CLAYTON JOEL SHAMBLIN M.D.
NPI 1306929799
Internal Medicine - Pulmonary Disease in Simpsonville, SC

Q: What is Clayton Shamblin's NPI number?

The NPI number for Clayton Shamblin is 1306929799. It was assigned to this individual provider in the NPPES registry on October 23, 2006.

Q: What is Clayton Shamblin's specialty?

The primary specialty registered for this NPI is Internal Medicine, specializing in Pulmonary Disease, with taxonomy code 207RP1001X.

Q: When was this NPI record last updated?

The NPPES record for Clayton Shamblin was last updated on December 10, 2025. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 10 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.

Active since October 23, 2006PECOS EnrolledAccepts Medicare Assignment

727 SE MAIN ST STE 120, SIMPSONVILLE, SC 29681(864) 454-6700(864) 454-6705 Get Directions Write a Review

NPPES record last updated: December 10, 2025. Verified against the NPPES registry weekly; last sync: November 01, 2026.

Record update history: Dec 10, 2025, May 12, 2021 (2 updates tracked since 2021).

On this page

About Clayton Joel Shamblin M.d. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

CLAYTON JOEL SHAMBLIN M.D. (NPI 1306929799) is an individual pulmonary disease provider in Simpsonville, South Carolina, licensed in South Carolina (29001) and active in the NPI registry since October 2006. He is enrolled in Medicare PECOS, is affiliated with Prisma Health Baptist Easley Hospital, and maintains a secondary practice location in Greenville.

NPPES Registry Identity

NPI1306929799

Entity TypeIndividualMale

Primary Taxonomy207RP1001X

Provider Legal NameCLAYTON JOEL SHAMBLINCredential: M.D.

Location Address727 SE MAIN ST STE 120Simpsonville, SC 29681-3248

Mailing Address300 E Mcbee Ave Fl 4Greenville, SC 29601-2842 · (864) 522-8603

Phone(864) 454-6700

Fax(864) 454-6705

Sole ProprietorNo

Medical School CMSWest Virginia University School Of MedicineGraduated 2006

Enumeration DateOctober 23, 2006

Last NPPES UpdateDecember 10, 20252 updates tracked since enumeration

NPPES CertifiedDecember 10, 2025

✔ NPI 1306929799 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses 2

★ Primary SpecialtyInternal Medicine · Pulmonary DiseaseAllopathic & Osteopathic Physicians

Taxonomy Code207RP1001X

License✔ Licensed in SC · 29001

Definition

An internist who treats diseases of the lungs and airways. The pulmonologist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational and environmental diseases, bronchitis, sleep disorders, emphysema and other complex disorders of the lungs.

Also ListedInternal Medicine · Critical Care MedicineTaxonomy 207RC0200X · License 29001 (SC)

727 SE MAIN ST STE 120, Simpsonville, SC 29681

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Secondary Practice Location 1

Location 1200 Patewood Dr Ste B300Greenville, SC 29615-6338 · Phone (864) 454-4200 · Fax (864) 454-4205

Other Identifiers 1

Medicaid290018SC

Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Ambetter from Absolute Total Care, Ambetter Health, Ambetter of North Carolina and more.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Clayton Joel Shamblin M.d. is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID8426101734

PECOS Enrollment IDI20090804000730

Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

Medicare enrollment records show Clayton Shamblin reassigns Medicare billing to 3 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Prisma Health University Medical Group

8.8 mi

Internal Medicine

1025 VERDAE BLVD, SUITE A
Greenville, SC 29607

Reassigned Medicare billing, South Carolina enrollment
3,281 clinicians in this Medicare group

NPI 1083787006 (864) 242-4683

Greenville Health System

10 mi

General Acute Care Hospital

200 PATEWOOD DR, SUITE C 300
Greenville, SC 29615

Reassigned Medicare billing, South Carolina enrollment
735 clinicians in this Medicare group

NPI 1184049041 (864) 454-8272

Prisma Health Medical Group-Midlands

76 mi

Interventional Cardiology

300 PALMETTO HEALTH PKWY STE 400
Columbia, SC 29212

Reassigned Medicare billing, South Carolina enrollment
1,466 clinicians in this Medicare group

NPI 1003307166 (803) 765-0871

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Areas of Expertise CMS Part B claims 15

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Test to measure expiratory airflow and volume 94010

This test, known as spirometry, assesses how well your lungs work. It measures how much air you can inhale, how much you can exhale and how quickly you can exhale. It's non-invasive and helps diagnose conditions like asthma or COPD.

