RAYMOND M ESPER MD
NPI 1407085376
Internal Medicine - Medical Oncology in Fort Myers, FL

Q: What is the provider's specialty?

The provider's specialty is Internal Medicine with taxonomy code 207RX0202X and a focus in Medical Oncology.

Active since July 13, 2009PECOS EnrolledAccepts Medicare Assignment

75/100

CMS Quality Rating

8260 GLADIOLUS DR, FORT MYERS, FL 33908(239) 437-5755(239) 437-5776 Get Directions Write a Review

NPPES record last updated: February 17, 2026. Verified against the NPPES registry weekly; last sync: July 19, 2026.

Record update history: May 2, 2022, Nov 8, 2021, Jul 12, 2016 (3 updates tracked since 2016).

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About Raymond M Esper Md NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

RAYMOND M ESPER MD (NPI 1407085376) is an individual medical oncology provider in Fort Myers, Florida, licensed in Florida (ME126015) and active in the NPI registry since July 2009. He is enrolled in Medicare PECOS, is affiliated with Lee Memorial Hospital, and maintains 2 additional practice locations.

NPPES Registry Identity

NPI1407085376

Entity TypeIndividualMale

Primary Taxonomy207RX0202X

Provider Legal NameRAYMOND M ESPERCredential: MD

Location Address8260 GLADIOLUS DRFort Myers, FL 33908-4156

Mailing AddressPo Box 102222, Attn: Credentialing DeptAtlanta, GA 30368-2222 · (239) 274-8200

Phone(239) 437-5755

Fax(239) 437-5776

Sole ProprietorNo

Medical School CMSWayne State University School Of MedicineGraduated 2009

Enumeration DateJuly 13, 2009

Last NPPES UpdateFebruary 17, 20263 updates tracked since enumeration

NPPES CertifiedFebruary 17, 2026

✔ NPI 1407085376 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses 2

★ Primary SpecialtyInternal Medicine · Medical OncologyAllopathic & Osteopathic Physicians

Taxonomy Code207RX0202X

License✔ Licensed in FL · ME126015

Definition

An internist who specializes in the diagnosis and treatment of all types of cancer and other benign and malignant tumors. This specialist decides on and administers therapy for these malignancies as well as consults with surgeons and radiotherapists on other treatments for cancer.

Also ListedInternal Medicine · HematologyTaxonomy 207RH0000X · License ME126015 (FL)

8260 GLADIOLUS DR, Fort Myers, FL 33908

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Secondary Practice Locations 2

Location 11030 Commerce Creek BlvdCape Coral, FL 33909-6529 · Phone (239) 997-3081 · Fax (844) 862-7077

Location 21708 Cape Coral Pkwy W Ste 10Cape Coral, FL 33914-6985 · Phone (239) 541-4633 · Fax (866) 504-2990

Other Identifiers 1

Medicaid016931400FL

Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Ambetter Health, Ambetter of Alabama, AvMed and more.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, and ordering and referring status from the CMS PECOS system.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Raymond M Esper Md is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID5193955409

PECOS Enrollment IDI20160419002898

Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Areas of Expertise CMS Part B claims 61

Services this provider delivered to Medicare fee-for-service patients, from the 2024 & 2026 CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Injection, ferumoxytol, for treatment of iron deficiency anemia, 1 mg (non-esrd use) Q0138

Ferumoxytol injection is a treatment for iron deficiency anemia, a condition where your body lacks enough iron. It is injected into your vein to increase iron levels, aiding in the production of healthy red blood cells. This treatment is not for ESRD patients.

97,410 services85 patients

Injection, pembrolizumab, 1 mg J9271

Pembrolizumab is a medication given via injection to help your body's immune system fight certain types of cancer. It's typically administered in a hospital or clinic by a healthcare professional.

18,200 services25 patients

Injection, nivolumab, 1 mg J9299

Nivolumab is a medication given via injection, often used in cancer treatment. It works by helping your immune system fight the cancer cells. The dosage is measured in milligrams (mg), with 1 mg being a common dose.

17,740 services11 patients

Injection, epoetin alfa, (for non-esrd use), 1000 units J0885

Epoetin alfa is a medication injected to help your body produce more red blood cells, improving energy levels and reducing tiredness. It's often used for patients with certain types of anemia. Each injection contains 1000 units of the medicine.

15,130 services77 patients

Injection, azacitidine, 1 mg J9025

Azacitidine is a medication administered via injection to treat certain types of blood or bone marrow cancer. This drug works by slowing or stopping the growth of cancer cells. It's typically given in a clinic or hospital setting by a healthcare professional.

