MANUEL A SANTIAGO MD
NPI 1760454458
Internal Medicine - Hematology & Oncology in San Antonio, TX

Q: What is the provider's specialty?

The provider's specialty is Internal Medicine with taxonomy code 207RH0003X and a focus in Hematology & Oncology.

Active since February 06, 2006PECOS EnrolledAccepts Medicare Assignment

89.44/100

CMS Quality Rating

5206 RESEARCH DR, SAN ANTONIO, TX 78240(210) 595-5300(210) 614-8740 Get Directions Write a Review

NPPES record last updated: February 26, 2018. Verified against the NPPES registry weekly; last sync: July 19, 2026.

Record update history: Feb 26, 2018, Jan 28, 2016 (2 updates tracked since 2016).

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About Manuel A Santiago Md NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

MANUEL A SANTIAGO MD (NPI 1760454458) is an individual hematology & oncology provider in San Antonio, Texas, licensed in Texas (J7651) and active in the NPI registry since February 2006. He is enrolled in Medicare PECOS, is affiliated with Val Verde Regional Medical Center, and is a graduate of University Of Puerto Rico School Of Medicine (1986).

NPPES Registry Identity

NPI1760454458

Entity TypeIndividualMale

Primary Taxonomy207RH0003X

Provider Legal NameMANUEL A SANTIAGOCredential: MD

Location Address5206 RESEARCH DRSan Antonio, TX 78240-5251

Mailing AddressPo Box 911230Dallas, TX 75391-1230 · (972) 997-8000 · Fax (972) 234-2987

Phone(210) 595-5300

Fax(210) 614-8740

Sole ProprietorNo

Medical School CMSUniversity Of Puerto Rico School Of MedicineGraduated 1986

Enumeration DateFebruary 6, 2006

Last NPPES UpdateFebruary 26, 20182 updates tracked since enumeration

✔ NPI 1760454458 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyInternal Medicine · Hematology & OncologyAllopathic & Osteopathic Physicians

Taxonomy Code207RH0003X

License✔ Licensed in TX · J7651

Definition

An internist doctor of osteopathy that specializes in the treatment of the combination of hematology and oncology disorders. A doctor of osteopathy that is board eligible/certified by the American Osteopathic Board of Internal Medicine WAS able to obtain a Certificate of Special Qualifications in the field of Hematology and Oncology. The Certificate is NO longer offered.

5206 RESEARCH DR, San Antonio, TX 78240

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Other Identifiers 5

Other87982GTX · Bcbs

OtherP01547631TX · Railroad Medicare

Medicaid126541507TX

Medicaid126541506TX

Medicaid126541501TX

Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Ambetter from Arizona Complete Health, Ambetter from Arkansas Health & Wellness, Ambetter from Louisiana Healthcare Connections and more.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, and ordering and referring status from the CMS PECOS system.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Manuel A Santiago Md is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID2466559125

PECOS Enrollment IDI20100329000656

Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Areas of Expertise CMS Part B claims 55

Services this provider delivered to Medicare fee-for-service patients, from the 2024 & 2026 CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Injection, ferumoxytol, for treatment of iron deficiency anemia, 1 mg (non-esrd use) Q0138

Ferumoxytol injection is a treatment for iron deficiency anemia, a condition where your body lacks enough iron. It is injected into your vein to increase iron levels, aiding in the production of healthy red blood cells. This treatment is not for ESRD patients.

8,670 services12 patients

Injection, fosaprepitant, 1 mg J1453

Fosaprepitant is an anti-nausea medication given via injection. It's often used to prevent nausea and vomiting caused by chemotherapy. This injection blocks signals to the brain that trigger these symptoms, helping you feel better.

5,250 services17 patients

Injection, iron sucrose, 1 mg J1756

Iron sucrose injection is a treatment given to replenish iron in your body, often used when oral iron supplements are not effective. This helps your body make red blood cells, improving health and energy levels.

5,100 services15 patients

Injection, darbepoetin alfa, 1 microgram (non-esrd use) J0881

Darbepoetin alfa injection is a medication used to treat anemia (low red blood cell count) often caused by chronic kidney disease or chemotherapy. It works by stimulating your body to produce more red blood cells, helping to increase your energy and well-being.

