medications (such as sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor. A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.

In 2024, this provider wrote 19 Medicare prescriptions for Amlodipine Besylate, about 12% of the volume of the typical Indiana prescriber of this medication (161.5). Medicare paid an average of $2.68 per fill, versus $5.38 statewide.

How often this provider prescribes it

This provider
19
IN average
161.5

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$2.68
IN average
$5.38

This provider's average cost per fill is below the IN average for this medication.

41
30-Day Fills
standardized to 30-day supplies
1,230
Days of Medication
total across all patients in 2024

About Hydroxyzine Hcl: Hydroxyzine is used to treat itching caused by allergies. Show more ▾

It is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Hydroxyzine may also be used short-term to treat anxiety or to help you feel sleepy/relaxed before and after surgery. A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.

In 2024, this provider wrote 17 Medicare prescriptions for Hydroxyzine Hcl, about half the volume of the typical Indiana prescriber of this medication (34.1). Medicare paid an average of $18.22 per fill, versus $16.96 statewide.

How often this provider prescribes it

This provider
17
IN average
34.1

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$18.22
IN average
$16.96

Gross Part D cost per fill; not the patient's out-of-pocket price.

21
30-Day Fills
standardized to 30-day supplies
510
Days of Medication
total across all patients in 2024

About Constulose: This medication is a laxative used to treat constipation. Show more ▾

It may help to increase the number of bowel movements per day and the number of days you have a bowel movement. Lactulose is a colonic acidifier that works by increasing stool water content and softening the stool. It is a man-made sugar solution. A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887)

In 2024, this provider wrote 16 Medicare prescriptions for Constulose, about the same volume as the typical Indiana prescriber of this medication (14.1). Medicare paid an average of $32.10 per fill, versus $24.77 statewide.

How often this provider prescribes it

This provider
16
IN average
14.1

This provider's prescribing volume for this medication is in line with the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$32.10
IN average
$24.77

Gross Part D cost per fill; not the patient's out-of-pocket price.

20
30-Day Fills
standardized to 30-day supplies
598
Days of Medication
total across all patients in 2024

About Omeprazole: Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). Show more ▾

It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). If you are self-treating with this medication, over-the-counter omeprazole products are used to treat frequent heartburn (occurring 2 or more days a week). Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away. For over-the-counter products, carefully read the package instructions to make sure the product is right for you. Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar brand names may contain different ingredients meant for different purposes. Taking the wrong product could harm you. A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

In 2024, this provider wrote 15 Medicare prescriptions for Omeprazole, about 14% of the volume of the typical Indiana prescriber of this medication (111). Medicare paid an average of $3.74 per fill, versus $12.17 statewide.

How often this provider prescribes it

This provider
15
IN average
111.0

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$3.74
IN average
$12.17

This provider's average cost per fill is below the IN average for this medication.

32
30-Day Fills
standardized to 30-day supplies
944
Days of Medication
total across all patients in 2024

About Everolimus: Everolimus is used to treat various types of cancer (such as kidney, breast, pancreas, lung, stomach/intestinal cancers). Show more ▾

Everolimus is also used in people with a certain genetic disorder (tuberous sclerosis complex) to treat certain types of benign tumors in the brain or kidney. It works by slowing or stopping the growth of cancer or tumor cells. A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.

In 2024, this provider wrote 15 Medicare prescriptions for Everolimus, about 78% of the volume of the typical Indiana prescriber of this medication (19.2). Medicare paid an average of $1,781.74 per fill, versus $3,442.28 statewide.

How often this provider prescribes it

This provider
15
IN average
19.2

This provider's prescribing volume for this medication is in line with the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$1,781.74
IN average
$3,442.28

This provider's average cost per fill is below the IN average for this medication.

23
30-Day Fills
standardized to 30-day supplies
690
Days of Medication
total across all patients in 2024

About Ciprofloxacin Hcl: This medication is used to treat a variety of bacterial infections. Show more ▾

Ciprofloxacin belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for virus infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. A broad-spectrum antimicrobial carboxyfluoroquinoline.

In 2024, this provider wrote 12 Medicare prescriptions for Ciprofloxacin Hcl, about a third of the volume of the typical Indiana prescriber of this medication (28.9). Medicare paid an average of $5.17 per fill, versus $6.74 statewide.

