MARIANA MUREA MD
Prescription History 1396792321
Internal Medicine - Nephrology in Winston Salem, NC

NPI Status: Active since May 27, 2006

Contact Information

MEDICAL CENTER BLVD
WAKE FOREST UNIVERSITY BAPTIST MEDICAL CENTER
WINSTON SALEM, NC
ZIP 27157
Phone: (336) 716-4650
Fax: (336) 716-4318

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Prescription History for Informed Healthcare Decisions

Explore the verified Medicare Part D prescription history, volume metrics, and calculated drug costs for MARIANA MUREA MD, an active Nephrology specialist practicing in Winston Salem, NC. Our medical registry currently tracks 14 unique pharmaceutical formulations prescribed by this provider, representing an estimated volume of 273 documented patient claims. Among these therapy options, the most frequently utilized medication is Sevelamer Carbonate, which accounts for 54 claims alone.


Alprazolam

Generic Formulation: AlprazolamSpecialty: Nephrology
Provider Metrics Summary
Total Claims 12
30-Day Fills 13.0
Days Supply 390
NC State Average Benchmarks
Peer Average Claims73.0
Peer Average 30-Day Fills79.4
Peer Average Days Supply2,216
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 83.6% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $51.19 across this reporting matrix range.

Provider Avg Cost Per Claim

$4.27

State Avg Cost Per Claim

$9.04

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)

Therapeutic Applications

Alprazolam is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA).

Amitriptyline Hcl

Generic Formulation: Amitriptyline HclSpecialty: Nephrology
Provider Metrics Summary
Total Claims 13
30-Day Fills 13.0
Days Supply 364
NC State Average Benchmarks
Peer Average Claims28.0
Peer Average 30-Day Fills50.0
Peer Average Days Supply1,485
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 53.6% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $85.64 across this reporting matrix range.

Provider Avg Cost Per Claim

$6.59

State Avg Cost Per Claim

$22.34

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

This medication is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, help you sleep better, and increase your energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters such as serotonin) in the brain.

Amlodipine Besylate

Generic Formulation: Amlodipine BesylateSpecialty: Nephrology
Provider Metrics Summary
Total Claims 22
30-Day Fills 66.0
Days Supply 1,980
NC State Average Benchmarks
Peer Average Claims146.0
Peer Average 30-Day Fills342.9
Peer Average Days Supply10,189
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 84.9% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $221.47 across this reporting matrix range.

Provider Avg Cost Per Claim

$10.07

State Avg Cost Per Claim

$7.33

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.

Therapeutic Applications

Amlodipine is used with or without other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Amlodipine belongs to a class of drugs known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily. Amlodipine is also used to prevent certain types of chest pain (angina). It may help to increase your ability to exercise and decrease the frequency of angina attacks. It should not be used to treat attacks of chest pain when they occur. Use other medications (such as sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor.

Bumetanide

Generic Formulation: BumetanideSpecialty: Nephrology
Provider Metrics Summary
Total Claims 18
30-Day Fills 27.0
Days Supply 781
NC State Average Benchmarks
Peer Average Claims29.0
Peer Average 30-Day Fills46.9
Peer Average Days Supply1,337
Conservative Utilization

This provider writes prescriptions for this formulation 37.9% less frequently than the standard regional baseline metric for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $585.30 across this reporting matrix range.

Provider Avg Cost Per Claim

$32.52

State Avg Cost Per Claim

$56.41

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A sulfamyl diuretic.

Therapeutic Applications

Bumetanide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. Bumetanide is a water pill (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt.

Calcium Acetate

Generic Formulation: Calcium AcetateSpecialty: Nephrology
Provider Metrics Summary
Total Claims 28
30-Day Fills 32.0
Days Supply 960
NC State Average Benchmarks
Peer Average Claims30.0
Peer Average 30-Day Fills44.3
Peer Average Days Supply1,273
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $2,669.53 across this reporting matrix range.

Provider Avg Cost Per Claim

$95.34

State Avg Cost Per Claim

$112.18

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Calcium acetate is used to prevent high blood phosphate levels in patients who are on dialysis due to severe kidney disease. Dialysis removes some phosphate from your blood, but it is difficult to remove enough to keep your phosphate levels balanced. Decreasing blood phosphate levels can help keep your bones strong, prevent unsafe buildup of minerals in your body, and possibly decrease the risk of heart disease and strokes that can result from high phosphate levels. Calcium acetate is a natural mineral that works by holding onto phosphate from the diet so that it can pass out of your body.