5,070 services15 patients

Low osmolar contrast material, 300-399 mg/ml iodine concentration, per ml Q9967

Low osmolar contrast material with 300-399 mg/ml iodine concentration is a diagnostic tool used in imaging procedures. It helps to enhance the visibility of specific areas in the body, aiding in accurate diagnosis. It's safe and generally well-tolerated by patients.

4,181 services39 patients

Blood test, comprehensive group of blood chemicals 80053

A comprehensive group of blood chemicals test, also known as a comprehensive metabolic panel, is a blood test that measures your sugar level, electrolyte and fluid balance, kidney function, and liver function. This helps to check your body's overall health.

832 services292 patients

Insertion of needle into vein for collection of blood sample 36415

This procedure involves inserting a small needle into a vein, typically in your arm, to collect a blood sample. It's a quick and simple process to help diagnose or monitor health conditions. You may feel a small prick, but discomfort is minimal.

817 services280 patients

Complete blood cell count (red cells, white blood cell, platelets), automated test and automated differential white blood cell count 85025

A Complete Blood Cell Count is a common test that measures various components of the blood, including red cells (carry oxygen), white cells (fight infection), and platelets (help blood clot). An automated test ensures accuracy. The differential count provides detailed information about white cell types.

800 services291 patients

Injection, dexamethasone sodium phosphate, 1 mg J1100

Dexamethasone sodium phosphate is a medication given via injection. It is a type of steroid that helps reduce inflammation and immune responses. It can be used to treat a variety of conditions, such as allergies, skin conditions, arthritis, and more.

612 services33 patients

Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214

This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.

530 services201 patients

Injection, palonosetron hcl, 25 mcg J2469

Palonosetron HCL is an injection used to prevent nausea and vomiting caused by chemotherapy. It works by blocking a natural substance (serotonin) in the body that can cause vomiting. This helps improve your comfort during cancer treatment.

470 services25 patients

Injection, granisetron hydrochloride, 100 mcg J1626

Granisetron hydrochloride is an anti-nausea medication given by injection. It helps prevent nausea and vomiting often caused by cancer treatments like chemotherapy. Its dosage is measured in micrograms (mcg).

400 services17 patients

Lactate dehydrogenase (enzyme) level 83615

A Lactate Dehydrogenase level test measures the amount of this enzyme in your body. It's often done when tissue damage is suspected, as high levels can indicate issues like heart disease, lung disease, liver disease, or blood disorders. This test helps in diagnosing and monitoring these conditions.

379 services199 patients

Iron binding capacity 83550

Iron binding capacity is a blood test that measures how well your body can bind and transport iron. This helps your healthcare provider assess if your body has too little or too much iron, which can indicate certain health conditions.

305 services135 patients

Ferritin (blood protein) level 82728

A Ferritin level test measures the amount of ferritin, a protein that stores iron, in your blood. It helps determine how much iron your body is storing. If levels are low, it may indicate iron deficiency, while high levels could signify conditions like iron overload.

304 services135 patients

Iron level 83540

An iron level test measures the amount of iron in your blood. Iron is crucial for producing hemoglobin, a protein in red blood cells that carries oxygen throughout your body. This test helps identify iron deficiencies or excesses, which can lead to conditions like anemia or hemochromatosis.

304 services135 patients

Established patient office or other outpatient visit with low level od decision making, if using time, 20 minutes or more 99213

This is a routine visit for patients who have already been seen by the healthcare provider. During this approximately 20-29 minute appointment, your health status will be evaluated and any necessary treatments or tests will be discussed. It's a chance to address any health concerns you may have.

239 services153 patients

Measurement of immunoglobulin light chains 83521

Measurement of immunoglobulin light chains is a blood test that helps to detect and monitor certain disorders related to your immune system. It measures the levels of specific proteins, known as light chains, produced by your immune cells.

210 services63 patients

Gammaglobulin (immune system protein) measurement 82784

Gammaglobulin measurement is a blood test that checks the levels of certain proteins (gammaglobulins) that the body uses to fight infections. High or low levels can indicate various health conditions. It's a simple, quick procedure with minimal discomfort.

176 services32 patients

Subsequent hospital care with moderate levelof medical decision making, if using time, at least 50 minutes 99233

Follow-up hospital inpatient care per day typically involves a 35-minute check-up by your healthcare provider. This service includes monitoring your health progress, adjusting your treatment plan if needed, and answering any questions you may have about your condition or care.