14,700 services14 patients

Injection, iron sucrose, 1 mg J1756

Iron sucrose injection is a treatment given to replenish iron in your body, often used when oral iron supplements are not effective. This helps your body make red blood cells, improving health and energy levels.

8,800 services28 patients

Injection, daratumumab, 10 mg and hyaluronidase-fihj J9144

Daratumumab and hyaluronidase-fihj is an injection administered to treat certain types of blood cancer. The medication works by targeting and killing specific cancer cells. It's often given under the skin to reduce side effects and improve patient comfort.

7,740 services17 patients

Injection, denosumab, 1 mg J0897

Denosumab is a medication given via injection to strengthen your bones. It works by slowing down the cells that break down bone, improving bone density and reducing the risk of fractures. It's often used for osteoporosis treatment.

7,500 services58 patients

Injection, aprepitant, 1 mg J0185

Aprepitant injection is a medication used to prevent nausea and vomiting caused by chemotherapy. It works by blocking certain substances in the brain that trigger these symptoms. The dosage is based on your medical condition and response to treatment.

6,110 services21 patients

Injection, epoetin alfa-epbx, biosimilar, (retacrit) (for non-esrd use), 1000 units Q5106

Epoetin alfa-epbx (Retacrit) is a biosimilar injection used for non-ESRD (End-Stage Renal Disease). It helps your body make more red blood cells, increasing your energy and well-being. It's usually given under the skin or into a vein by a healthcare professional.

4,630 services16 patients

Injection, paclitaxel, 1 mg J9267

Paclitaxel is a medication administered via injection to treat various types of cancer. It works by inhibiting cell division, thus preventing cancer cells from growing and multiplying. Each dose is tailored to the patient's body size.

4,586 services13 patients

Injection, dexamethasone sodium phosphate, 1 mg J1100

Dexamethasone sodium phosphate is a medication given via injection. It is a type of steroid that helps reduce inflammation and immune responses. It can be used to treat a variety of conditions, such as allergies, skin conditions, arthritis, and more.

3,188 services79 patients

Injection, immune globulin, (gammagard liquid), non-lyophilized, (e.g., liquid), 500 mg J1569

The Gammagard Liquid injection is a type of immune globulin therapy. It's used to boost your body's immune system, helping it fight off infections. The therapy involves injecting a liquid form of proteins, collected from healthy donors, into your body. This is a 500mg dose.

2,854 services12 patients

Complete blood cell count (red cells, white blood cell, platelets), automated test and automated differential white blood cell count 85025

A Complete Blood Cell Count is a common test that measures various components of the blood, including red cells (carry oxygen), white cells (fight infection), and platelets (help blood clot). An automated test ensures accuracy. The differential count provides detailed information about white cell types.

2,762 services957 patients

Insertion of needle into vein for collection of blood sample 36415

This procedure involves inserting a small needle into a vein, typically in your arm, to collect a blood sample. It's a quick and simple process to help diagnose or monitor health conditions. You may feel a small prick, but discomfort is minimal.

2,538 services947 patients

Injection, rituximab-arrx, biosimilar, (riabni), 10 mg Q5123

Rituximab-arrx (Riabni) is a biosimilar medicine administered via injection. It's used to treat certain autoimmune diseases and types of cancer. This therapy works by targeting specific cells, helping your body's immune system fight disease.

2,228 services14 patients

Injection, infliximab, excludes biosimilar, 10 mg J1745

Infliximab is a medication given via injection to treat certain autoimmune conditions. It works by blocking the action of a substance in your body that causes inflammation. Each dose is based on your medical condition and response to treatment.

1,900 services11 patients

Injection, palonosetron hcl, 25 mcg J2469

Palonosetron HCL is an injection used to prevent nausea and vomiting caused by chemotherapy. It works by blocking a natural substance (serotonin) in the body that can cause vomiting. This helps improve your comfort during cancer treatment.

1,300 services47 patients

Red blood count automated, with additional calculations 85046

An automated red blood cell count is a laboratory test that counts the number of red blood cells in your blood. This test also includes additional calculations to measure the size, volume, and hemoglobin concentration of these cells. It helps to identify any abnormalities in your blood.

1,288 services375 patients

Injection of drug or substance under skin or into muscle 96372

This procedure involves administering medication directly under the skin or into a muscle. A small needle is used to inject the drug, allowing it to be absorbed quickly into the bloodstream. It's a common method for delivering a variety of medications.

