Recently Updated NPI Information — some details in this NPI profile have been updated in the NPI registry within the last 30 days.

SAMANTHA KARLE MD
NPI 1831891639
Internal Medicine in Boston, MA

Active since March 17, 2023PECOS Enrolled

NPPES record last updated: July 8, 2026. Verified against the NPPES registry weekly; last sync: July 19, 2026.

Record update history: Jul 8, 2026, Mar 17, 2023 (2 updates tracked since 2023).

About Samantha Karle Md NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

SAMANTHA KARLE MD (NPI 1831891639) is an individual internal medicine provider in Boston, Massachusetts, licensed in Massachusetts (1027044) and active in the NPI registry since March 2023. She is enrolled in Medicare PECOS.

NPPES Registry Identity

NPI1831891639
Entity TypeIndividualFemale
Primary Taxonomy207R00000X
Provider Legal NameSAMANTHA KARLECredential: MD
Location Address55 FRUIT STBoston, MA 02114-2621
Mailing Address55 Fruit StBoston, MA 02114-2696 · (617) 726-2000
Sole ProprietorNo
Enumeration DateMarch 17, 2023
Last NPPES UpdateJuly 8, 20262 updates tracked since enumeration
NPPES CertifiedJuly 8, 2026
NPI 1831891639 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

Primary SpecialtyInternal MedicineAllopathic & Osteopathic Physicians
Taxonomy Code207R00000X
License Licensed in MA · 1027044
Definition

A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults and the elderly. Internists are trained in the diagnosis and treatment of cancer, infections and diseases affecting the heart, blood, kidneys, joints and digestive, respiratory and vascular systems. They are also trained in the essentials of primary care internal medicine, which incorporates an understanding of disease prevention, wellness, substance abuse, mental health and effective treatment of common problems of the eyes, ears, skin, nervous system and reproductive organs.

55 FRUIT ST, Boston, MA 02114

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, and ordering and referring status from the CMS PECOS system.

Medicare Enrollment Status

Enrolled in Medicare (PECOS)

Samantha Karle Md is registered in the CMS Provider Enrollment, Chain and Ownership System (PECOS).

Eligible to Order & Refer Part B Labs & Imaging Durable Medical Equipment Home Health Agency Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 02114 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient
$144.11 typical visit price
range $63.72 – $189.86
Typical copayment $36.02 (range $15.93 – $47.46)
Most-billed visit code 99204
Established Patient
$111.18 typical visit price
range $21.07 – $155.29
Typical copayment $27.79 (range $5.26 – $38.82)
Most-billed visit code 99214
Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Other Providers at the Same Location NPPES 20

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

Internal Medicine (Gastroenterology)
55 FRUIT ST
BOSTON, MA 02114
Psychiatry & Neurology (Psychiatry)
55 FRUIT ST, WARREN 1220
BOSTON, MA 02114
Thoracic Surgery (Cardiothoracic Vascular Surgery)
55 FRUIT ST, MGH, BULFINCH 2
BOSTON, MA 02114
Psychologist
55 FRUIT ST, YAW 6A MASSACHUSSETTS GENERAL HOSPITAL
BOSTON, MA 02114
Anesthesiology (Critical Care Medicine)
55 FRUIT ST, ANESTHESIA ASSOCIATES GRB 406E
BOSTON, MA 02114
Internal Medicine (Rheumatology)
55 FRUIT ST, RHEUMATOLOGY ASSOCIATES YAW 2100
BOSTON, MA 02114
Neurological Surgery
55 FRUIT ST, MASSACHUSETTS GENERAL HOSPITAL, WAC 745K
BOSTON, MA 02114
Anesthesiology
55 FRUIT ST, WHITE 525
BOSTON, MA 02114

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Samantha Karle's NPI number?

The NPI number for Samantha Karle is 1831891639. It was assigned to this individual provider in the NPPES registry on March 17, 2023.

Where is Samantha Karle located?

Samantha Karle practices at 55 Fruit St, Boston, MA 02114. The listed phone number is (617) 726-2000.

What is Samantha Karle's specialty?

The primary specialty registered for this NPI is Internal Medicine with taxonomy code 207R00000X.

Is Samantha Karle enrolled in Medicare?

Yes. Samantha Karle is registered in the Medicare PECOS enrollment system.

When was this NPI record last updated?

The NPPES record for Samantha Karle was last updated on July 8, 2026. NPI Profile syncs with the weekly NPPES data releases published by CMS.