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WILLIAM JAMES SAYRE SR. M.D.
NPI 1760478275
Internal Medicine in Lexington, VA

Active since September 21, 2005PECOS EnrolledAccepts Medicare Assignment
108 HOUSTON ST STE A, LEXINGTON, VA 24450(540) 463-2181(540) 463-1125 Get Directions Write a Review

NPPES record last updated: July 8, 2026. Verified against the NPPES registry weekly; last sync: October 25, 2026.

Record update history: Jul 8, 2026, Dec 9, 2020 (2 updates tracked since 2020).

About William James Sayre Sr. M.d. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

WILLIAM JAMES SAYRE SR. M.D. (NPI 1760478275) is an individual internal medicine provider in Lexington, Virginia, licensed in Virginia (0101229127) and active in the NPI registry since September 2005. He is enrolled in Medicare PECOS, is affiliated with University Of Virginia Medical Center, and is a graduate of University Of Virginia School Of Medicine (1996).

NPPES Registry Identity

NPI1760478275
Entity TypeIndividualMale
Primary Taxonomy207R00000X
Provider Legal NameWILLIAM JAMES SAYRE SR.Credential: M.D.
Location Address108 HOUSTON ST STE ALexington, VA 24450-2455
Mailing Address213 S Jefferson St Ste 1006Roanoke, VA 24011-1713 · (540) 224-5516
Phone(540) 463-2181
Fax(540) 463-1125
Sole ProprietorNo
Medical School CMSUniversity Of Virginia School Of MedicineGraduated 1996
Enumeration DateSeptember 21, 2005
Last NPPES UpdateJuly 8, 20262 updates tracked since enumeration
NPPES CertifiedJuly 8, 2026
✔ NPI 1760478275 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyInternal MedicineAllopathic & Osteopathic Physicians
Taxonomy Code207R00000X
License✔ Licensed in VA · 0101229127
Definition
A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults and the elderly. Internists are trained in the diagnosis and treatment of cancer, infections and diseases affecting the heart, blood, kidneys, joints and digestive, respiratory and vascular systems. They are also trained in the essentials of primary care internal medicine, which incorporates an understanding of disease prevention, wellness, substance abuse, mental health and effective treatment of common problems of the eyes, ears, skin, nervous system and reproductive organs.
108 HOUSTON ST STE A, Lexington, VA 24450
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Other Identifiers 5

Medicaid010206766VA
Other110215754VA · Railroad Medicare
Other144808VA · Southren Health Services
Other140212VA · Anthem
Medicaid005824931VA

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

William James Sayre Sr. M.d. is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID5294754701
PECOS Enrollment IDI20051114001133
Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

2

Medicare enrollment records show William Sayre reassigns Medicare billing to 2 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Carilion Rockbridge Community Hospital
Same address
Rural Health
108 HOUSTON ST, SUITE A
Lexington, VA 24450
  • Reassigned Medicare billing, Virginia enrollment
  • Also billed through NPI 1942854427 (Virginia)
  • 507 clinicians in this Medicare group
NPI 1780076265 (540) 458-3344
Carilion Healthcare Corporation
44 mi
Multi-Specialty
213 S JEFFERSON ST STE 1006
Roanoke, VA 24011
  • Reassigned Medicare billing, Virginia enrollment
  • 956 clinicians in this Medicare group
NPI 1447206370 (540) 224-5452

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Hospital Affiliations CMS Care Compare 4

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

University Of Virginia Medical Center

Acute Care Hospitals · Charlottesville, VA
4/5 CMS rating
OwnershipGovernment - State
CMS Certification Number490009
Location1215 Lee StreetCharlottesville, VA 22908 · Charlottesville City County
Emergency services Birthing friendly

Augusta Health

Acute Care Hospitals · Fishersville, VA
4/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number490018
Location78 Medical Center DriveFishersville, VA 22939 · Augusta County
Emergency services Birthing friendly

Carilion Medical Center

Acute Care Hospitals · Roanoke, VA
3/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number490024
Location1906 Belleview Avenue, SERoanoke, VA 24014 · Roanoke City County
Emergency services Birthing friendly

Carilion Stonewall Jackson Hospital

Critical Access Hospitals · Lexington, VA
2/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number491304
Location1 Health CircleLexington, VA 24450 · Lexington City County
Emergency services

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 24450 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient
$129.04 typical visit price
range $56.19 – $170.30
Typical copayment $32.26 (range $14.04 – $42.57)
Most-billed visit code 99204
Established Patient
$99.13 typical visit price
range $18.07 – $138.91
Typical copayment $24.78 (range $4.51 – $34.72)
Most-billed visit code 99214
Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Referred Medical Equipment & Supplies CMS DME claims 14

Durable medical equipment, devices and supplies this provider ordered from DME suppliers for patients, from Medicare fee-for-service claims.

Blood glucose test or reagent strips for home blood glucose monitor, per 50 strips A4253
DME-Other DME · category DE017N
9 suppliers60 claims169 services$6.13 avg. paid by Medicare
Lancets, per box of 100 A4259
DME-Medical/Surgical Supplies · category DA000N
6 suppliers14 claims23 services$1.15 avg. paid by Medicare
Insertion tray with drainage bag with indwelling catheter, foley type, two-way, all silicone A4315
DME-Orthotic Devices · category DF000N
1 supplier12 claims12 services$21.67 avg. paid by Medicare
Bedside drainage bag, day or night, with or without anti-reflux device, with or without tube, each A4357
DME-Orthotic Devices · category DF000N
1 supplier13 claims13 services$8.31 avg. paid by Medicare
Portable gaseous oxygen system, rental; includes portable container, regulator, flowmeter, humidifier, cannula or mask, and tubing E0431
DME-Oxygen and Supplies · category DC000N
2 suppliers70 claims70 services$19.44 avg. paid by Medicare
Stationary oxygen contents, liquid, 1 month's supply = 1 unit E0442
DME-Oxygen and Supplies · category DC000N
1 supplier11 claims11 services$48.18 avg. paid by Medicare
Dollar amounts are the average Medicare paid the supplier per service. They are not the cost to the patient.

Other Providers at the Same Location NPPES 2

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

LEXINGTON INTERNISTS
Specialist
108 HOUSTON ST STE A
LEXINGTON, VA 24450
Lexington City (540) 463-2181
RYAN AUSTIN TOMLIN
Physician Assistant
108 HOUSTON ST STE A
LEXINGTON, VA 24450
Lexington City (540) 463-2181

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is William Sayre's NPI number?

The NPI number for William Sayre is 1760478275. It was assigned to this individual provider in the NPPES registry on September 21, 2005.

Where is William Sayre located?

William Sayre practices at 108 Houston St Ste A, Lexington, VA 24450. The listed phone number is (540) 463-2181.

What is William Sayre's specialty?

The primary specialty registered for this NPI is Internal Medicine with taxonomy code 207R00000X.

Is William Sayre enrolled in Medicare?

Yes. William Sayre is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

Which organizations bill Medicare for William Sayre's services?

According to the CMS Revalidation Reassignment List (October 2026 release), William Sayre reassigns Medicare benefits to 2 organizations: Carilion Rockbridge Community Hospital (Lexington, VA) and Carilion Healthcare Corporation (Roanoke, VA). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for William Sayre's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

Is William Sayre affiliated with any hospitals?

According to CMS data, William Sayre is affiliated with University Of Virginia Medical Center, Augusta Health, Carilion Medical Center and Carilion Stonewall Jackson Hospital.

When was this NPI record last updated?

The NPPES record for William Sayre was last updated on July 8, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 3 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.