82 services76 patients

Critical care, first 30-74 minutes 99291

Critical care involves immediate and constant attention by a team of specially-trained health professionals. It's for patients with life-threatening conditions, requiring first 30-74 minutes of intense monitoring and treatment.

80 services44 patients

Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214

This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.

74 services65 patients

Test to examine how well the lungs exchange gases 94729

This is a test called a pulmonary function test, which helps understand the efficiency of your lungs. It measures how much air your lungs can hold, how quickly you can move air in and out of your lungs, and how well your lungs put oxygen into and remove carbon dioxide from your blood.

72 services65 patients

Established patient office or other outpatient visit with high level of medical decision making, if using time, 40 minutes or more 99215

This service involves a follow-up appointment for existing patients, lasting between 40 to 54 minutes. During this time, your healthcare provider will assess your current health status, discuss any changes or concerns, review your treatment plan, and answer any questions you may have.

67 services47 patients

Test for exercise-induced lung stress 94618

An exercise-induced lung stress test assesses how your lungs respond to physical activity. During the test, you'll exercise on a treadmill or stationary bike while your heart rate, breathing, blood pressure, and oxygen levels are monitored. This helps identify any abnormal lung responses to exercise.

66 services47 patients

Subsequent hospital care with moderate levelof medical decision making, if using time, at least 50 minutes 99233

Follow-up hospital inpatient care per day typically involves a 35-minute check-up by your healthcare provider. This service includes monitoring your health progress, adjusting your treatment plan if needed, and answering any questions you may have about your condition or care.

34 services23 patients

Subsequent hospital care with straightforward or low level of medical decision making, per day, if using time, at least 25 minutes 99231

Follow-up hospital inpatient care is a daily service where a healthcare professional checks on your health progress during your hospital stay. Each session typically lasts 15 minutes, involving updates on your condition and adjustments to your treatment plan, if necessary.

28 services18 patients

Irrigation and suction of lung airways to obtain cells using an endoscope 31624

This is a procedure where a thin, flexible tube called an endoscope is inserted through your mouth into the lungs. A small amount of saline is then introduced to wash the airways. The fluid, along with cells from the lung, is suctioned back for analysis.

21 services21 patients

Established patient office or other outpatient visit with low level od decision making, if using time, 20 minutes or more 99213

This is a routine visit for patients who have already been seen by the healthcare provider. During this approximately 20-29 minute appointment, your health status will be evaluated and any necessary treatments or tests will be discussed. It's a chance to address any health concerns you may have.

19 services18 patients

New patient office or other outpatient visit with moderate level of medical decision making, if using time, 45 minutes or more 99204

This is a first-time office or outpatient visit lasting between 45-59 minutes. The healthcare provider evaluates your health, discusses your medical history, and may suggest further tests or treatments. It's an opportunity to ask questions and understand your health better.

18 services18 patients

Test to determine lung volumes using sensors 94726

This test, called spirometry, measures lung capacity using sensors. You breathe into a mouthpiece attached to a device that records the amount and rate of air you inhale and exhale. It helps diagnose and monitor lung conditions.

17 services17 patients

Initial hospital care with moderate level of medical decision making, if using time, at least 75 minutes 99223

Initial hospital inpatient care per day, typically 70 minutes, refers to the daily medical service provided to patients admitted to the hospital. This includes a comprehensive evaluation, diagnosis, treatment plan, and monitoring of your health condition. It ensures your well-being during your hospital stay.

