PRINCIPLE LABS LLC
NPI 1346648870
Clinical Medical Laboratory in Bethlehem, PA

Q: What is Principle Labs LLC's NPI number?

The NPI number for Principle Labs LLC is 1346648870. It was assigned to this organization in the NPPES registry on December 16, 2014.

Q: What is Principle Labs LLC's specialty?

The primary specialty registered for this NPI is Clinical Medical Laboratory with taxonomy code 291U00000X.

Active since December 16, 2014CLIA Certified · 2 labs

2550 BRODHEAD RD, SUITE 105, BETHLEHEM, PA 18020(484) 353-6661(484) 353-6663 Get Directions Write a Review

NPPES record last updated: December 16, 2014. Verified against the NPPES registry weekly; last sync: August 16, 2026.

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About Principle Labs Llc NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

PRINCIPLE LABS LLC (NPI 1346648870) is a healthcare organization registered as a clinical medical laboratory in Bethlehem, Pennsylvania and active in the NPI registry since December 2014. The organization holds 2 active CLIA laboratory certificates and lists Jason Polete, Coo, as its authorized official.

NPPES Registry Identity

NPI1346648870

Entity TypeOrganization

Primary Taxonomy291U00000X

Legal Business NamePRINCIPLE LABS LLC

Location Address2550 BRODHEAD RD, SUITE 105Bethlehem, PA 18020-8922

Mailing Address2550 Brodhead Rd, Suite 105Bethlehem, PA 18020-8922 · (484) 353-6661 · Fax (484) 353-6663

Phone(484) 353-6661

Fax(484) 353-6663

Organization SubpartNo

Authorized OfficialJason PoleteCoo · (484) 353-6661

Enumeration DateDecember 16, 2014

✔ NPI 1346648870 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyClinical Medical LaboratoryLaboratories

Taxonomy Code291U00000X

Definition

(1) A clinical laboratory is a facility for the biological, microbiological, serological, chemical, immunohematological, hematological, biophysical, cytological, pathological, or other examination of materials derived from the human body for the purpose of providing information for the diagnosis, prevention, or treatment of any disease or impairment of, human beings. These examinations also include procedures to determine, measure, or otherwise describe the presence or absence of various substances or organisms in the body. Facilities only collecting or preparing specimens (or both) or only serving as a mailing service and not performing testing are not considered clinical laboratories. (2) Any facility that examines materials from the human body for purposes of providing information for the diagnosis, prevention, or treatment of any disease or impairment of, or the assessment of, the health of human beings. Typical divisions of a clinical laboratory include hematology, cytology, bacteriology, histology, biochemistry, medical toxicology, and serology.

2550 BRODHEAD RD, Bethlehem, PA 18020

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Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Ambetter from Arkansas Health & Wellness, Ambetter from Buckeye Health Plan, Ambetter from Home State Health and more.Insurance ›

CLIA Laboratory Certificates CMS CLIA 2

Laboratory certificates issued under the Clinical Laboratory Improvement Amendments (CLIA) program, which sets federal quality standards for human laboratory testing in the United States. There is no official CMS crosswalk between CLIA and NPI numbers; these certificates are associated with this NPI by matching facility names, locations and phone numbers in the CMS CLIA registry.

Certificate of Accreditation 39D2087560

Principle Labs, LLC · Bethlehem, PA

Active · expires Jun 28, 2028

CLIA Number39D2087560

Laboratory TypeIndependent

Certificate Effective DateJune 29, 2026

Certificate Expiration DateJune 28, 2028

Laboratory DirectorDr. Xuehui Liu

Laboratory Phone(484) 353-6661

Laboratory LocationPrinciple Labs, LLC2550 Brodhead Road, Suite 105, Bethlehem, PA 18020

CLIA data matches this NPI record on: Address Name Phone

This is a certificate that is issued to a laboratory on the basis of the laboratory's accreditation by an accreditation organization approved by CMS.

Certificate of Waiver 21D2162856

Principle Diagnostic Laboratory · Havre De Grace, MD

Active · expires Mar 3, 2027

CLIA Number21D2162856

Laboratory TypePhysician Office

Certificate Effective DateMarch 4, 2025

Certificate Expiration DateMarch 3, 2027

Laboratory DirectorYaroslav Krymskiy

Laboratory Phone(484) 353-6661

Laboratory LocationPrinciple Diagnostic Laboratory253 Lewis Lane Suite 302, Havre De Grace, MD 21078

CLIA data matches this NPI record on: Phone

This certificate is issued to a laboratory to perform only waived tests.