1,171 services287 patients

Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214

This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.

1,084 services504 patients

Injection, ondansetron hydrochloride, per 1 mg J2405

Ondansetron hydrochloride is a medication given via injection to help prevent nausea and vomiting, often due to chemotherapy or surgery. It works by blocking certain chemicals in the body that trigger these symptoms.

680 services28 patients

Established patient office or other outpatient visit with low level od decision making, if using time, 20 minutes or more 99213

This is a routine visit for patients who have already been seen by the healthcare provider. During this approximately 20-29 minute appointment, your health status will be evaluated and any necessary treatments or tests will be discussed. It's a chance to address any health concerns you may have.

644 services437 patients

Injection of additional new drug or substance into vein 96375

This procedure involves introducing a new medication or substance into your bloodstream via a vein. It's typically done using a small needle. The substance can help treat various conditions or assist in diagnostic procedures. It's generally safe and monitored by professionals.

642 services132 patients

Established patient office or other outpatient visit with high level of medical decision making, if using time, 40 minutes or more 99215

This service involves a follow-up appointment for existing patients, lasting between 40 to 54 minutes. During this time, your healthcare provider will assess your current health status, discuss any changes or concerns, review your treatment plan, and answer any questions you may have.

633 services206 patients

Administration of chemotherapy into vein, 1 hour or less 96413

Chemotherapy is a treatment that uses drugs to destroy cancer cells. When administered into a vein, it's often through an IV. This procedure usually lasts 1 hour or less. You may feel a slight pinch as the needle is inserted, but it's generally painless.

517 services142 patients

Injection, vitamin b-12 cyanocobalamin, up to 1000 mcg J3420

This is a procedure where a small dose of Vitamin B-12, also known as Cyanocobalamin, is injected into your body. This vitamin is essential for nerve function and the production of red blood cells. It's often used to treat vitamin B-12 deficiency.

409 services104 patients

Injection, zoledronic acid, 1 mg J3489

Zoledronic acid is a medication given via injection to strengthen bones. It's often used in patients with osteoporosis or certain types of cancer. The injection helps reduce the risk of fractures and other bone complications.

357 services34 patients

Infusion into a vein for therapy, prevention, or diagnosis, 1 hour or less 96365

This is a procedure where a medical professional inserts a small tube into your vein to deliver medication, nutrients, or fluids directly into your bloodstream. This can be for treatment, prevention, or diagnosis. The process typically takes less than an hour.

347 services167 patients

Injection, carboplatin, 50 mg J9045

Carboplatin is a chemotherapy drug used to treat various types of cancer by slowing or stopping the growth of cancer cells. The 50 mg injection is administered into a vein by a healthcare professional. Side effects may occur.

308 services21 patients

Injection, leucovorin calcium, per 50 mg J0640

Leucovorin calcium is an injection given to enhance the effectiveness of certain cancer treatments or to reduce the harmful effects of some medications. The dose is determined by your doctor and is typically administered in a healthcare setting.

197 services11 patients

Administration of non-hormonal anti-neoplastic chemotherapy under skin or into muscle 96401

This procedure involves giving anti-cancer drugs, which don't contain hormones, into the muscle or under the skin. These drugs help to stop the growth of cancer cells. The process is usually quick and done by a healthcare professional.

184 services37 patients

Administration of chemotherapy into vein, each additional hour 96415

Chemotherapy is a treatment method that uses drugs to destroy cancer cells. The drugs are administered into a vein, usually in the arm. Each additional hour of chemotherapy allows for more of the medication to enter your bloodstream to fight against the cancer cells.

173 services44 patients

Injection, fluorouracil, 500 mg J9190

Fluorouracil is a chemotherapy drug, given as an injection to treat various types of cancer. The 500 mg dose helps to stop cancer cells from growing and multiplying. You might feel some side effects, but these are typically manageable.

169 services13 patients

Injection, diphenhydramine hcl, up to 50 mg J1200

Diphenhydramine HCL injection is a medicine given to alleviate symptoms of allergies, colds, or hay fever. It can also help with motion sickness and certain symptoms of Parkinson's disease. Up to 50 mg may be administered depending on your condition.

166 services60 patients

Administration of additional new drug or substance into vein, 1 hour or less 96417

This procedure involves introducing a new drug or substance into your vein, typically via an IV drip. It lasts for an hour or less. This method allows the substance to quickly reach your bloodstream, ensuring rapid and effective treatment.

