DAVID CHANG ISHIZAWAR M.D.
Prescription History 1326235607
Internal Medicine - Advanced Heart Failure and Transplant Cardiology in Raleigh, NC
Medicare Part D Prescription History
Explore the verified Medicare Part D prescription history, volume metrics, and calculated drug costs for DAVID CHANG ISHIZAWAR M.D., an active Advanced Heart Failure and Transplant Cardiology specialist practicing in Raleigh, NC. Our medical registry currently tracks 32 unique pharmaceutical formulations prescribed by this provider, representing an estimated volume of 2,011 documented patient claims. Among these therapy options, the most frequently utilized medication is Spironolactone, which accounts for 302 claims alone. Use the table below to sort by claims, cost, or utilization compared with the state average; select any medication for its full profile.
| Medication | Prescriptions (2023)Rx (2023) | Avg Cost per FillCost / Fill | Vs. Other NC PrescribersVs. NC Avg |
|---|---|---|---|
| Spironolactone | 302 | $12.15▼ below NC avg | ▲ More than typical |
About Spironolactone: Spironolactone is used to treat high blood pressure and heart failure. Show more ▾ Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat conditions in which the body is making too much of a natural substance (aldosterone). Spironolactone is known as a water pill (potassium-sparing diuretic). A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827) In 2023, this provider wrote 302 Medicare prescriptions for Spironolactone, about 6.9 times the volume of the typical North Carolina prescriber of this medication (44). Medicare paid an average of $12.15 per fill, versus $12.83 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 819.5 30-Day Fills standardized to 30-day supplies 24,509 Days of Medication total across all patients in 2023 | |||
| JardianceEmpagliflozin | 242 | $992.87 | ▲ More than typical |
About Jardiance: Empagliflozin is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Show more ▾ Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Empagliflozin is also used in patients with type 2 diabetes and heart disease to lower the risk of death from heart attack or stroke. Empagliflozin works by increasing the removal of sugar by your kidneys. Empagliflozin is also used to treat heart failure. It may help you live longer and lower your risk of going to the hospital for heart failure. Empagliflozin works by increasing the removal of sodium by your kidneys. In 2023, this provider wrote 242 Medicare prescriptions for Jardiance, about 5.6 times the volume of the typical North Carolina prescriber of this medication (43). Medicare paid an average of $992.87 per fill, versus $988.36 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 390.1 30-Day Fills standardized to 30-day supplies 11,633 Days of Medication total across all patients in 2023 | |||
| Furosemide | 158 | $8.57 | ▲ More than typical |
About Furosemide: Furosemide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. Show more ▾ This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Furosemide is a water pill (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt. A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY. In 2023, this provider wrote 158 Medicare prescriptions for Furosemide, about 1.9 times the volume of the typical North Carolina prescriber of this medication (84). Medicare paid an average of $8.57 per fill, versus $6.11 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 380.3 30-Day Fills standardized to 30-day supplies 11,361 Days of Medication total across all patients in 2023 | |||
| Ambrisentan | 145 | $5,070.20 | ▲ More than typical |
About Ambrisentan: Ambrisentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension). Show more ▾ This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the effects of endothelin-1, thereby helping to decrease the blood pressure in the lungs, slow the worsening of symptoms, and improve your ability to exercise. In 2023, this provider wrote 145 Medicare prescriptions for Ambrisentan, about 3 times the volume of the typical North Carolina prescriber of this medication (49). Medicare paid an average of $5,070.20 per fill, versus $4,360.60 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 145 30-Day Fills standardized to 30-day supplies 4,350 Days of Medication total across all patients in 2023 | |||
| FarxigaDapagliflozin Propanediol | 117 | $991.92 | ▲ More than typical |