Areas of Expertise CMS Part B claims 55

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Detection test by nucleic acid for organism, amplified probe technique 87798

A nucleic acid detection test is a procedure to identify specific organisms in your body. This test uses an amplified probe technique, which magnifies the genetic material of the organism, making it easier to detect. It's a precise way to diagnose infections.

70,784 services3,218 patients

Detection test for candida species (yeast), amplified probe technique 87481

This test helps identify Candida, a type of fungus often present in the human body. An amplified probe technique is used, which enhances detection of the fungus in a sample. This method increases the accuracy of the test, helping to determine the best treatment.

23,801 services3,095 patients

Detection of mycoplasma genitalium by dna or rna probe 87563

This procedure involves the use of special probes to identify the presence of a specific bacteria, Mycoplasma Genitalium, in your body. These probes detect the bacteria's unique DNA or RNA, helping to confirm if you have an infection.

5,500 services3,033 patients

Amplifed dna or rna probe detection of severe acute respiratory syndrome coronavirus 2 (covid-19) antigen 87635

This is a lab test that detects the presence of COVID-19 in your body. It uses a technique to amplify the virus's genetic material, either DNA or RNA, making it easier to identify. A positive result indicates an active infection.

5,475 services507 patients

Detection test by nucleic acid for staphylococcus aureus (bacteria), amplified probe technique 87640

A detection test for Staphylococcus aureus uses a method called the amplified probe technique. This method identifies the bacteria's unique genetic material, or nucleic acid, helping to confirm its presence. It's a highly accurate way to detect this type of bacteria.

5,347 services3,138 patients

Detection test by nucleic acid for strep (streptococcus, group b), amplified probe technique 87653

A detection test by nucleic acid for Group B Strep uses an amplified probe technique. This test identifies the presence of Group B Strep bacteria in the body. It involves collecting a sample, usually a swab, which is then examined in a lab for the bacteria's genetic material.

5,332 services3,092 patients

Detection test by nucleic acid for vancomycin resistance strep (vre), amplified probe technique 87500

The detection test by nucleic acid for vancomycin-resistant strep (VRE) is a laboratory procedure. It uses an amplified probe technique to identify specific genetic material in bacteria. This helps determine if the bacteria are resistant to the antibiotic vancomycin.

5,035 services3,028 patients

Detection test by nucleic acid for staphylococcus aureus, methicillin resistant (mrsa bacteria), amplified probe technique 87641

A detection test by nucleic acid for MRSA bacteria uses an amplified probe technique. It's a lab procedure that identifies the presence of MRSA, a type of bacteria resistant to many antibiotics. This test helps in deciding the best treatment.

4,872 services2,943 patients

Detection test by nucleic acid for strep (streptococcus, group a), amplified probe technique 87651

This test detects Group A Streptococcus bacteria in your body. It uses an amplified probe technique, which amplifies the bacteria's nucleic acid, making it easier to identify. This test helps diagnose conditions like strep throat or scarlet fever.

3,869 services2,437 patients

Testing for presence of drug, by chemistry analyzers 80307

Chemistry analyzers are used to detect the presence of drugs in your system. This test involves taking a small sample of your blood or urine. The sample is then analyzed for specific substances. The results help in understanding your health condition better.

2,649 services382 patients

Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms G0482

A definitive drug test identifies specific drugs in your system. Advanced methods like GC/MS (Gas Chromatography/Mass Spectrometry) and LC/MS (Liquid Chromatography/Mass Spectrometry) are used. These can distinguish between similar drugs, providing precise results.

2,118 services659 patients

Detection test by nucleic acid for herpes simplex virus, amplified probe technique 87529

This test uses an amplified probe technique to identify the presence of the herpes simplex virus in your body. It works by detecting the virus's genetic material, or nucleic acid. The test is accurate, reliable, and can help in early detection and treatment.

1,700 services661 patients

A definitive drug test is a detailed examination that can identify specific drugs in your system, even closely related ones. Techniques like GC/MS and LC/MS are used for high precision. This helps ensure accurate results for your safety and health.

1,558 services192 patients

Detection test by nucleic acid for multiple organisms, amplified probe(s) technique 87801

This is a test that identifies various microorganisms in your body using a method called amplified probe technique. It targets specific genetic material (nucleic acids) of the organisms, amplifying them for easy detection. This helps in diagnosing infections accurately.

