DR. MATTHEW SHUPE D.O.
NPI 1629206750
Internal Medicine - Hematology & Oncology in Lincoln, NE

Active since June 27, 2009PECOS EnrolledAccepts Medicare Assignment
4004 PIONEER WOODS DR, LINCOLN, NE 68506(402) 484-4900(402) 484-6456 Get Directions Write a Review

NPPES record last updated: December 31, 2025. Verified against the NPPES registry weekly; last sync: August 02, 2026.

Record update history: Dec 31, 2025, Jun 24, 2025, May 1, 2023 and 3 more (6 updates tracked since 2018).

About Dr. Matthew Shupe D.o. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

DR. MATTHEW SHUPE D.O. (NPI 1629206750) is an individual hematology & oncology provider in Lincoln, Nebraska, licensed in South Dakota (10248) and active in the NPI registry since June 2009. He is enrolled in Medicare PECOS, is affiliated with Bryan Medical Center, and maintains a secondary practice location in Lincoln.

NPPES Registry Identity

NPI1629206750
Entity TypeIndividualMale
Primary Taxonomy207RH0003X
Provider Legal NameDR. MATTHEW SHUPECredential: D.O.
Location Address4004 PIONEER WOODS DRLincoln, NE 68506-7548
Mailing Address4004 Pioneer Woods DrLincoln, NE 68506-7548 · (402) 484-4900 · Fax (402) 484-6456
Fax(402) 484-6456
Sole ProprietorYes
Medical School CMSOtherGraduated 2009
Enumeration DateJune 27, 2009
Last NPPES UpdateDecember 31, 20256 updates tracked since enumeration
NPPES CertifiedDecember 31, 2025
NPI 1629206750 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

Primary SpecialtyInternal Medicine · Hematology & OncologyAllopathic & Osteopathic Physicians
Taxonomy Code207RH0003X
Licenses Licensed in SD · 10248 Licensed in NE · 788
Definition
An internist doctor of osteopathy that specializes in the treatment of the combination of hematology and oncology disorders. A doctor of osteopathy that is board eligible/certified by the American Osteopathic Board of Internal Medicine WAS able to obtain a Certificate of Special Qualifications in the field of Hematology and Oncology. The Certificate is NO longer offered.
4004 PIONEER WOODS DR, Lincoln, NE 68506

Secondary Practice Location 1

Location 14001 Pioneer Woods DrLincoln, NE 68506-7547 · Phone (402) 484-4900 · Fax (402) 484-6456

Accepted Insurance

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, and ordering and referring status from the CMS PECOS system.

Medicare Enrollment Status

Enrolled in Medicare and accepts Medicare assignment

Dr. Matthew Shupe D.o. is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID4880989359
PECOS Enrollment IDI20170502000646, I20181106002571
Eligible to Order & Refer Part B Labs & Imaging Durable Medical Equipment Home Health Agency Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Areas of Expertise CMS Part B claims 73

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Injection, ferric carboxymaltose, 1 mg J1439
Ferric carboxymaltose is an iron supplement injection. It's given when your body needs more iron than you can consume through diet, like in anemia. The injection is administered by a healthcare professional into a vein.
28,350 services33 patients
Injection, pembrolizumab, 1 mg J9271
Pembrolizumab is a medication given via injection to help your body's immune system fight certain types of cancer. It's typically administered in a hospital or clinic by a healthcare professional.
11,000 services25 patients
Injection, aprepitant, 1 mg J0185
Aprepitant injection is a medication used to prevent nausea and vomiting caused by chemotherapy. It works by blocking certain substances in the brain that trigger these symptoms. The dosage is based on your medical condition and response to treatment.
9,360 services39 patients
Injection, oxaliplatin, 0.5 mg J9263
Oxaliplatin is a chemotherapy drug that is administered via injection. It works by stopping cancer cells from growing and dividing, which helps in the treatment of certain types of cancer. The dosage is 0.5 mg, and it's important to follow your doctor's instructions for this treatment.
8,340 services15 patients
Injection, denosumab, 1 mg J0897
Denosumab is a medication given via injection to strengthen your bones. It works by slowing down the cells that break down bone, improving bone density and reducing the risk of fractures. It's often used for osteoporosis treatment.
7,320 services32 patients
Injection, daratumumab, 10 mg and hyaluronidase-fihj J9144
Daratumumab and hyaluronidase-fihj is an injection administered to treat certain types of blood cancer. The medication works by targeting and killing specific cancer cells. It's often given under the skin to reduce side effects and improve patient comfort.
6,660 services17 patients