132 services29 patients

Administration of chemotherapy into vein, 1 hour or less 96413

Chemotherapy is a treatment that uses drugs to destroy cancer cells. When administered into a vein, it's often through an IV. This procedure usually lasts 1 hour or less. You may feel a slight pinch as the needle is inserted, but it's generally painless.

129 services61 patients

Red blood count automated, with additional calculations 85046

An automated red blood cell count is a laboratory test that counts the number of red blood cells in your blood. This test also includes additional calculations to measure the size, volume, and hemoglobin concentration of these cells. It helps to identify any abnormalities in your blood.

124 services73 patients

Injection of drug or substance under skin or into muscle 96372

This procedure involves administering medication directly under the skin or into a muscle. A small needle is used to inject the drug, allowing it to be absorbed quickly into the bloodstream. It's a common method for delivering a variety of medications.

116 services45 patients

Infusion into a vein for therapy, prevention, or diagnosis, additional sequential infusion, 1 hour or less 96367

This procedure involves injecting fluids or medication directly into your vein. It's used for treatment, prevention, or diagnosis. An additional sequential infusion may be given within an hour if needed. This helps to ensure the medicine is distributed effectively in your body.

115 services44 patients

Carcinoembryonic antigen (cea) protein level 82378

Carcinoembryonic Antigen (CEA) protein level is a blood test often used in cancer care. It measures the amount of CEA protein in your blood, which can increase in cases of certain types of cancer. It's used to monitor treatment progress and check for cancer recurrence.

93 services24 patients

Injection, zoledronic acid, 1 mg J3489

Zoledronic acid is a medication given via injection to strengthen bones. It's often used in patients with osteoporosis or certain types of cancer. The injection helps reduce the risk of fractures and other bone complications.

89 services14 patients

Reticulated (young) platelet measurement 85055

Reticulated (young) platelet measurement is a blood test that helps determine the number of new platelets your body is producing. It's useful for diagnosing and monitoring conditions affecting platelet production, like anemia or chemotherapy effects.

87 services51 patients

Infusion into a vein for therapy, prevention, or diagnosis, 1 hour or less 96365

This is a procedure where a medical professional inserts a small tube into your vein to deliver medication, nutrients, or fluids directly into your bloodstream. This can be for treatment, prevention, or diagnosis. The process typically takes less than an hour.

81 services46 patients

Injection of additional new drug or substance into vein 96375

This procedure involves introducing a new medication or substance into your bloodstream via a vein. It's typically done using a small needle. The substance can help treat various conditions or assist in diagnostic procedures. It's generally safe and monitored by professionals.

75 services37 patients

Microscopic examination for white blood cells with manual cell count 85007

This is a lab test where a small sample of your blood is studied under a microscope. The goal is to count the number of white blood cells, which are crucial for your body's immune response. The count can help identify potential health issues.

72 services20 patients

Complete blood cell count (red cells, white blood cell, platelets), automated test 85027

A complete blood cell count (CBC) is an automated test that measures different components of the blood, including red cells, white cells, and platelets. It helps assess overall health, detect disorders like anemia or infection, and monitor medical treatments.

72 services20 patients

Blood test, clotting time 85610

A clotting time blood test helps determine how quickly your blood forms clots, a process crucial to stop bleeding. During the test, a small blood sample is taken from your arm. The sample is then analyzed in a lab to see how long it takes for a clot to form.

69 services30 patients

Administration of non-hormonal anti-neoplastic chemotherapy under skin or into muscle 96401

This procedure involves giving anti-cancer drugs, which don't contain hormones, into the muscle or under the skin. These drugs help to stop the growth of cancer cells. The process is usually quick and done by a healthcare professional.

67 services14 patients

Immunologic analysis for detection of tumor antigen, quantitative; ca 15-3 86300

This is a blood test that measures the level of CA 15-3, a protein often higher in individuals with certain types of cancer. It helps monitor response to treatment and check for cancer recurrence. It's not a standalone diagnostic test but used alongside other evaluations.