Carvedilol

Generic Formulation: CarvedilolSpecialty: Nephrology
Provider Metrics Summary
Total Claims 15
30-Day Fills 45.0
Days Supply 1,350
NC State Average Benchmarks
Peer Average Claims64.0
Peer Average 30-Day Fills140.2
Peer Average Days Supply4,144
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 76.6% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $212.76 across this reporting matrix range.

Provider Avg Cost Per Claim

$14.18

State Avg Cost Per Claim

$11.30

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A carbazole and propanol derivative that acts as a non-cardioselective beta blocker and vasodilator. It has blocking activity for ALPHA 1 ADRENERGIC RECEPTORS and, at higher doses, may function as a blocker of CALCIUM CHANNELS; it also has antioxidant properties. Carvedilol is used in the treatment of HYPERTENSION; ANGINA PECTORIS; and HEART FAILURE. It can also reduce the risk of death following MYOCARDIAL INFARCTION.

Therapeutic Applications

Carvedilol is used to treat high blood pressure and heart failure. It is also used after a heart attack to improve the chance of survival if your heart is not pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers your heart rate, blood pressure, and strain on your heart. Carvedilol belongs to a class of drugs known as alpha and beta blockers.

Clinisol

Generic Formulation: Parenteral Amino Acid 15% No.5Specialty: Nephrology
Provider Metrics Summary
Total Claims 21
30-Day Fills 21.0
Days Supply 141
NC State Average Benchmarks
Peer Average Claims46.0
Peer Average 30-Day Fills46.6
Peer Average Days Supply323
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 54.3% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $2,651.95 across this reporting matrix range.

Provider Avg Cost Per Claim

$126.28

State Avg Cost Per Claim

$141.33

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Furosemide

Generic Formulation: FurosemideSpecialty: Nephrology
Provider Metrics Summary
Total Claims 15
30-Day Fills 30.7
Days Supply 920
NC State Average Benchmarks
Peer Average Claims84.0
Peer Average 30-Day Fills161.5
Peer Average Days Supply4,660
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 82.1% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $196.63 across this reporting matrix range.

Provider Avg Cost Per Claim

$13.11

State Avg Cost Per Claim

$6.11

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.

Therapeutic Applications

Furosemide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Furosemide is a water pill (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt.

Hydralazine Hcl

Generic Formulation: Hydralazine HclSpecialty: Nephrology
Provider Metrics Summary
Total Claims 13
30-Day Fills 28.0
Days Supply 837
NC State Average Benchmarks
Peer Average Claims40.0
Peer Average 30-Day Fills76.3
Peer Average Days Supply2,225
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 67.5% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $300.27 across this reporting matrix range.

Provider Avg Cost Per Claim

$23.10

State Avg Cost Per Claim

$20.92

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Hydralazine is used with or without other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydralazine is called a vasodilator. It works by relaxing blood vessels so blood can flow through the body more easily.

Isosorbide Mononitrate Er

Generic Formulation: Isosorbide MononitrateSpecialty: Nephrology
Provider Metrics Summary
Total Claims 13
30-Day Fills 21.0
Days Supply 630
NC State Average Benchmarks
Peer Average Claims46.0
Peer Average 30-Day Fills97.0
Peer Average Days Supply2,866
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 71.7% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $173.25 across this reporting matrix range.

Provider Avg Cost Per Claim

$13.33

State Avg Cost Per Claim

$18.44

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). This medication belongs to a class of drugs known as nitrates. It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medication will not relieve chest pain once it occurs. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Other medications may be prescribed by your doctor for these conditions. Consult your doctor for more details.

Losartan Potassium

Generic Formulation: Losartan PotassiumSpecialty: Nephrology
Provider Metrics Summary
Total Claims 12
30-Day Fills 32.0
Days Supply 960
NC State Average Benchmarks
Peer Average Claims102.0
Peer Average 30-Day Fills249.3
Peer Average Days Supply7,435
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 88.2% less volume than the regional standard for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $133.29 across this reporting matrix range.

Provider Avg Cost Per Claim

$11.11

State Avg Cost Per Claim

$10.52

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.

