PRISMA HEALTH CANCER INST-SENECA
NPI 1821544925
General Acute Care Hospital in Seneca, SC

Active since August 29, 2016
131 LILA DOYLE DR, SENECA, SC 29672(864) 888-3717 Get Directions Write a Review

NPPES record last updated: February 5, 2021. Verified against the NPPES registry weekly; last sync: October 25, 2026.

Record update history: Feb 5, 2021, Apr 13, 2020, May 15, 2019 and 2 more (5 updates tracked since 2016).

About Prisma Health Cancer Inst-seneca NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

PRISMA HEALTH CANCER INST-SENECA (NPI 1821544925) is a healthcare organization registered as a general acute care hospital in Seneca, South Carolina and active in the NPI registry since August 2016. The organization lists Polly H. Miller, Vp Payor Strategies & Alignment, as its authorized official.

NPPES Registry Identity

NPI1821544925
Entity TypeOrganization
Primary Taxonomy282N00000X
Legal Business NamePRISMA HEALTH-UPSTATE
Location Address131 LILA DOYLE DRSeneca, SC 29672-9495
Mailing Address300 E Mcbee Ave Fl 4Greenville, SC 29601-2842 · (864) 455-7000
Organization SubpartNo
Authorized OfficialPolly H. MillerVp Payor Strategies & Alignment · (864) 522-2286
Enumeration DateAugust 29, 2016
Last NPPES UpdateFebruary 5, 20215 updates tracked since enumeration
NPPES CertifiedFebruary 5, 2021
✔ NPI 1821544925 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyGeneral Acute Care HospitalHospitals
Taxonomy Code282N00000X
License✔ Licensed in SC · HTL-0936
Definition
An acute general hospital is an institution whose primary function is to provide inpatient diagnostic and therapeutic services for a variety of medical conditions, both surgical and non-surgical, to a wide population group. The hospital treats patients in an acute phase of illness or injury, characterized by a single episode or a fairly short duration, from which the patient returns to his or her normal or previous level of activity.
131 LILA DOYLE DR, Seneca, SC 29672

Other Names 1

Doing Business AsPrisma Health Cancer Inst-seneca

Accepted Insurance

Medicare Participation & PECOS CMS

Medicare enrollment and the clinicians who bill Medicare through this organization, from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare (PECOS)

Prisma Health Cancer Inst-seneca is registered in the CMS Provider Enrollment, Chain and Ownership System (PECOS).

Clinicians Billing Medicare Through This Organization

412

Medicare enrollment records show 412 clinicians reassign Medicare billing to Prisma Health Cancer Inst-Seneca, which bills Medicare for the services they deliver. Of these, 7 practice within 10 miles. Listed here are the 20 practicing nearest to this location.

Clinicians by Medicare Specialty 13

Certified Registered Nurse Anesthetist (CRNA)267
Emergency Medicine99
Nurse Practitioner20
Anesthesiology Assistant9
Pediatric Medicine5
Family Practice3
Clinical Psychologist2
Sports Medicine2
5 other specialties5

Nearest to this location (20)