About Farxiga: Dapagliflozin is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Show more ▾ Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. This medication is also used in people with type 2 diabetes and heart disease to lower the risk of going to the hospital for heart failure. Dapagliflozin works by increasing the removal of sugar by your kidneys. Dapagliflozin is also used to treat kidney disease and heart failure. It may help you live longer and lower your risk of going to the hospital for heart failure. Dapagliflozin works by increasing the removal of sodium by your kidneys. In 2023, this provider wrote 117 Medicare prescriptions for Farxiga, about 3.4 times the volume of the typical North Carolina prescriber of this medication (34). Medicare paid an average of $991.92 per fill, versus $917.32 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 203 30-Day Fills standardized to 30-day supplies 5,957 Days of Medication total across all patients in 2023 | |||
| UptraviSelexipag | 113 | $21,397.08▼ below NC avg | ▲ More than typical |
About Uptravi: Selexipag is used to treat high blood pressure in the lungs (pulmonary arterial hypertension-PAH). Show more ▾ It is used to help slow down worsening of PAH and to decrease the chance of needing treatment in a hospital. Selexipag works by making it easier for blood to flow through the arteries in your lungs. This effect helps increase your ability to exercise. In 2023, this provider wrote 113 Medicare prescriptions for Uptravi, about 2.3 times the volume of the typical North Carolina prescriber of this medication (50). Medicare paid an average of $21,397.08 per fill, versus $21,628.96 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 113 30-Day Fills standardized to 30-day supplies 3,280 Days of Medication total across all patients in 2023 | |||
| Metoprolol Succinate | 98 | $31.33 | ≈ Typical |
About Metoprolol Succinate: This medication is a beta-blocker used to treat chest pain (angina), heart failure, and high blood pressure. Show more ▾ Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the action of certain natural chemicals in your body (such as epinephrine) that affect the heart and blood vessels. This lowers heart rate, blood pressure, and strain on the heart. A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS. In 2023, this provider wrote 98 Medicare prescriptions for Metoprolol Succinate, about the same volume as the typical North Carolina prescriber of this medication (103). Medicare paid an average of $31.33 per fill, versus $17.79 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 260.7 30-Day Fills standardized to 30-day supplies 7,814 Days of Medication total across all patients in 2023 | |||
| Sildenafil Citrate | 93 | $829.68 | ▲ More than typical |
About Sildenafil Citrate: Sildenafil is used to treat high blood pressure in the lungs (pulmonary hypertension). Show more ▾ It works by relaxing and widening the blood vessels in your lungs which allows the blood to flow more easily. Decreasing high blood pressure in the lungs allows your heart and lungs to work better and improves your ability to exercise. This medication is not recommended for use in children. Discuss the risks and benefits of this medication with the doctor. A PHOSPHODIESTERASE TYPE-5 INHIBITOR; VASODILATOR AGENT and UROLOGICAL AGENT that is used in the treatment of ERECTILE DYSFUNCTION and PRIMARY PULMONARY HYPERTENSION. In 2023, this provider wrote 93 Medicare prescriptions for Sildenafil Citrate, about 4.7 times the volume of the typical North Carolina prescriber of this medication (20). Medicare paid an average of $829.68 per fill, versus $130.32 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 247 30-Day Fills standardized to 30-day supplies 7,410 Days of Medication total across all patients in 2023 | |||
| AdempasRiociguat | 76 | $13,319.87 | ▲ More than typical |
About Adempas: Riociguat is used to treat high blood pressure in the lungs (pulmonary hypertension). Show more ▾ It can also be used to treat a certain type of high blood pressure in the lungs caused by blood clots (chronic thromboembolic pulmonary hypertension) when surgery has not been fully successful or is impossible. Riociguat works by relaxing and widening the blood vessels in your lungs so blood can flow more easily. Decreasing high blood pressure in the lungs allows your heart and lungs to work better and improves your ability to exercise. In 2023, this provider wrote 76 Medicare prescriptions for Adempas, about 2.2 times the volume of the typical North Carolina prescriber of this medication (35). Medicare paid an average of $13,319.87 per fill, versus $12,671.74 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 76 30-Day Fills standardized to 30-day supplies 2,216 Days of Medication total across all patients in 2023 | |||
| OpsumitMacitentan | 66 | $12,404.34 | ≈ Typical |