Therapeutic Applications

Losartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Losartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily.

Midodrine Hcl

Generic Formulation: Midodrine HclSpecialty: Nephrology
Provider Metrics Summary
Total Claims 12
30-Day Fills 20.0
Days Supply 578
NC State Average Benchmarks
Peer Average Claims24.0
Peer Average 30-Day Fills31.7
Peer Average Days Supply851
Conservative Utilization

This provider writes prescriptions for this formulation 50.0% less frequently than the standard regional baseline metric for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $569.72 across this reporting matrix range.

Provider Avg Cost Per Claim

$47.48

State Avg Cost Per Claim

$82.85

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

This medication is used for certain patients who have symptoms of low blood pressure when standing. This condition is also known as orthostatic hypotension. Midodrine is used in people whose daily activities are severely affected by this condition, even after other treatments are used (such as support stockings). It is known as a sympathomimetic (alpha receptor agonist) that acts on the blood vessels to raise blood pressure.

Prosol

Generic Formulation: Parenteral Amino Acid 20% No.1Specialty: Nephrology
Provider Metrics Summary
Total Claims 25
30-Day Fills 25.0
Days Supply 160
NC State Average Benchmarks
Peer Average Claims41.0
Peer Average 30-Day Fills41.3
Peer Average Days Supply285
Conservative Utilization

This provider writes prescriptions for this formulation 39.0% less frequently than the standard regional baseline metric for practitioners inside NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $4,037.13 across this reporting matrix range.

Provider Avg Cost Per Claim

$161.49

State Avg Cost Per Claim

$163.83

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.

Sevelamer Carbonate

Generic Formulation: Sevelamer CarbonateSpecialty: Nephrology
Provider Metrics Summary
Total Claims 54
30-Day Fills 84.0
Days Supply 2,509
NC State Average Benchmarks
Peer Average Claims43.0
Peer Average 30-Day Fills62.9
Peer Average Days Supply1,798
Elevated Utilization

This provider maintains an active emphasis on this therapeutic option, recording 25.6% more claims than the standard regional baseline profile for NC. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $14,009.19 across this reporting matrix range.

Provider Avg Cost Per Claim

$259.43

State Avg Cost Per Claim

$315.20

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A polymeric amine that binds phosphate and is used to treat HYPERPHOSPHATEMIA in patients with kidney disease.

Therapeutic Applications

Sevelamer is used to lower high blood phosphorus (phosphate) levels in patients who are on dialysis due to severe kidney disease. Dialysis removes some phosphate from your blood, but it is difficult to remove enough to keep your phosphate levels balanced. Decreasing blood phosphate levels can help keep your bones strong, prevent unsafe buildup of minerals in your body, and possibly decrease the risk of heart disease and strokes that can result from high phosphate levels. Sevelamer works by holding onto phosphate from the diet so that it can pass out of your body.

Dataset Methodology & CMS Source Information

This analytical profile maps public infrastructure records sourced directly from official **Centers for Medicare & Medicaid Services (CMS)** public data releases. The statistics above track documented pharmaceutical treatment trends assigned to beneficiaries specifically under federal public programs. Evaluating the prescriptive footprints of clinical practitioners like MARIANA MUREA MD provides transparency into local medical care patterns within Winston Salem, NC.

Key Learning Objectives for this Profile:

  • Prescribing Frequencies: Track and evaluate the volume metrics of specific brand-name and generic medical formulas chosen by this provider over time.
  • Clinical Focus Areas: Identify how the provider distributes therapeutic selections across medical care options to gain insight into their true day-to-day **Nephrology** practice concentrations.
  • Program Cost Awareness: Review the calculated total systemic drug costs and raw transactional volumes linked to these orders to better anticipate network insurance coverage structures.
  • Patient-Centered Evaluation: Cross-reference localized regional care comparisons to align practitioner habits directly with your proactive health maintenance goals.

Data Scope Exclusion & Limitations: The data elements presented above explicitly reflect prescription orders processed for Medicare beneficiaries during the year 2023. This informational profile does not aggregate prescription data for individuals utilizing private commercial health plans, state Medicaid coverage, or self-pay options. However, because medical decision-making remains highly consistent across clinical settings, this public registry provides a reliable proxy for understanding the general prescribing preferences and pharmaceutical care approach used by this provider.