149 services41 patients

Infusion into a vein for therapy, prevention, or diagnosis, additional sequential infusion, 1 hour or less 96367

This procedure involves injecting fluids or medication directly into your vein. It's used for treatment, prevention, or diagnosis. An additional sequential infusion may be given within an hour if needed. This helps to ensure the medicine is distributed effectively in your body.

116 services48 patients

Infusion into a vein for therapy, prevention, or diagnosis, each additional hour 96366

This procedure involves delivering medication, fluids, or nutrients directly into your vein. This is done to treat, prevent, or diagnose various conditions. Each additional hour refers to the extended time you may need to receive these substances for optimal results.

115 services30 patients

Injection of drug or substance into vein 96374

This procedure involves introducing a medication or substance directly into your vein using a syringe. It's a quick and efficient way to deliver treatment throughout your body. You might feel a small prick when the needle enters. It's generally safe and effective.

114 services71 patients

Infusion, normal saline solution , 1000 cc J7030

An infusion of normal saline solution, 1000 cc, is a common medical procedure. It involves introducing a saltwater solution into your bloodstream via an intravenous (IV) line. This helps to hydrate your body, correct electrolyte imbalances, and deliver medications if needed.

99 services59 patients

Infusion into a vein for hydration, each additional hour 96361

This procedure involves delivering fluids directly into your vein to keep your body hydrated. It is typically done when oral hydration is insufficient. Each additional hour means more fluid is infused to ensure adequate hydration.

86 services37 patients

New patient office or other outpatient visit with low level of medical decision making, if using time, 30 minutes or more 99203

This service involves an initial office or outpatient visit for a new patient. The healthcare professional will spend 30-44 minutes understanding your health history, current issues, and discussing possible treatment plans. It's a comprehensive evaluation to start your healthcare journey.

75 services75 patients

Infusion into a vein for hydration, 31-60 minutes 96360

This is a procedure where a sterile solution is administered into your vein to help restore body fluid balance. It typically lasts between 31-60 minutes. It's a safe, common treatment for dehydration or to deliver medication.

66 services48 patients

New patient office or other outpatient visit with moderate level of medical decision making, if using time, 45 minutes or more 99204

This is a first-time office or outpatient visit lasting between 45-59 minutes. The healthcare provider evaluates your health, discusses your medical history, and may suggest further tests or treatments. It's an opportunity to ask questions and understand your health better.

66 services66 patients

Administration of hormonal anti-neoplastic chemotherapy under skin or into muscle 96402

This procedure involves the injection of hormone-based anti-cancer drugs under the skin or into a muscle. These medications help to slow down or stop the growth of certain types of cancer cells. The process is usually quick and can be performed in a clinic or hospital.

61 services26 patients

Leuprolide acetate (for depot suspension), 7.5 mg J9217

Leuprolide acetate is a medication that helps regulate certain hormone levels in your body. It's injected into your muscle once a month. This treatment can help manage various health conditions related to hormone imbalance. Always follow your doctor's instructions.

60 services12 patients

Drawing of blood for a medical problem 99195

Drawing blood is a simple procedure where a needle is inserted into a vein, usually in your arm, to collect a small sample. This sample helps in diagnosing any medical issues you may have. You might feel a small prick, but overall, it's a quick and safe process.

55 services18 patients

Automated urinalysis test 81003

An automated urinalysis test is a routine examination that checks your urine for various substances. It can help identify potential health issues such as kidney problems or diabetes. The test uses a machine to analyze a small urine sample, providing quick and accurate results.

47 services19 patients

Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes 99232

Follow-up hospital inpatient care involves daily check-ups while you're admitted in the hospital. Typically, a healthcare provider spends about 25 minutes each day reviewing your condition, adjusting treatment if needed, and answering any questions you might have.

41 services27 patients

Infusion, normal saline solution, sterile (500 ml = 1 unit) J7040

An infusion of a normal saline solution is a common medical procedure. Sterile saline (salt water) is administered into your bloodstream via a drip. This helps to maintain fluid balance in your body, especially when you're unable to drink enough liquids.

36 services21 patients

Injection, methylprednisolone sodium succinate, up to 40 mg J2920

Methylprednisolone sodium succinate is a corticosteroid medication, administered via injection. It helps reduce inflammation and immune responses. It's often used to treat conditions like arthritis, allergies, or skin diseases. The dosage is up to 40 mg.

28 services17 patients

Biopsy and aspiration of bone marrow sample for diagnosis 38222

A bone marrow biopsy and aspiration is a procedure where a small amount of bone marrow is removed for testing. It involves inserting a needle into a bone, typically the hip, to collect a sample. It can help diagnose various diseases and monitor treatment effectiveness.