About Opsumit: Macitentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension). Show more ▾ This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the effects of endothelin-1, which helps decrease the blood pressure in the lungs, and reduces the risk of worsening of symptoms and hospital stays due to the disease. In 2023, this provider wrote 66 Medicare prescriptions for Opsumit, about 1.2 times the volume of the typical North Carolina prescriber of this medication (55). Medicare paid an average of $12,404.34 per fill, versus $12,083.79 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 66 30-Day Fills standardized to 30-day supplies 1,957 Days of Medication total across all patients in 2023 | |||
| Carvedilol | 65 | $11.03▼ below NC avg | ≈ Typical |
About Carvedilol: Carvedilol is used to treat high blood pressure and heart failure. Show more ▾ It is also used after a heart attack to improve the chance of survival if your heart is not pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers your heart rate, blood pressure, and strain on your heart. Carvedilol belongs to a class of drugs known as alpha and beta blockers. A carbazole and propanol derivative that acts as a non-cardioselective beta blocker and vasodilator. It has blocking activity for ALPHA 1 ADRENERGIC RECEPTORS and, at higher doses, may function as a blocker of CALCIUM CHANNELS; it also has antioxidant properties. Carvedilol is used in the treatment of HYPERTENSION; ANGINA PECTORIS; and HEART FAILURE. It can also reduce the risk of death following MYOCARDIAL INFARCTION. In 2023, this provider wrote 65 Medicare prescriptions for Carvedilol, about the same volume as the typical North Carolina prescriber of this medication (64). Medicare paid an average of $11.03 per fill, versus $11.30 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 163.3 30-Day Fills standardized to 30-day supplies 4,870 Days of Medication total across all patients in 2023 | |||
| EntrestoSacubitril/Valsartan | 63 | $1,306.64 | ≈ Typical |
About Entresto: This product is used to treat certain types of heart failure. Show more ▾ It may help you live longer and lower your chance of having to go to the hospital for heart failure. This product contains 2 medications: sacubitril and valsartan. Sacubitril belongs to a class of drugs called neprilysin inhibitors and valsartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). They work by relaxing blood vessels so that blood can flow more easily, which makes it easier for your heart to pump blood to your body. In 2023, this provider wrote 63 Medicare prescriptions for Entresto, about 1.2 times the volume of the typical North Carolina prescriber of this medication (52). Medicare paid an average of $1,306.64 per fill, versus $935.96 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 137 30-Day Fills standardized to 30-day supplies 4,082 Days of Medication total across all patients in 2023 | |||
| Losartan Potassium | 55 | $13.72 | ▼ Less than typical |
About Losartan Potassium: Losartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. Show more ▾ It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Losartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily. An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II. In 2023, this provider wrote 55 Medicare prescriptions for Losartan Potassium, about half the volume of the typical North Carolina prescriber of this medication (102). Medicare paid an average of $13.72 per fill, versus $10.52 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 158.1 30-Day Fills standardized to 30-day supplies 4,744 Days of Medication total across all patients in 2023 | |||
| Bumetanide | 42 | $82.23 | ▲ More than typical |
About Bumetanide: Bumetanide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. Show more ▾ This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. Bumetanide is a water pill (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt. A sulfamyl diuretic. In 2023, this provider wrote 42 Medicare prescriptions for Bumetanide, about 1.4 times the volume of the typical North Carolina prescriber of this medication (29). Medicare paid an average of $82.23 per fill, versus $56.41 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 93.7 30-Day Fills standardized to 30-day supplies 2,770 Days of Medication total across all patients in 2023 | |||
| EliquisApixaban | 40 | $855.76 | ▼ Less than typical |
About Eliquis: Apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery. Show more ▾ With atrial fibrillation, part of the heart does not beat the way it should. This can lead to blood clots forming, which can travel to other parts of your body (such as the lungs or legs) or increase your risk for stroke. In the United States, apixaban is also approved to treat certain types of blood clots (deep vein thrombosis-DVT, pulmonary embolus-PE) and to prevent them from forming again. Apixaban is an anticoagulant that works by blocking certain clotting proteins in your blood. In 2023, this provider wrote 40 Medicare prescriptions for Eliquis, about half the volume of the typical North Carolina prescriber of this medication (84). Medicare paid an average of $855.76 per fill, versus $781.62 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 58 30-Day Fills standardized to 30-day supplies 1,738 Days of Medication total across all patients in 2023 | |||
