WADE NICOLAS KARAM MD
NPI 1649890732
Orthopaedic Surgery - Orthopaedic Surgery of the Spine in Cypress, TX

Active since April 20, 2020PECOS EnrolledAccepts Medicare Assignment
21216 NORTHWEST FWY STE 620, CYPRESS, TX 77429(281) 807-4380(833) 521-2189 Get Directions Write a Review

NPPES record last updated: July 15, 2026. Verified against the NPPES registry weekly; last sync: October 25, 2026.

Record update history: Jul 15, 2026, Jun 2, 2026, Jun 11, 2025 and 1 more (4 updates tracked since 2020).

About Wade Nicolas Karam Md NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

WADE NICOLAS KARAM MD (NPI 1649890732) is an individual orthopaedic surgery of the spine provider in Cypress, Texas, licensed in Texas (W5399) and active in the NPI registry since April 2020. He is enrolled in Medicare PECOS, is affiliated with Lutheran Hospital, and maintains 3 additional practice locations.

NPPES Registry Identity

NPI1649890732
Entity TypeIndividualMale
Primary Taxonomy207XS0117X
Provider Legal NameWADE NICOLAS KARAMCredential: MD
Location Address21216 NORTHWEST FWY STE 620Cypress, TX 77429-4699
Mailing Address4700 Seton Center Pkwy Ste 115Austin, TX 78759-5753 · (346) 440-0644 · Fax (346) 478-0182
Fax(833) 521-2189
Sole ProprietorYes
Medical School CMSUniversity Of Texas Medical Branch At GalvestonGraduated 2020
Enumeration DateApril 20, 2020
Last NPPES UpdateJuly 15, 20264 updates tracked since enumeration
NPPES CertifiedJuly 15, 2026
✔ NPI 1649890732 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses 2

★ Primary SpecialtyOrthopaedic Surgery · Orthopaedic Surgery of the SpineAllopathic & Osteopathic Physicians
Taxonomy Code207XS0117X
License✔ Licensed in TX · W5399
Definition
Recognized by several state medical boards as a fellowship subspecialty program of orthopaedic surgery, orthopaedic surgeons of the spine deal with the evaluation and nonoperative and operative treatment of the full spectrum of primary spinal disorders including trauma, degenerative, deformity, tumor, and reconstructive.
Also ListedOrthopaedic SurgeryTaxonomy 207X00000X · License W5399 (TX), 35.153326 (OH)
21216 NORTHWEST FWY STE 620, Cypress, TX 77429

Secondary Practice Locations 3

Location 126400 Kuykendahl Rd Ste A250Tomball, TX 77375-2984 · Phone (281) 407-5092 · Fax (833) 764-5063
Location 27401 Main StHouston, TX 77030-4509 · Phone (713) 799-2300 · Fax (833) 520-1440
Location 38731 Katy Fwy Ste 110Houston, TX 77024-1735 · Phone (832) 516-6997 · Fax (833) 972-5137

Group Practice 1

Group TaxonomyThis provider is a business group of one or more individual practitioners, who practice with different areas of specialization.193200000X MULTI-SPECIALTY GROUP

Accepted Insurance

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Wade Nicolas Karam Md is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID8628584604
PECOS Enrollment IDI20250822002280, I20260608001061
Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

2

Medicare enrollment records show Wade Karam reassigns Medicare billing to 2 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Orthopaedic Surgery
7401 MAIN ST
Houston, TX 77030
  • Reassigned Medicare billing, Texas enrollment
  • 327 clinicians in this Medicare group
Family Medicine
36040 DETROIT RD, STE A
Avon, OH 44011
  • Reassigned Medicare billing, Ohio enrollment
  • 7,608 clinicians in this Medicare group

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Hospital Affiliations CMS Care Compare 4

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Lutheran Hospital

Acute Care Hospitals · Cleveland, OH
3/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number360087
Location1730 West 25th StreetCleveland, OH 44113 · Cuyahoga County
Emergency services

Cleveland Clinic

Acute Care Hospitals · Cleveland, OH
5/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number360180
Location9500 Euclid AvenueCleveland, OH 44195 · Cuyahoga County
Emergency services Birthing friendly

Hillcrest Hospital

Acute Care Hospitals · Mayfield Heights, OH
4/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number360230
Location6780 Mayfield RoadMayfield Heights, OH 44124 · Cuyahoga County
Birthing friendly

Texas Orthopedic Hospital

Acute Care Hospitals · Houston, TX
OwnershipVoluntary non-profit - Other
CMS Certification Number450804
Location7401 South Main StreetHouston, TX 77030 · Harris County
Emergency services

Other Providers at the Same Location NPPES 7

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

Physical Therapist (Orthopedic)
21216 NORTHWEST FWY STE 620
CYPRESS, TX 77429
Physical Therapy Assistant
21216 NORTHWEST FWY STE 620
CYPRESS, TX 77429
Family Medicine (Sports Medicine)
21216 NORTHWEST FWY STE 620
CYPRESS, TX 77429
Orthopaedic Surgery
21216 NORTHWEST FWY STE 620
CYPRESS, TX 77429
Family Medicine
21216 NORTHWEST FWY STE 620
CYPRESS, TX 77429
Orthopaedic Surgery (Sports Medicine)
21216 NORTHWEST FWY STE 620
CYPRESS, TX 77429
Physical Therapy Assistant
21216 NORTHWEST FWY STE 620
CYPRESS, TX 77429

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Wade Karam's NPI number?

The NPI number for Wade Karam is 1649890732. It was assigned to this individual provider in the NPPES registry on April 20, 2020.

Where is Wade Karam located?

Wade Karam practices at 21216 Northwest Fwy Ste 620, Cypress, TX 77429. The listed phone number is (281) 807-4380.

What is Wade Karam's specialty?

The primary specialty registered for this NPI is Orthopaedic Surgery, specializing in Orthopaedic Surgery of the Spine, with taxonomy code 207XS0117X.

Is Wade Karam enrolled in Medicare?

Yes. Wade Karam is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

Which organizations bill Medicare for Wade Karam's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Wade Karam reassigns Medicare benefits to 2 organizations: Ortholonestar, PLLC (Houston, TX) and The Cleveland Clinic Foundation (Avon, OH). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Wade Karam's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

What insurance does Wade Karam accept?

Health plans from Ambetter from Arizona Complete Health, Ambetter from Arkansas Health & Wellness, Ambetter from Louisiana Healthcare Connections, Ambetter from Superior HealthPlan and Ambetter of Oklahoma list Wade Karam as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Wade Karam affiliated with any hospitals?

According to CMS data, Wade Karam is affiliated with Lutheran Hospital, Cleveland Clinic, Hillcrest Hospital and Texas Orthopedic Hospital.

When was this NPI record last updated?

The NPPES record for Wade Karam was last updated on July 15, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 3 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.