Recently Updated NPI Information — some details in this NPI profile have been updated in the NPI registry within the last 60 days.

MRS. SHAYLA MARIE HOLYOKE ACNP
NPI 1588358253
Nurse Practitioner - Acute Care in Phoenix, AZ

Active since June 06, 2023PECOS Enrolled
500 W THOMAS RD STE 850, PHOENIX, AZ 85013(602) 406-1150(602) 406-1159 Get Directions Write a Review

NPPES record last updated: October 15, 2026. Verified against the NPPES registry weekly; last sync: October 18, 2026.

Record update history: Oct 15, 2026, Dec 6, 2024, Sep 5, 2023 and 2 more (5 updates tracked since 2023).

About Mrs. Shayla Marie Holyoke Acnp NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

MRS. SHAYLA MARIE HOLYOKE ACNP (NPI 1588358253) is an individual acute care provider in Phoenix, Arizona, licensed in Arizona (293467) and active in the NPI registry since June 2023. She is enrolled in Medicare PECOS and maintains a secondary practice location in Phoenix.

NPPES Registry Identity

NPI1588358253
Entity TypeIndividualFemale
Primary Taxonomy363LA2100X
Provider Legal NameMRS. SHAYLA MARIE HOLYOKECredential: ACNP
Location Address500 W THOMAS RD STE 850Phoenix, AZ 85013-4218
Mailing AddressPo Box 33269Phoenix, AZ 85067-3269 · (602) 406-4786 · Fax (916) 636-4358
Fax(602) 406-1159
Sole ProprietorYes
Enumeration DateJune 6, 2023
Last NPPES UpdateOctober 15, 20265 updates tracked since enumeration
NPPES CertifiedOctober 15, 2026
✔ NPI 1588358253 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses 2

★ Primary SpecialtyNurse Practitioner · Acute CarePhysician Assistants & Advanced Practice Nursing Providers
Taxonomy Code363LA2100X
License✔ Licensed in AZ · 293467
Also ListedNurse PractitionerTaxonomy 363L00000X · License 293467 (AZ)
500 W THOMAS RD STE 850, Phoenix, AZ 85013

Secondary Practice Location 1

Location 13141 N 3rd Ave Ste 140Phoenix, AZ 85013-4360 · Phone (602) 406-1150 · Fax (602) 406-1159

Accepted Insurance

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare (PECOS)

Mrs. Shayla Marie Holyoke Acnp is registered in the CMS Provider Enrollment, Chain and Ownership System (PECOS).

Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

2

Medicare enrollment records show Shayla Holyoke reassigns Medicare billing to 2 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Multi-Specialty
350 W THOMAS RD
Phoenix, AZ 85013
  • Reassigned Medicare billing, Arizona enrollment
  • 773 clinicians in this Medicare group
Pulmonary Disease
9250 N 3RD ST STE 2035
Phoenix, AZ 85020
  • Reassigned Medicare billing, Arizona enrollment
  • 13 clinicians in this Medicare group

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 85013 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient
$85.89 typical visit price
range $55.44 – $168.60
Typical copayment $21.47 (range $13.86 – $42.15)
Most-billed visit code 99203
Established Patient
$98.00 typical visit price
range $17.72 – $137.41
Typical copayment $24.50 (range $4.43 – $34.35)
Most-billed visit code 99214
Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Other Providers at the Same Location NPPES 20

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

Nurse Practitioner (Acute Care)
500 W THOMAS RD STE 850
PHOENIX, AZ 85013
Nurse Practitioner (Adult Health)
500 W THOMAS RD STE 850
PHOENIX, AZ 85013
Internal Medicine (Interventional Cardiology)
500 W THOMAS RD STE 850
PHOENIX, AZ 85013
Internal Medicine (Cardiovascular Disease)
500 W THOMAS RD STE 850
PHOENIX, AZ 85013
Internal Medicine (Cardiovascular Disease)
500 W THOMAS RD STE 850
PHOENIX, AZ 85013
Nurse Practitioner (Adult Health)
500 W THOMAS RD STE 850
PHOENIX, AZ 85013
Internal Medicine (Interventional Cardiology)
500 W THOMAS RD STE 850
PHOENIX, AZ 85013
Internal Medicine (Cardiovascular Disease)
500 W THOMAS RD STE 850
PHOENIX, AZ 85013

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Shayla Holyoke's NPI number?

The NPI number for Shayla Holyoke is 1588358253. It was assigned to this individual provider in the NPPES registry on June 6, 2023.

Where is Shayla Holyoke located?

Shayla Holyoke practices at 500 W Thomas Rd Ste 850, Phoenix, AZ 85013. The listed phone number is (602) 406-1150.

What is Shayla Holyoke's specialty?

The primary specialty registered for this NPI is Nurse Practitioner, specializing in Acute Care, with taxonomy code 363LA2100X.

Is Shayla Holyoke enrolled in Medicare?

Yes. Shayla Holyoke is registered in the Medicare PECOS enrollment system.

Which organizations bill Medicare for Shayla Holyoke's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Shayla Holyoke reassigns Medicare benefits to 2 organizations: Sjhmc Physician Services (Phoenix, AZ) and Maricopa Pulmonary Consultants LLC (Phoenix, AZ). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Shayla Holyoke's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

What insurance does Shayla Holyoke accept?

Health plans from Cigna HealthCare of Arizona, Inc and UnitedHealthcare list Shayla Holyoke as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

When was this NPI record last updated?

The NPPES record for Shayla Holyoke was last updated on October 15, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 10 days ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.