| Tadalafil | 37 | $443.36▼ below NC avg | ▲ More than typical |
About Tadalafil: Tadalafil is used to treat high blood pressure in the lungs (pulmonary hypertension). Show more ▾ It works by relaxing and widening the blood vessels in your lungs which allows the blood to flow more easily. Decreasing high blood pressure in the lungs allows your heart and lungs to work better and improves your ability to exercise. A carboline derivative and PHOSPHODIESTERASE 5 INHIBITOR that is used primarily to treat ERECTILE DYSFUNCTION; BENIGN PROSTATIC HYPERPLASIA and PRIMARY PULMONARY HYPERTENSION. In 2023, this provider wrote 37 Medicare prescriptions for Tadalafil, about 1.3 times the volume of the typical North Carolina prescriber of this medication (29). Medicare paid an average of $443.36 per fill, versus $551.41 statewide. How often this provider prescribes it This provider prescribes this medication more often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 53 30-Day Fills standardized to 30-day supplies 1,510 Days of Medication total across all patients in 2023 | |||
| Rosuvastatin Calcium | 35 | $16.38▼ below NC avg | ▼ Less than typical |
About Rosuvastatin Calcium: Rosuvastatin is used along with a proper diet to help lower bad cholesterol and fats (such as LDL, triglycerides) and raise good cholesterol (HDL) in the blood. Show more ▾ It belongs to a group of drugs known as statins. It works by reducing the amount of cholesterol made by the liver. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps to prevent strokes and heart attacks. In addition to eating a proper diet (such as a low cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Talk with your doctor for more details. A HYDROXYMETHYLGLUTARYL-COA-REDUCTASE INHIBITOR, or statin, that reduces the plasma concentrations of LDL-CHOLESTEROL; APOLIPOPROTEIN B, and TRIGLYCERIDES while increasing HDL-CHOLESTEROL levels in patients with HYPERCHOLESTEROLEMIA and those at risk for CARDIOVASCULAR DISEASES. In 2023, this provider wrote 35 Medicare prescriptions for Rosuvastatin Calcium, about a third of the volume of the typical North Carolina prescriber of this medication (102). Medicare paid an average of $16.38 per fill, versus $19.73 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 85 30-Day Fills standardized to 30-day supplies 2,544 Days of Medication total across all patients in 2023 | |||
| Atorvastatin Calcium | 32 | $10.91▼ below NC avg | ▼ Less than typical |
About Atorvastatin Calcium: Atorvastatin is used along with a proper diet to help lower bad cholesterol and fats (such as LDL, triglycerides) and raise good cholesterol (HDL) in the blood. Show more ▾ It belongs to a group of drugs known as statins. It works by reducing the amount of cholesterol made by the liver. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details. A pyrrole and heptanoic acid derivative, HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITOR (statin), and ANTICHOLESTEREMIC AGENT that is used to reduce serum levels of LDL-CHOLESTEROL; APOLIPOPROTEIN B; and TRIGLYCERIDES. It is used to increase serum levels of HDL-CHOLESTEROL in the treatment of HYPERLIPIDEMIAS, and for the prevention of CARDIOVASCULAR DISEASES in patients with multiple risk factors. In 2023, this provider wrote 32 Medicare prescriptions for Atorvastatin Calcium, about 19% of the volume of the typical North Carolina prescriber of this medication (170). Medicare paid an average of $10.91 per fill, versus $11.92 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 94 30-Day Fills standardized to 30-day supplies 2,820 Days of Medication total across all patients in 2023 | |||
| Torsemide | 32 | $47.10 | ≈ Typical |
About Torsemide: Torsemide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. Show more ▾ This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Torsemide is a water pill (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt. A pyridine and sulfonamide derivative that acts as a sodium-potassium chloride symporter inhibitor (loop diuretic). It is used for the treatment of EDEMA associated with CONGESTIVE HEART FAILURE; CHRONIC RENAL INSUFFICIENCY; and LIVER DISEASES. It is also used for the management of HYPERTENSION. In 2023, this provider wrote 32 Medicare prescriptions for Torsemide, about 89% of the volume of the typical North Carolina prescriber of this medication (36). Medicare paid an average of $47.10 per fill, versus $26.34 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 76.8 30-Day Fills standardized to 30-day supplies 2,305 Days of Medication total across all patients in 2023 | |||