1,339 services549 patients

Detection test by nucleic acid for chlamydia trachomatis, amplified probe technique 87491

A detection test by nucleic acid for chlamydia trachomatis, amplified probe technique, is a test that identifies the presence of a specific bacteria in the body. This bacteria can cause various health issues. The technique amplifies the sample to improve accuracy.

1,300 services1,000 patients

Detection test by nucleic acid for multiple types of respiratory virus, multiple types or subtypes, 3-5 targets 87631

This test identifies different respiratory viruses by examining their nucleic acid, the building blocks of their genetic material. It can detect multiple types or subtypes, specifically 3-5 targets. This helps in diagnosing your respiratory illness accurately.

1,266 services486 patients

Detection by nucleic acid bartonella henselae and bartonella quintana (bacteria), amplified probe technique 87471

This is a lab test that identifies Bartonella Henselae and Bartonella Quintana bacteria in your body. The amplified probe technique is used to increase the amount of bacterial DNA, making it easier to detect. This helps in diagnosing diseases caused by these bacteria.

775 services632 patients

Detection test by nucleic acid for mycobacteria avium-intracellulare (bacteria), amplified probe technique 87561

This test identifies the presence of Mycobacteria Avium-Intracellulare, bacteria often linked with lung diseases. The amplified probe technique enhances the detection process by amplifying the bacteria's nucleic acid, making it easier to spot.

698 services555 patients

Detection test by nucleic acid for clostridium difficile, amplified probe technique 87493

A detection test by nucleic acid for Clostridium difficile using an amplified probe technique is a lab test that identifies the presence of the Clostridium difficile bacteria in your body. It uses a small sample, often stool, and a technique that amplifies the bacteria's genetic material to confirm its presence.

653 services526 patients

A definitive drug test is a detailed analysis used to identify specific drugs in your system. It uses advanced techniques, such as gc/ms and lc/ms, to detect and distinguish between different drugs, even those with similar structures.

541 services105 patients

Gene analysis (cytochrome p450, family 2, subfamily d, polypeptide 6) common variants 81226

Gene analysis of cytochrome P450 2D6 (CYP2D6) common variants involves studying specific genes to understand your body's ability to process certain medications. This can help tailor treatments to your unique genetic makeup, optimizing medication effectiveness and safety.

229 services229 patients

Gene analysis (cytochrome p450, family 2, subfamily c, polypeptide 19) common variants 81225

Gene analysis of cytochrome P450 2C19 common variants is a test that helps understand how your body processes certain medications. This can help your doctor tailor treatments specifically for you, improving their effectiveness and safety.

198 services198 patients

Detection test by nucleic acid for human papillomavirus (hpv), types 16 and 18 only 87625

This test identifies specific types of HPV, a common virus, by examining your body's cells for the virus's genetic material. It's specifically designed to detect types 16 and 18, which are often associated with certain health risks. The procedure is safe and simple.

184 services110 patients

Detection test by nucleic acid for trichomonas vaginalis (genital parasite), amplified probe technique 87661

This is a test to identify a common microscopic organism that can cause discomfort. The technique involves using a special probe to amplify the organism's genetic material, making it easier to detect. It's a simple, safe, and accurate procedure.

184 services111 patients

Complete blood cell count (red cells, white blood cell, platelets), automated test and automated differential white blood cell count 85025

A Complete Blood Cell Count is a common test that measures various components of the blood, including red cells (carry oxygen), white cells (fight infection), and platelets (help blood clot). An automated test ensures accuracy. The differential count provides detailed information about white cell types.

117 services104 patients

Blood test, comprehensive group of blood chemicals 80053

A comprehensive group of blood chemicals test, also known as a comprehensive metabolic panel, is a blood test that measures your sugar level, electrolyte and fluid balance, kidney function, and liver function. This helps to check your body's overall health.

104 services97 patients

Detection test for gardnerella vaginalis (bacteria), amplified probe technique 87511

This test helps find a specific type of bacteria in the body. It uses a method called the amplified probe technique, which amplifies the bacteria's genetic material, making it easier to detect. It's a standard, pain-free procedure.

99 services68 patients

Detection test by nucleic acid for digestive tract pathogen, multiple types or subtypes, 6-11 targets 87506

This test identifies various pathogens in the digestive system by examining nucleic acids. It targets 6-11 different types or subtypes of these pathogens, helping to diagnose a range of potential illnesses.