How often this provider prescribes it

This provider
12
IN average
28.9

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$5.17
IN average
$6.74

This provider's average cost per fill is below the IN average for this medication.

20.2
30-Day Fills
standardized to 30-day supplies
529
Days of Medication
total across all patients in 2024

About Vemlidy: Tenofovir alafenamide is used to treat chronic hepatitis B infection, a viral infection of the liver. Show more ▾

It works by stopping or slowing the growth of the virus. Chronic hepatitis infection can lead to serious liver damage (cirrhosis) and liver cancer. It is not known if tenofovir alafenamide can cure hepatitis B or can prevent you from passing the virus to others. Practice "safer sex" (such as the use of latex condoms) to lower the risk of passing the virus to others. Component of Biktarvy.

In 2024, this provider wrote 12 Medicare prescriptions for Vemlidy, about 70% of the volume of the typical Indiana prescriber of this medication (17.1). Medicare paid an average of $1,401.98 per fill, versus $1,552.76 statewide.

How often this provider prescribes it

This provider
12
IN average
17.1

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$1,401.98
IN average
$1,552.76

This provider's average cost per fill is below the IN average for this medication.

12
30-Day Fills
standardized to 30-day supplies
360
Days of Medication
total across all patients in 2024

About Potassium Chloride: This medication is a mineral supplement used to treat or prevent low amounts of potassium in the blood. Show more ▾

A normal level of potassium in the blood is important. Potassium helps your cells, kidneys, heart, muscles, and nerves work properly. Most people get enough potassium by eating a well-balanced diet. Some conditions that can lower your body's potassium level include severe prolonged diarrhea and vomiting, hormone problems such as hyperaldosteronism, or treatment with "water pills"/diuretics. A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.

In 2024, this provider wrote 11 Medicare prescriptions for Potassium Chloride, about 14% of the volume of the typical Indiana prescriber of this medication (77.1). Medicare paid an average of $5.13 per fill, versus $19.91 statewide.

How often this provider prescribes it

This provider
11
IN average
77.1

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$5.13
IN average
$19.91

This provider's average cost per fill is below the IN average for this medication.

13
30-Day Fills
standardized to 30-day supplies
390
Days of Medication
total across all patients in 2024

About Mirtazapine: This medication is used to treat depression. Show more ▾

Mirtazapine works by helping to restore the balance of certain natural substances in the brain. A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

In 2024, this provider wrote 11 Medicare prescriptions for Mirtazapine, about a quarter of the volume of the typical Indiana prescriber of this medication (48.2). Medicare paid an average of $19.99 per fill, versus $19.71 statewide.

How often this provider prescribes it

This provider
11
IN average
48.2

This provider prescribes this medication less often than the average IN prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$19.99
IN average
$19.71

Gross Part D cost per fill; not the patient's out-of-pocket price.

21
30-Day Fills
standardized to 30-day supplies
630
Days of Medication
total across all patients in 2024
No medications match the current filters.
= the 5 medications this provider prescribes most.▲ More than typical≈ Typical▼ Less than typical= prescription volume vs the average IN prescriber of the same medication; volume reflects practice size as well as clinical preference.Green cost= below the IN average cost per fill.

About this data. The prescription history for JOHN H HOLDEN M.D. is compiled from the Centers for Medicare & Medicaid Services (CMS) Medicare Part D Prescriber Public Use File for calendar year 2024, the most recent federal release. Figures cover prescriptions filled for Medicare Part D beneficiaries only; prescriptions under private insurance, Medicaid, or self-pay plans are not included. Because prescribing decisions are generally consistent across coverage types, this record offers a useful view of the overall Gastroenterology prescribing approach at this Indianapolis, IN practice.

Reading the costs. Drug costs are gross amounts paid to pharmacies under Part D, including both plan and beneficiary payments. They are not the price a patient pays at the pharmacy counter. Medications with fewer than 11 claims are excluded from the federal source data, and state comparisons use the average among IN prescribers of the same medication and form, shown only when at least five prescribers contribute. Always confirm current medications and costs directly with the provider and your plan.

About the medication summaries. Drug use descriptions come from the CMS Medicare Part D Drug Spending Dashboard (2024), and substance definitions from Medical Subject Headings (MeSH) 2026, U.S. National Library of Medicine. They are summaries that do not contain all possible information about a medication and are not individual medical advice. Ask a health care professional about any medication and your specific health needs.