| Warfarin Sodium | 22 | $28.54 | ▼ Less than typical |
About Warfarin Sodium: This medication is used to treat blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE) and/or to prevent new clots from forming in your body. Show more ▾ Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack. Conditions that increase your risk of developing blood clots include a certain type of irregular heart rhythm (atrial fibrillation), heart valve replacement, recent heart attack, and certain surgeries (such as hip/knee replacement). Warfarin is commonly called a blood thinner, but the more correct term is anticoagulant. It helps to keep blood flowing smoothly in your body by decreasing the amount of certain substances (clotting proteins) in your blood. An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide. In 2023, this provider wrote 22 Medicare prescriptions for Warfarin Sodium, about half the volume of the typical North Carolina prescriber of this medication (40). Medicare paid an average of $28.54 per fill, versus $13.29 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 42.1 30-Day Fills standardized to 30-day supplies 1,250 Days of Medication total across all patients in 2023 | |||
| LetairisAmbrisentan | 21 | $13,463.11 | ≈ Typical |
About Letairis: Ambrisentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension). Show more ▾ This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the effects of endothelin-1, thereby helping to decrease the blood pressure in the lungs, slow the worsening of symptoms, and improve your ability to exercise. In 2023, this provider wrote 21 Medicare prescriptions for Letairis, about 78% of the volume of the typical North Carolina prescriber of this medication (27). Medicare paid an average of $13,463.11 per fill, versus $11,813.41 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 21 30-Day Fills standardized to 30-day supplies 630 Days of Medication total across all patients in 2023 | |||
| Lisinopril | 20 | $7.46 | ▼ Less than typical |
About Lisinopril: Lisinopril is used to treat high blood pressure. Show more ▾ Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure and to improve survival after a heart attack. Lisinopril belongs to a class of drugs known as ACE inhibitors. It works by relaxing blood vessels so blood can flow more easily. One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors), orally active, that has been used in the treatment of hypertension and congestive heart failure. In 2023, this provider wrote 20 Medicare prescriptions for Lisinopril, about 18% of the volume of the typical North Carolina prescriber of this medication (111). Medicare paid an average of $7.46 per fill, versus $7.03 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 60 30-Day Fills standardized to 30-day supplies 1,800 Days of Medication total across all patients in 2023 | |||
| Orenitram ErTreprostinil Diolamine | 18 | $5,565.99▼ below NC avg | ▼ Less than typical |
About Orenitram Er: This medication is used to treat a type of high blood pressure in the lungs (pulmonary arterial hypertension). Show more ▾ Treprostinil helps to delay disease worsening and increase your ability to exercise. It works by relaxing and widening the blood vessels (arteries) in the lungs and other parts of the body so that blood can flow more easily. This medication belongs to a class of drugs known as vasodilators. In 2023, this provider wrote 18 Medicare prescriptions for Orenitram Er, about half the volume of the typical North Carolina prescriber of this medication (31). Medicare paid an average of $5,565.99 per fill, versus $7,495.41 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 18 30-Day Fills standardized to 30-day supplies 540 Days of Medication total across all patients in 2023 | |||
| Eplerenone | 17 | $132.67 | ≈ Typical |
About Eplerenone: This medication is used alone or in combination with other medicines to treat high blood pressure. Show more ▾ It works by blocking a chemical (aldosterone) in your body which in turn lowers the amount of sodium and water the body retains. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. It is also used to treat congestive heart failure following a heart attack. A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION. In 2023, this provider wrote 17 Medicare prescriptions for Eplerenone, about 89% of the volume of the typical North Carolina prescriber of this medication (19). Medicare paid an average of $132.67 per fill, versus $123.66 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 45 30-Day Fills standardized to 30-day supplies 1,263 Days of Medication total across all patients in 2023 | |||
| Tyvaso DpiTreprostinil | 16 | $23,445.56▼ below NC avg | ≈ Typical |