98 services86 patients

Detection test by nucleic acid for neisseria gonorrhoeae (gonorrhoeae bacteria), amplified probe technique 87591

This is a lab test that checks for the presence of a specific bacteria called Neisseria gonorrhoeae in your body. It uses a technique called amplified probe, which makes many copies of the bacteria's genetic material (nucleic acid) to help detect it more easily.

74 services69 patients

Blood test, thyroid stimulating hormone (tsh) 84443

A TSH blood test measures the level of thyroid stimulating hormone in your body. This hormone is produced by the pituitary gland and regulates how your thyroid works. It's a simple procedure where a small amount of blood is drawn from your arm for analysis.

49 services49 patients

Blood test, basic group of blood chemicals (calcium, total) 80048

A basic group blood test measures the levels of certain chemicals in your blood, including calcium. This helps assess your overall health and detect potential problems. The procedure involves drawing a small amount of blood from your arm, which is then analyzed in a lab.

48 services39 patients

Manual urinalysis test with examination using microscope, automated 81001

A manual urinalysis test with automated microscopic examination is a lab process that checks your urine for health indicators. It involves a machine scanning your sample to identify any abnormal elements, which can assist in diagnosing various conditions.

46 services36 patients

Detection test by nucleic acid for mycoplasma pneumoniae (bacteria), amplified probe technique 87581

This test checks for Mycoplasma pneumoniae, a bacteria that can cause lung infection. It uses a method called amplified probe technique, which identifies the bacteria's genetic material. This helps in diagnosing the infection accurately.

39 services37 patients

Blood test, clotting time 85610

A clotting time blood test helps determine how quickly your blood forms clots, a process crucial to stop bleeding. During the test, a small blood sample is taken from your arm. The sample is then analyzed in a lab to see how long it takes for a clot to form.

37 services13 patients

Bacterial culture for aerobic isolates 87077

A bacterial culture for aerobic isolates is a lab test that helps identify bacteria that thrive in oxygen-rich environments. A sample from the suspected infection site is collected, then placed in a special medium that promotes bacterial growth. After a set period, the lab identifies any bacteria present, aiding in accurate diagnosis and treatment.

33 services22 patients

Blood test, lipids (cholesterol and triglycerides) 80061

A lipid panel is a blood test that measures fats and fatty substances, such as cholesterol and triglycerides. These substances are used by your body as a source of energy. High levels can lead to health issues, including heart disease.

32 services31 patients

Detection test by nucleic acid for strep (streptococcus, group a), direct probe technique 87650

This test detects the presence of Group A Streptococcus bacteria, often causing throat infections, using a direct probe technique. It involves taking a throat swab sample, then applying a special probe that binds to the bacteria's nucleic acid, if present.

31 services28 patients

Thyroxine (thyroid chemical), free 84439

The Thyroxine (thyroid chemical), free test is a blood test that measures the level of free T4 in your body. T4 is a hormone produced by your thyroid gland and is essential for growth and metabolism. If your T4 levels are too high or too low, it could indicate a thyroid disorder.

30 services30 patients

Bacterial urine culture 87088

A bacterial urine culture is a laboratory test that checks for bacteria in your urine. It helps identify the type of bacteria causing an infection, enabling the selection of the most effective treatment. The test involves collecting a urine sample in a sterile container.

29 services19 patients

Evaluation of antimicrobial drug (antibiotic, antifungal, antiviral), microdilution or agar dilution 87186

This process checks how well certain drugs, like antibiotics, can fight against infections. It involves mixing the drug with a microbe (like bacteria or a virus) in a lab. By observing how the microbe reacts, it helps determine the best drug to treat your infection.

28 services22 patients

Automated urinalysis test 81003

An automated urinalysis test is a routine examination that checks your urine for various substances. It can help identify potential health issues such as kidney problems or diabetes. The test uses a machine to analyze a small urine sample, providing quick and accurate results.

26 services24 patients

Bacterial colony count, urine 87086

A bacterial colony count, urine, is a laboratory test that checks a urine sample for bacteria. It helps to identify if an infection is present in the urinary system. High numbers of bacteria in the urine can indicate a urinary tract infection (UTI).

24 services21 patients

Natriuretic peptide (heart and blood vessel protein) level 83880

A natriuretic peptide level test is a blood test that helps doctors check for heart failure. It measures the amount of certain proteins that your heart and blood vessels produce when they are under stress. High levels may indicate heart disease.

