IRENE-MARGARETTE LOUIS SPANOS APRN
NPI 1457027682
Nurse Practitioner - Family in Mount Pleasant, SC
About Irene-margarette Louis Spanos Aprn NPPES
Official registry information on file with the National Plan and Provider Enumeration System.
IRENE-MARGARETTE LOUIS SPANOS APRN (NPI 1457027682) is an individual family provider in Mount Pleasant, South Carolina, licensed in South Carolina (25245) and active in the NPI registry since August 2021. She is enrolled in Medicare PECOS, is affiliated with Trident Medical Center, and is a graduate of Other (2021).
NPPES Registry Identity
Specialties & Licenses
Accepted Insurance
Medicare Participation & PECOS CMS
Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.
Medicare Enrollment Status
Enrolled in Medicare and accepts Medicare assignment
Irene-margarette Louis Spanos Aprn is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.
Medicare Billing Reassignments
4Medicare enrollment records show Irene-margarette Spanos reassigns Medicare billing to 4 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.
Mt Pleasant, SC 29464
- Reassigned Medicare billing, South Carolina enrollment
- 290 clinicians in this Medicare group
Simpsonville, SC 29680
- Reassigned Medicare billing, South Carolina enrollment
- 176 clinicians in this Medicare group
Simpsonville, SC 29680
- Reassigned Medicare billing, South Carolina enrollment
- 112 clinicians in this Medicare group
Dallas, TX 75244
- Reassigned Medicare billing, South Carolina enrollment
- 311 clinicians in this Medicare group
Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.
Areas of Expertise CMS Part B claims 10
Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.
Hospital Affiliations CMS Care Compare 2
Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.
Trident Medical Center
Acute Care Hospitals · Charleston, SCMount Pleasant Hospital
Acute Care Hospitals · Mount Pleasant, SCPhysician Visit Costs CMS claims · ZIP area
Typical Medicare office-visit costs in the 29464 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.
Other Providers at the Same Location NPPES 19
Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.
MOUNT PLEASANT, SC 29464
MOUNT PLEASANT, SC 29464
Frequently Asked Questions NPPES & CMS
Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.
What is Irene-margarette Spanos's NPI number?
The NPI number for Irene-margarette Spanos is 1457027682. It was assigned to this individual provider in the NPPES registry on August 18, 2021.
Where is Irene-margarette Spanos located?
Irene-margarette Spanos practices at 1676 N Highway 17, Mount Pleasant, SC 29464. The listed phone number is (860) 941-5976.
What is Irene-margarette Spanos's specialty?
The primary specialty registered for this NPI is Nurse Practitioner, specializing in Family, with taxonomy code 363LF0000X.
Is Irene-margarette Spanos enrolled in Medicare?
Yes. Irene-margarette Spanos is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.
Which organizations bill Medicare for Irene-margarette Spanos's services?
According to the CMS Revalidation Reassignment List (October 2026 release), Irene-margarette Spanos reassigns Medicare benefits to 4 organizations: Palmetto Primary Care Physicians, LLC (Mt Pleasant, SC), Minuteclinic Diagnostic South Carolina LLC (Simpsonville, SC), Minuteclinic Primary Care South Carolina LLC (Simpsonville, SC) and Signify Health Medical Associates, PLLC (Dallas, TX). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Irene-margarette Spanos's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.
What insurance does Irene-margarette Spanos accept?
Health plans from Ambetter Health, Ambetter from Absolute Total Care, Ambetter of North Carolina, First Choice Next and Molina Healthcare list Irene-margarette Spanos as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.
Is Irene-margarette Spanos affiliated with any hospitals?
According to CMS data, Irene-margarette Spanos is affiliated with Trident Medical Center and Mount Pleasant Hospital.
When was this NPI record last updated?
The NPPES record for Irene-margarette Spanos was last updated on March 17, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 7 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.
# Irene-Margarette Louis Spanos, APRN · NPI 1457027682
Family physician in Mount Pleasant, South Carolina. Individual provider, active in the CMS NPPES registry since August 18, 2021.
## Identity
- **NPI:** 1457027682 (Entity type: Individual)
- **Enumerated:** August 18, 2021
- **Primary specialty:** Nurse Practitioner - Family · taxonomy 363LF0000X
- **State license:** 25245 (South Carolina)
- **Sole proprietor:** No
## Practice location
- **Address:** 1676 N HIGHWAY 17, Mount Pleasant, SC 29464-3310
- **Phone:** (860) 941-5976
## Medicare
- **Medicare:** Enrolled (PECOS); accepts Medicare assignment
- **Ordering & referring:** eligible for Part B labs & imaging, durable medical equipment, home health, power mobility devices
- **Bills Medicare through:** 4 organizations under Medicare reassignment (form CMS-855R): Palmetto Primary Care Physicians, LLC (NPI 1487058244, Mt Pleasant, SC); Minuteclinic Diagnostic South Carolina LLC (NPI 1447420815, Simpsonville, SC); Minuteclinic Primary Care South Carolina LLC (NPI 1548070071, Simpsonville, SC); Signify Health Medical Associates, PLLC (NPI 1750845863, Dallas, TX) · CMS Revalidation Reassignment List, October 2026 release
- **Medical school:** Other, class of 2021
## Record status
- **NPPES last updated:** March 17, 2026
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Source: [NPI Profile](https://npiprofile.com/npi/1457027682) · Data from the CMS NPPES public registry.