About Tyvaso Dpi: This medication is used to treat a type of high blood pressure in the lungs (pulmonary arterial hypertension). Show more ▾ Treprostinil helps to improve symptoms such as shortness of breath and tiredness. It works by relaxing and widening the blood vessels (arteries) in the lungs and other parts of the body so that blood can flow more easily. This medication belongs to a class of drugs known as vasodilators. In 2023, this provider wrote 16 Medicare prescriptions for Tyvaso Dpi, about 84% of the volume of the typical North Carolina prescriber of this medication (19). Medicare paid an average of $23,445.56 per fill, versus $23,804.60 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 16 30-Day Fills standardized to 30-day supplies 448 Days of Medication total across all patients in 2023 | |||
| Pantoprazole Sodium | 15 | $20.50 | ▼ Less than typical |
About Pantoprazole Sodium: Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). Show more ▾ It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER. In 2023, this provider wrote 15 Medicare prescriptions for Pantoprazole Sodium, about 19% of the volume of the typical North Carolina prescriber of this medication (80). Medicare paid an average of $20.50 per fill, versus $16.84 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 27 30-Day Fills standardized to 30-day supplies 810 Days of Medication total across all patients in 2023 | |||
| VyndamaxTafamidis | 13 | $20,287.75▼ below NC avg | ▼ Less than typical |
About Vyndamax: This medication is used to treat a certain type of heart failure (transthyretin-mediated amyloidosis). Show more ▾ It is used to help prevent the heart failure from getting worse and needing treatment in a hospital. Tafamidis works by slowing the buildup of a certain protein (amyloid fibrils) that causes heart problems. In 2023, this provider wrote 13 Medicare prescriptions for Vyndamax, about a third of the volume of the typical North Carolina prescriber of this medication (34). Medicare paid an average of $20,287.75 per fill, versus $21,773.16 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 13 30-Day Fills standardized to 30-day supplies 390 Days of Medication total across all patients in 2023 | |||
| Spiriva HandihalerTiotropium Bromide | 13 | $757.38 | ▼ Less than typical |
About Spiriva Handihaler: Tiotropium is used to control and prevent symptoms (such as wheezing, shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis and emphysema). Show more ▾ It works by relaxing the muscles around the airways so that they open up and you can breathe more easily. Tiotropium belongs to a class of drugs known as anticholinergics. Controlling symptoms of breathing problems can decrease time lost from work or school. This medication must be used regularly to be effective. It does not work right away and should not be used to relieve sudden breathing problems. If wheezing or sudden shortness of breath occurs, use your quick-relief inhaler (such as albuterol, also called salbutamol in some countries) as prescribed. A scopolamine derivative and CHOLINERGIC ANTAGONIST that functions as a BRONCHODILATOR AGENT. It is used in the treatment of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. In 2023, this provider wrote 13 Medicare prescriptions for Spiriva Handihaler, about half the volume of the typical North Carolina prescriber of this medication (22). Medicare paid an average of $757.38 per fill, versus $721.72 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 18 30-Day Fills standardized to 30-day supplies 540 Days of Medication total across all patients in 2023 | |||
| Hydrochlorothiazide | 12 | $3.71▼ below NC avg | ▼ Less than typical |
About Hydrochlorothiazide: This medication is used to treat high blood pressure. Show more ▾ Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydrochlorothiazide belongs to a class of drugs known as diuretics/water pills. It works by causing you to make more urine. This helps your body get rid of extra salt and water. This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet. A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism. In 2023, this provider wrote 12 Medicare prescriptions for Hydrochlorothiazide, about 15% of the volume of the typical North Carolina prescriber of this medication (82). Medicare paid an average of $3.71 per fill, versus $4.90 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 36 30-Day Fills standardized to 30-day supplies 1,080 Days of Medication total across all patients in 2023 | |||
| Famotidine | 11 | $17.03▼ below NC avg | ≈ Typical |