24 services23 patients

Administration of additional new drug or substance into vein using push technique 96411

This procedure involves injecting a new medication or substance directly into your vein using a method called the 'push' technique. It's a quick way to deliver medication into your bloodstream for fast-acting relief or treatment.

24 services15 patients

Office or other outpatient visit for the evaluation and management of established patient that may not require presence of healthcare professional 99211

This service involves an outpatient visit for established patients who may not need direct interaction with a healthcare professional. It could include reviewing test results, monitoring existing conditions, or adjusting treatment plans. It's typically done remotely, ensuring your comfort and convenience.

23 services23 patients

Initial hospital care with straightforward or low-level medical decision making, if using time, at least 55 minutes 99222

Initial hospital inpatient care is a service where a healthcare provider spends about 50 minutes per day overseeing your care while you're admitted in the hospital. This includes reviewing your health status, planning your treatment, and ensuring your safety and comfort.

22 services22 patients

Initial hospital care with moderate level of medical decision making, if using time, at least 75 minutes 99223

Initial hospital inpatient care per day, typically 70 minutes, refers to the daily medical service provided to patients admitted to the hospital. This includes a comprehensive evaluation, diagnosis, treatment plan, and monitoring of your health condition. It ensures your well-being during your hospital stay.

22 services21 patients

Chemotherapy administration, intravenous infusion technique; initiation of infusion in the office/clinic setting using office/clinic pump/supplies, with continuation of the infusion in the community setting (e.g., home, domiciliary, rest home or assisted l G0498

Chemotherapy is a treatment method that uses drugs to destroy cancer cells. In the office, a pump is used to start an intravenous infusion of these drugs. The infusion can then be continued at home or another setting, like a rest home.

22 services11 patients

Transitional care management services for problem of high complexity 99496

Transitional care management services are designed to ensure a smooth transition from a hospital to home or another care setting for patients with complex health issues. These services include medication management, patient education, and coordination with healthcare providers.

17 services16 patients

Infusion into a vein for therapy, prevention, or diagnosis concurrent with another infusion 96368

An infusion into a vein is a method of delivering medication, nutrients, or fluids directly into your bloodstream. If it's concurrent with another infusion, it means two different solutions are given at the same time. This can be for treatment, prevention, or diagnostic purposes.

16 services13 patients

New patient office or other outpatient visit with a high level of medical decision making, if using time, 60 minutes or more 99205

This is a first-time patient visit where a healthcare professional spends 60-74 minutes with you. It involves a comprehensive evaluation, including your medical history and current health condition. They'll also advise on preventive health measures and formulate a treatment plan if needed.

12 services12 patients

Transitional care management services for problem of at least moderate complexity 99495

Transitional care management services focus on coordinating and managing your care after you leave the hospital. For moderate complexity problems, this involves managing your medications, arranging further treatments, and ensuring you have the necessary follow-ups.

11 services11 patients

Hospital Affiliations CMS Care Compare 3

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Lee Memorial Hospital

Acute Care Hospitals · Fort Myers, FL

5/5 CMS rating

OwnershipGovernment - Hospital District or Authority

CMS Certification Number100012

Location2776 Cleveland AveFort Myers, FL 33901 · Lee County

Emergency services Birthing friendly

Gulf Coast Medical Center Lee Health

Acute Care Hospitals · Fort Myers, FL

4/5 CMS rating

OwnershipGovernment - Hospital District or Authority

CMS Certification Number100220

Location13681 Doctors WayFort Myers, FL 33912 · Lee County

Emergency services

Cape Coral Hospital

Acute Care Hospitals · Cape Coral, FL

4/5 CMS rating

OwnershipGovernment - Hospital District or Authority

CMS Certification Number100244

Location636 Del Prado BlvdCape Coral, FL 33990 · Lee County

Emergency services Birthing friendly

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 33908 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient

$179.05 typical visit price

range $58.56 – $179.05

Typical copayment $44.76 (range $14.64 – $44.76)

Most-billed visit code 99205

Established Patient

$103.21 typical visit price

range $18.44 – $144.68

Typical copayment $25.80 (range $4.61 – $36.17)

Most-billed visit code 99214

Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Medicare Quality Performance CMS QPP · MIPS

Performance in the CMS Quality Payment Program: the MIPS final score across four weighted categories, and the individual quality measures reported to Medicare.

75/100

MIPS Final ScoreMerit-based Incentive Payment System · CMS Quality Payment Program

Scored as part of a group practice