See all 412
Certified Registered Nurse Anesthetist (CRNA)
NPI 1588634786
298 MEMORIAL DR
Seneca, SC 29672
(864) 885-7156
✔ PECOS✔ Accepts Medicare0.1 mi
Emergency Medicine
NPI 1255309746
298 MEMORIAL DR
Seneca, SC 29672
(864) 882-3351
✔ PECOS0.1 mi
Nurse Practitioner
NPI 1861584419
298 MEMORIAL DR
Seneca, SC 29672
(864) 885-7156
✔ PECOS✔ Accepts Medicare0.1 mi
Emergency Medicine
NPI 1194793661
298 MEMORIAL DR
Seneca, SC 29672
(864) 882-3351
✔ PECOS✔ Accepts Medicare0.1 mi
Certified Registered Nurse Anesthetist (CRNA)
NPI 1962608687
298 MEMORIAL DR
Seneca, SC 29672
(864) 482-3100
✔ Accepts Medicare0.1 mi
Emergency Medicine
NPI 1386613065
298 MEMORIAL DR
Seneca, SC 29672
(864) 882-3351
✔ PECOS0.1 mi
Nurse Practitioner
NPI 1093258527
109 OMNI DR STE B
Seneca, SC 29672
(864) 888-4222
✔ PECOS0.2 mi
Certified Registered Nurse Anesthetist (CRNA)
NPI 1104979251
800 NORTH FANT ST
Anderson, SC 29621
(864) 512-1417
✔ Accepts Medicare23 mi
Certified Registered Nurse Anesthetist (CRNA)
NPI 1841346772
1179 MELODY LN
Hartwell, GA 30643
(706) 376-3373
✔ Accepts Medicare24 mi
Certified Registered Nurse Anesthetist (CRNA)
NPI 1497717771
200 FLEETWOOD DRIVE
Easley, SC 29640
(864) 442-7200
✔ Accepts Medicare24 mi
Emergency Medicine
NPI 1861418824
11402 ANDERSON RD
Greenville, SC 29611
(864) 631-2799
✔ PECOS✔ Accepts Medicare29 mi
Family Practice
NPI 1053491209
11402 ANDERSON RD
Greenville, SC 29611
(864) 631-2799
✔ PECOS✔ Accepts Medicare29 mi
Certified Registered Nurse Anesthetist (CRNA)
NPI 1992001374
7 INDEPENDENCE PT STE 300
Greenville, SC 29615
(864) 522-3700
✔ Accepts Medicare30 mi
Nurse Practitioner
NPI 1598012346
48 CENTENNIAL WAY
Greenville, SC 29605
(864) 455-1600
✔ PECOS✔ Accepts Medicare33 mi
Pediatric Medicine
NPI 1174798599
20 MEDICAL RIDGE DR
Greenville, SC 29605
(864) 220-7270
✔ PECOS34 mi
Anesthesiology Assistant
NPI 1114266632
701 GROVE RD
Greenville, SC 29605
(864) 455-3076
34 mi
Hospitalist
NPI 1437108602
701 GROVE RD ER ADMINISTRATION
Greenville, SC 29605
(864) 455-6372
✔ PECOS✔ Accepts Medicare34 mi
Sports Medicine
NPI 1710183694
877 W FARIS RD SUITE A
Greenville, SC 29605
(864) 455-7800
✔ PECOS✔ Accepts Medicare34 mi
Clinical Psychologist
NPI 1003968116
651 S MAIN ST
Greenville, SC 29601
(864) 241-2600
✔ PECOS✔ Accepts Medicare35 mi
Rheumatology
NPI 1114104999
50 INTERNATIONAL DR STE 325
Greenville, SC 29615
(864) 235-8396
✔ PECOS✔ Accepts Medicare39 mi
See all 412 clinicians

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Prisma Health-Upstate's NPI number?

The NPI number for Prisma Health-Upstate is 1821544925. It was assigned to this organization in the NPPES registry on August 29, 2016. The provider is doing business as Prisma Health Cancer Inst-Seneca.

Where is Prisma Health-Upstate located?

Prisma Health-Upstate is located at 131 Lila Doyle Dr, Seneca, SC 29672. The listed phone number is (864) 888-3717.

What is Prisma Health-Upstate's specialty?

The primary specialty registered for this NPI is General Acute Care Hospital with taxonomy code 282N00000X.

Is Prisma Health-Upstate enrolled in Medicare?

Yes. Prisma Health-Upstate is registered in the Medicare PECOS enrollment system.

How many clinicians bill Medicare through Prisma Health-Upstate?

According to the CMS Revalidation Reassignment List (October 2026 release), 412 clinicians in 13 Medicare specialties reassign their Medicare billing to Prisma Health-Upstate. A reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for the clinician's services. The largest specialties are Certified Registered Nurse Anesthetist (CRNA) (267), Emergency Medicine (99) and Nurse Practitioner (20). Of these, 7 practice within 10 miles. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

What insurance does Prisma Health-Upstate accept?

Health plans from Ambetter Health, Ambetter from Absolute Total Care, Ambetter of Alabama, Ambetter of North Carolina and Ambetter of Tennessee and 2 other insurers list Prisma Health-Upstate as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

When was this NPI record last updated?

The NPPES record for Prisma Health-Upstate was last updated on February 5, 2021. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 5 years ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.