Hospital Affiliations CMS Care Compare 5

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Bryan Medical Center

Acute Care Hospitals · Lincoln, NE
4/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number280003
Location1600 South 48th StLincoln, NE 68506 · Lancaster County
Emergency services Birthing friendly

The Nebraska Medical Center

Acute Care Hospitals · Omaha, NE
3/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number280013
Location987400 Nebraska Medical CenterOmaha, NE 68198 · Douglas County
Emergency services Birthing friendly

Great Plains Health

Acute Care Hospitals · North Platte, NE
2/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number280065
Location601 West Leota StNorth Platte, NE 69101 · Lincoln County
Emergency services Birthing friendly

Jefferson Community Health & Life

Critical Access Hospitals · Fairbury, NE
OwnershipVoluntary non-profit - Private
CMS Certification Number281319
LocationP O Box 277, 2200 H StFairbury, NE 68352 · Jefferson County
Emergency services

Nemaha County Hospital

Critical Access Hospitals · Auburn, NE
OwnershipGovernment - Local
CMS Certification Number281324
Location2022 13th StreetAuburn, NE 68305 · Nemaha County
Emergency services

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 68506 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient
$160.21 typical visit price
range $52.69 – $160.21
Typical copayment $40.05 (range $13.17 – $40.05)
Most-billed visit code 99205
Established Patient
$93.55 typical visit price
range $16.90 – $131.25
Typical copayment $23.38 (range $4.22 – $32.81)
Most-billed visit code 99214
Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Other Providers at the Same Location NPPES 20

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

Family Medicine (Hospice and Palliative Medicine)
4004 PIONEER WOODS DR
LINCOLN, NE 68506
Registered Nurse (Oncology)
4004 PIONEER WOODS DR
LINCOLN, NE 68506
Physician Assistant
4004 PIONEER WOODS DR
LINCOLN, NE 68506
Physician Assistant
4004 PIONEER WOODS DR
LINCOLN, NE 68506
Internal Medicine (Hematology & Oncology)
4004 PIONEER WOODS DR
LINCOLN, NE 68506
Registered Nurse (Oncology)
4004 PIONEER WOODS DR
LINCOLN, NE 68506
Registered Nurse (Oncology)
4004 PIONEER WOODS DR
LINCOLN, NE 68506
Physician Assistant (Medical)
4004 PIONEER WOODS DR
LINCOLN, NE 68506

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Matthew Shupe's NPI number?

The NPI number for Matthew Shupe is 1629206750. It was assigned to this individual provider in the NPPES registry on June 27, 2009.

Where is Matthew Shupe located?

Matthew Shupe practices at 4004 Pioneer Woods Dr, Lincoln, NE 68506. The listed phone number is (402) 484-4900.

What is Matthew Shupe's specialty?

The primary specialty registered for this NPI is Internal Medicine, specializing in Hematology & Oncology, with taxonomy code 207RH0003X.

Is Matthew Shupe enrolled in Medicare?

Yes. Matthew Shupe is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

What insurance does Matthew Shupe accept?

Health plans from Ambetter Health, Ambetter Health of Delaware, Ambetter from Home State Health, Ambetter from Sunflower Health Plan and Blue Cross Blue Shield of North Dakota and 4 other insurers list Matthew Shupe as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Matthew Shupe affiliated with any hospitals?

According to CMS data, Matthew Shupe is affiliated with Bryan Medical Center, The Nebraska Medical Center, Great Plains Health, Jefferson Community Health & Life and Nemaha County Hospital.

When was this NPI record last updated?

The NPPES record for Matthew Shupe was last updated on December 31, 2025. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 7 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.