About Famotidine: Famotidine is used to treat ulcers of the stomach and intestines and to prevent intestinal ulcers from coming back after they have healed. Show more ▾ This medication is also used to treat certain stomach and throat (esophagus) problems (such as erosive esophagitis, gastroesophageal reflux disease-GERD, Zollinger-Ellison syndrome). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as cough that doesn't go away, stomach pain, heartburn, and difficulty swallowing. Famotidine belongs to a class of drugs known as H2 blockers. This medication is also available without a prescription. It is used to prevent and treat heartburn and other symptoms caused by too much acid in the stomach (acid indigestion). If you are taking this medication for self-treatment, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist. A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion. In 2023, this provider wrote 11 Medicare prescriptions for Famotidine, about the same volume as the typical North Carolina prescriber of this medication (12). Medicare paid an average of $17.03 per fill, versus $22.57 statewide. How often this provider prescribes it This provider's prescribing volume for this medication is in line with the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill This provider's average cost per fill is below the NC average for this medication. 33 30-Day Fills standardized to 30-day supplies 990 Days of Medication total across all patients in 2023 | |||
| VeltassaPatiromer Calcium Sorbitex | 11 | $1,312.85 | ▼ Less than typical |
About Veltassa: This medication is used to treat a high level of potassium in your blood. Show more ▾ Too much potassium in your blood can sometimes cause heart rhythm problems. Patiromer helps get rid of extra potassium by binding to it. The potassium then passes out of your body in your stool. In 2023, this provider wrote 11 Medicare prescriptions for Veltassa, about half the volume of the typical North Carolina prescriber of this medication (19). Medicare paid an average of $1,312.85 per fill, versus $891.85 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 11 30-Day Fills standardized to 30-day supplies 308 Days of Medication total across all patients in 2023 | |||
| XareltoRivaroxaban | 11 | $1,038.75 | ▼ Less than typical |
About Xarelto: Rivaroxaban is used to prevent blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip or knee replacement surgery. Show more ▾ It is also used to prevent blood clots from forming in high-risk patients with limited mobility during their hospital stay and after discharge. In addition, rivaroxaban is used to treat blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE) and to prevent the blood clots from forming again. Rivaroxaban may be used in children to prevent blood clots from forming after a certain heart surgery (Fontan procedure). Rivaroxaban is an anticoagulant that works by blocking certain clotting proteins in your blood. A morpholine and thiophene derivative that functions as a FACTOR XA INHIBITOR and is used in the treatment and prevention of DEEP-VEIN THROMBOSIS and PULMONARY EMBOLISM. It is also used for the prevention of STROKE and systemic embolization in patients with non-valvular ATRIAL FIBRILLATION, and for the prevention of atherothrombotic events in patients after an ACUTE CORONARY SYNDROME. In 2023, this provider wrote 11 Medicare prescriptions for Xarelto, about a quarter of the volume of the typical North Carolina prescriber of this medication (43). Medicare paid an average of $1,038.75 per fill, versus $850.84 statewide. How often this provider prescribes it This provider prescribes this medication less often than the average NC prescriber. Utilization reflects practice size as well as clinical preference. What Medicare paid per fill Gross Part D cost per fill; not the patient's out-of-pocket price. 21 30-Day Fills standardized to 30-day supplies 630 Days of Medication total across all patients in 2023 | |||
About this data. The prescription history for DAVID CHANG ISHIZAWAR M.D. is compiled from the Centers for Medicare & Medicaid Services (CMS) Medicare Part D Prescriber Public Use File for calendar year 2023, the most recent federal release. Figures cover prescriptions filled for Medicare Part D beneficiaries only; prescriptions under private insurance, Medicaid, or self-pay plans are not included. Because prescribing decisions are generally consistent across coverage types, this record offers a useful view of the overall Advanced Heart Failure and Transplant Cardiology prescribing approach at this Raleigh, NC practice.
Reading the costs. Drug costs are gross amounts paid to pharmacies under Part D, including both plan and beneficiary payments. They are not the price a patient pays at the pharmacy counter. Medications with fewer than 11 claims are excluded from the federal source data, and state comparisons use the average volume among NC prescribers of the same medication. Always confirm current medications and costs directly with the provider and your plan.