17 services17 patients

X-ray of chest, 2 views 71046

A chest X-ray, 2 views, is a quick, painless test that creates pictures of the structures inside your chest, such as your heart, lungs, and blood vessels. Two different angles are used to get a comprehensive view. This helps in diagnosing conditions like pneumonia, heart problems, or lung cancer.

13 services13 patients

Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes 99232

Follow-up hospital inpatient care involves daily check-ups while you're admitted in the hospital. Typically, a healthcare provider spends about 25 minutes each day reviewing your condition, adjusting treatment if needed, and answering any questions you might have.

13 services12 patients

Hospital Affiliations CMS Care Compare 5

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Prisma Health Baptist Easley Hospital

Acute Care Hospitals · Easley, SC

3/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number420015

Location200 Fleetwood DriveEasley, SC 29640 · Pickens County

Emergency services

Prisma Health Greer Memorial Hospital

Acute Care Hospitals · Spartanburg, SC

4/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number420033

Location1413 John B White Sr Blvd Suite DSpartanburg, SC 29306 · Spartanburg County

Emergency services Birthing friendly

Prisma Health Hillcrest Hospital

Acute Care Hospitals · Simpsonville, SC

3/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number420037

Location741 South East Main StreetSimpsonville, SC 29681 · Greenville County

Emergency services

Prisma Health Laurens County Hospital

Acute Care Hospitals · Clinton, SC

3/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number420038

Location22725 Highway 76 EastClinton, SC 29325 · Laurens County

Emergency services Birthing friendly

Prisma Health Greenville Memorial Hospital

Acute Care Hospitals · Greenville, SC

3/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number420078

Location701 Grove RoadGreenville, SC 29605 · Greenville County

Birthing friendly

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 29681 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient

$124.04 typical visit price

range $53.57 – $163.84

Typical copayment $31.01 (range $13.39 – $40.96)

Most-billed visit code 99204

Established Patient

$95.12 typical visit price

range $16.96 – $133.52

Typical copayment $23.78 (range $4.24 – $33.38)

Most-billed visit code 99214

Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Referred Medical Equipment & Supplies CMS DME claims 29

Durable medical equipment, devices and supplies this provider ordered from DME suppliers for patients, from Medicare fee-for-service claims.

Supplies for maintenance of non-insulin drug infusion catheter, per week (list drugs separately) A4221

DME-Other DME · category DE017N

1 supplier20 claims80 services$18.92 avg. paid by Medicare

Infusion supplies for external drug infusion pump, per cassette or bag (list drugs separately) A4222

DME-Medical/Surgical Supplies · category DA000N

1 supplier20 claims424 services$37.84 avg. paid by Medicare

Tubing with integrated heating element for use with positive airway pressure device A4604

DME-Other DME · category DE001N

11 suppliers107 claims107 services$34.02 avg. paid by Medicare

Full face mask used with positive airway pressure device, each A7030

DME-Other DME · category DE001N

8 suppliers48 claims48 services$72.54 avg. paid by Medicare

Face mask interface, replacement for full face mask, each A7031

DME-Other DME · category DE001N

8 suppliers53 claims124 services$26.37 avg. paid by Medicare

Cushion for use on nasal mask interface, replacement only, each A7032

DME-Other DME · category DE001N

9 suppliers36 claims199 services$17.03 avg. paid by Medicare

Pillow for use on nasal cannula type interface, replacement only, pair A7033

DME-Other DME · category DE001N

11 suppliers37 claims185 services$13.19 avg. paid by Medicare

Nasal interface (mask or cannula type) used with positive airway pressure device, with or without head strap A7034