52 services21 patients

New patient office or other outpatient visit with moderate level of medical decision making, if using time, 45 minutes or more 99204

This is a first-time office or outpatient visit lasting between 45-59 minutes. The healthcare provider evaluates your health, discusses your medical history, and may suggest further tests or treatments. It's an opportunity to ask questions and understand your health better.

50 services50 patients

Radiation treatment delivery,3 or more separate treatment areas, custom blocking, tangential ports, wedges, rotational beam, compensators, electron beam; 11-19 mev G6013

This procedure involves using high-energy radiation to target and treat disease. It covers 3 or more distinct areas, using custom blocks to protect healthy tissue. Tangential ports, wedges, and rotational beams help direct the radiation. An electron beam of 11-19 million electron volts (mev) is used for deep-seated conditions.

48 services23 patients

Beta-2 microglobulin (protein) level 82232

The Beta-2 microglobulin level test measures the amount of this protein in your blood. It's often used to check kidney function or monitor certain cancers. High levels may indicate a health issue. The test involves a simple blood draw.

46 services28 patients

Red blood cell sedimentation rate, to detect inflammation, automated 85652

The Red Blood Cell Sedimentation Rate is a test that helps detect inflammation in the body. It's automated, meaning a machine does the work. This test measures how fast red blood cells settle at the bottom of a tube in an hour. A faster rate may indicate inflammation.

44 services35 patients

Administration of additional new drug or substance into vein, 1 hour or less 96417

This procedure involves introducing a new drug or substance into your vein, typically via an IV drip. It lasts for an hour or less. This method allows the substance to quickly reach your bloodstream, ensuring rapid and effective treatment.

44 services19 patients

Infusion into a vein for therapy, prevention, or diagnosis, each additional hour 96366

This procedure involves delivering medication, fluids, or nutrients directly into your vein. This is done to treat, prevent, or diagnose various conditions. Each additional hour refers to the extended time you may need to receive these substances for optimal results.

41 services13 patients

Coagulation function measurement, d-dimer; quantitative 85379

A quantitative D-dimer test measures the amount of D-dimer, a protein fragment, in your blood. This test helps detect abnormal blood clotting. D-dimer levels can rise in conditions where clots are forming and breaking down, such as deep vein thrombosis or pulmonary embolism.

40 services22 patients

Cyanocobalamin (vitamin b-12) level 82607

A Cyanocobalamin (Vitamin B-12) level test is a blood test that checks the amount of Vitamin B-12 in your body. This vitamin is vital for nerve function and the creation of red blood cells. Low or high levels could indicate a potential health issue.

38 services36 patients

Injection, diphenhydramine hcl, up to 50 mg J1200

Diphenhydramine HCL injection is a medicine given to alleviate symptoms of allergies, colds, or hay fever. It can also help with motion sickness and certain symptoms of Parkinson's disease. Up to 50 mg may be administered depending on your condition.

36 services15 patients

Administration of chemotherapy into vein, each additional hour 96415

Chemotherapy is a treatment method that uses drugs to destroy cancer cells. The drugs are administered into a vein, usually in the arm. Each additional hour of chemotherapy allows for more of the medication to enter your bloodstream to fight against the cancer cells.

35 services17 patients

Established patient office or other outpatient visit with high level of medical decision making, if using time, 40 minutes or more 99215

This service involves a follow-up appointment for existing patients, lasting between 40 to 54 minutes. During this time, your healthcare provider will assess your current health status, discuss any changes or concerns, review your treatment plan, and answer any questions you may have.

32 services21 patients

Intensity modulated treatment delivery, single or multiple fields/arcs,via narrow spatially and temporally modulated beams, binary, dynamic mlc, per treatment session G6015

Intensity-modulated radiation therapy (IMRT) is a type of cancer treatment. It uses advanced technology to manipulate photon beams of radiation to conform to the shape of a tumor. IMRT allows for the radiation dose to conform more precisely to the three-dimensional shape of the tumor by modulatingâ€”or controllingâ€”the intensity of the radiation beam. This can result in better tumor control and less harm to healthy tissue.

31 services19 patients

Infusion into a vein for therapy, prevention, or diagnosis concurrent with another infusion 96368

An infusion into a vein is a method of delivering medication, nutrients, or fluids directly into your bloodstream. If it's concurrent with another infusion, it means two different solutions are given at the same time. This can be for treatment, prevention, or diagnostic purposes.