23 services21 patients

Parathormone (parathyroid hormone) level 83970

The Parathormone level test measures the amount of parathyroid hormone in your blood. This hormone controls calcium and phosphorus levels in the body, which are vital for bone health. Abnormal levels may indicate issues like kidney disease or parathyroid gland disorders.

23 services14 patients

Gene analysis (solute carrier organic anion transporter family, member 1b1) for common variant 81328

Gene analysis for the solute carrier organic anion transporter family, member 1b1 (SLCO1B1), common variant, is a test that examines your DNA to identify variations in the SLCO1B1 gene. This gene plays a crucial role in the body's ability to process certain medications.

21 services21 patients

Valproic acid level, total 80164

A Valproic Acid Level, Total test measures the amount of valproic acid, a medication used to treat seizures and mood disorders, in your blood. This helps ensure the drug is working effectively and safely. Regular testing is necessary to monitor and adjust dosage if needed.

20 services18 patients

Urinalysis, manual test 81002

A urinalysis is a simple, non-invasive test that checks the urine for various elements such as sugar, protein, and signs of infection. It can help detect many common conditions, including kidney disease and diabetes. The manual test involves a lab technician examining a urine sample.

19 services18 patients

Hemoglobin a1c level 83036

Hemoglobin A1c (HbA1c) is a test that measures your average blood sugar level over the past 2-3 months. It's used to monitor how well diabetes is being controlled. High levels may indicate that your diabetes treatment plan needs adjustment.

19 services18 patients

Thyroid hormone, t3 measurement, total 84480

The T3 Total Test measures the amount of thyroid hormone T3 in your blood. This hormone, produced by the thyroid gland, is crucial for body's metabolism and energy production. Abnormal levels may indicate a thyroid disorder.

19 services19 patients

Vitamin d-3 level 82306

A Vitamin D-3 level test measures the amount of Vitamin D-3, a crucial nutrient, in your body. This test helps identify if your levels are too low or too high. Low levels may lead to bone weakness, while high levels could harm your kidneys. It's a simple blood test.

17 services17 patients

Creatinine level to test for kidney function or muscle injury 82570

A creatinine level test measures the amount of creatinine in your blood. This substance is a waste product from normal muscle use. Higher levels can indicate possible kidney dysfunction or muscle injury. This test helps monitor kidney health.

15 services13 patients

Iron level 83540

An iron level test measures the amount of iron in your blood. Iron is crucial for producing hemoglobin, a protein in red blood cells that carries oxygen throughout your body. This test helps identify iron deficiencies or excesses, which can lead to conditions like anemia or hemochromatosis.

15 services13 patients

Thyroid hormone, t3 measurement, free 84481

The T3 measurement, free, is a blood test that checks the level of a hormone called triiodothyronine. This hormone is produced by your thyroid, a small gland in your neck. It plays a key role in regulating your body's metabolism and energy use.

14 services14 patients

Complete blood cell count (red cells, white blood cell, platelets), automated test 85027

A complete blood cell count (CBC) is an automated test that measures different components of the blood, including red cells, white cells, and platelets. It helps assess overall health, detect disorders like anemia or infection, and monitor medical treatments.

14 services13 patients

Lithium level 80178

A lithium level test is a lab procedure that measures the amount of lithium, a medication often used to treat mental health conditions like bipolar disorder, in your blood. This helps ensure the drug is at a safe and effective level for treatment.

12 services12 patients

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Principle Labs LLC's NPI number?

The NPI number for Principle Labs LLC is 1346648870. It was assigned to this organization in the NPPES registry on December 16, 2014.

Where is Principle Labs LLC located?

Principle Labs LLC is located at 2550 Brodhead Rd Suite 105, Bethlehem, PA 18020. The listed phone number is (484) 353-6661.

What is Principle Labs LLC's specialty?

The primary specialty registered for this NPI is Clinical Medical Laboratory with taxonomy code 291U00000X.

Does Principle Labs LLC hold CLIA laboratory certificates?

Yes. 2 active CLIA laboratory certificates are associated with this NPI under the federal Clinical Laboratory Improvement Amendments program. The certificates are listed in the CLIA Laboratory Certificates section above.

What insurance does Principle Labs LLC accept?

Health plans from Ambetter Health, Ambetter from Arkansas Health & Wellness, Ambetter from Buckeye Health Plan, Ambetter from Home State Health and Ambetter from Meridian and 8 other insurers list Principle Labs LLC as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

When was this NPI record last updated?

The NPPES record for Principle Labs LLC was last updated on December 16, 2014. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 11 years ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.