29 services15 patients

Folic acid level, serum 82746

A Folic Acid Level, Serum test measures the amount of folic acid, a type of B vitamin, in your blood. This vitamin is important for cell growth and development. It's crucial for your body to function well. If your levels are low, it may indicate a deficiency, which can lead to health issues.

28 services27 patients

Irrigation of implanted venous access drug delivery device 96523

Irrigation of an implanted venous access drug delivery device is a procedure to clean or unblock the device. This device is implanted under your skin to allow easy, frequent, and long-term access to your veins for medication delivery. The process involves flushing the device with a sterile solution to ensure it works properly.

28 services17 patients

Ct scan of chest with contrast 71260

A CT scan of the chest with contrast is an imaging procedure. A special dye (contrast) is used to highlight specific areas in your body, providing clearer pictures of your chest. This helps in diagnosing conditions related to your lungs, heart, and other chest structures.

24 services22 patients

Chemotherapy administration, intravenous infusion technique; initiation of infusion in the office/clinic setting using office/clinic pump/supplies, with continuation of the infusion in the community setting (e.g., home, domiciliary, rest home or assisted l G0498

Chemotherapy is a treatment method that uses drugs to destroy cancer cells. In the office, a pump is used to start an intravenous infusion of these drugs. The infusion can then be continued at home or another setting, like a rest home.

23 services11 patients

Ct scan of abdomen with contrast 74160

A CT scan of the abdomen with contrast is a diagnostic procedure. A special dye (contrast) is introduced into your body to highlight certain areas in the images. The CT scanner uses X-rays to create detailed pictures of your abdomen, helping doctors diagnose conditions or monitor treatment.

22 services19 patients

Ct scan of abdomen and pelvis with contrast 74177

A CT scan of the abdomen and pelvis with contrast is an imaging procedure. A special dye, called contrast, is used to make certain areas more visible. This can help identify issues such as infections, tumors, or other abnormalities. The procedure is painless and usually takes about 30 minutes.

20 services19 patients

New patient office or other outpatient visit with a high level of medical decision making, if using time, 60 minutes or more 99205

This is a first-time patient visit where a healthcare professional spends 60-74 minutes with you. It involves a comprehensive evaluation, including your medical history and current health condition. They'll also advise on preventive health measures and formulate a treatment plan if needed.

14 services14 patients

Injection of drug or substance into vein 96374

This procedure involves introducing a medication or substance directly into your vein using a syringe. It's a quick and efficient way to deliver treatment throughout your body. You might feel a small prick when the needle enters. It's generally safe and effective.

11 services11 patients

Hospital Affiliations CMS Care Compare 3

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Val Verde Regional Medical Center

Acute Care Hospitals · Del Rio, TX

OwnershipGovernment - Hospital District or Authority

CMS Certification Number450154

Location801 Bedell AveDel Rio, TX 78840 · Val Verde County

Emergency services

Methodist Hospital

Acute Care Hospitals · San Antonio, TX

4/5 CMS rating

OwnershipProprietary

CMS Certification Number450388

Location7700 Floyd Curl DrSan Antonio, TX 78229 · Bexar County

Emergency services Birthing friendly

Uvalde Memorial Hospital

Critical Access Hospitals · Uvalde, TX

OwnershipGovernment - Hospital District or Authority

CMS Certification Number451387

Location1025 Garner Field RoadUvalde, TX 78801 · Uvalde County

Emergency services

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 78240 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient

$166.88 typical visit price

range $54.84 – $166.88

Typical copayment $41.72 (range $13.71 – $41.72)

Most-billed visit code 99205

Established Patient

$97.05 typical visit price

range $17.52 – $136.11

Typical copayment $24.26 (range $4.38 – $34.02)

Most-billed visit code 99214

Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Medicare Quality Performance CMS QPP · MIPS

Performance in the CMS Quality Payment Program: the MIPS final score across four weighted categories, and the individual quality measures reported to Medicare.

89.44/100

MIPS Final ScoreMerit-based Incentive Payment System · CMS Quality Payment Program

Quality

75.85

Promoting Interoperability

100

Improvement Activities

Other Providers at the Same Location NPPES 20

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

DR. IRENE KAZHDAN M.D.

Internal Medicine (Medical Oncology)