DME-Other DME · category DE001N

13 suppliers68 claims68 services$48.34 avg. paid by Medicare

Headgear used with positive airway pressure device A7035

DME-Other DME · category DE001N

12 suppliers74 claims74 services$15.72 avg. paid by Medicare

Chinstrap used with positive airway pressure device A7036

DME-Other DME · category DE001N

4 suppliers12 claims12 services$9.23 avg. paid by Medicare

Tubing used with positive airway pressure device A7037

DME-Other DME · category DE001N

7 suppliers14 claims14 services$9.74 avg. paid by Medicare

Filter, disposable, used with positive airway pressure device A7038

DME-Other DME · category DE001N

14 suppliers123 claims614 services$1.73 avg. paid by Medicare

Water chamber for humidifier, used with positive airway pressure device, replacement, each A7046

DME-Other DME · category DE001N

13 suppliers54 claims54 services$11.85 avg. paid by Medicare

Portable gaseous oxygen system, rental; includes portable container, regulator, flowmeter, humidifier, cannula or mask, and tubing E0431

DME-Oxygen and Supplies · category DC000N

6 suppliers79 claims81 services$15.99 avg. paid by Medicare

Portable oxygen contents, gaseous, 1 month's supply = 1 unit E0443

DME-Oxygen and Supplies · category DC000N

3 suppliers25 claims25 services$37.13 avg. paid by Medicare

Respiratory assist device, bi-level pressure capability, without backup rate feature, used with noninvasive interface, e.g., nasal or facial mask (intermittent assist device with continuous positive airway pressure device) E0470

DME-Other DME · category DE001N

4 suppliers17 claims18 services$68.64 avg. paid by Medicare

Humidifier, heated, used with positive airway pressure device E0562

DME-Other DME · category DE001N

2 suppliers17 claims19 services$11.00 avg. paid by Medicare

Nebulizer, with compressor E0570

DME-Other DME · category DE000N

3 suppliers27 claims28 services$3.12 avg. paid by Medicare

Ultrasonic/electronic aerosol generator with small volume nebulizer E0574

DME-Other DME · category DE000N

2 suppliers12 claims12 services$32.74 avg. paid by Medicare

Continuous positive airway pressure (cpap) device E0601

DME-Other DME · category DE001N

5 suppliers61 claims63 services$24.79 avg. paid by Medicare

Oxygen concentrator, single delivery port, capable of delivering 85 percent or greater oxygen concentration at the prescribed flow rate E1390

DME-Oxygen and Supplies · category DC002N

9 suppliers168 claims170 services$67.24 avg. paid by Medicare

Portable oxygen concentrator, rental E1392

DME-Oxygen and Supplies · category DC002N

5 suppliers53 claims53 services$34.10 avg. paid by Medicare

Injection, treprostinil, 1 mg J3285

Treatment-Injections and Infusions (nononcologic) · category RI026N

1 supplier12 claims1,120 services$44.84 avg. paid by Medicare

Arformoterol, inhalation solution, fda approved final product, non-compounded, administered through dme, unit dose form, 15 micrograms J7605

DME-Drugs Administered Through DME · category DG006N

4 suppliers24 claims1,680 services$4.71 avg. paid by Medicare

Albuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose, 1 mg J7613

DME-Drugs Administered Through DME · category DG006N

9 suppliers20 claims4,609 services$0.03 avg. paid by Medicare

Budesonide, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, up to 0.5 mg J7626

DME-Drugs Administered Through DME · category DG000N

5 suppliers25 claims1,860 services$0.83 avg. paid by Medicare

Treprostinil, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, 1.74 mg J7686

DME-Drugs Administered Through DME · category DG004N

3 suppliers35 claims980 services$550.32 avg. paid by Medicare

Infusion pump used for uninterrupted parenteral administration of medication, (e.g., epoprostenol or treprostinol) K0455

DME-Other DME · category DE000N

1 supplier21 claims21 services$250.35 avg. paid by Medicare

Pharmacy dispensing fee for inhalation drug(s); per 30 days Q0513

DME-Other DME · category DE000N

11 suppliers66 claims66 services$24.43 avg. paid by Medicare

Dollar amounts are the average Medicare paid the supplier per service. They are not the cost to the patient.

Other Providers at the Same Location NPPES 4

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

JULIE LYNN CHIAPPINI APRN

Nurse Practitioner

727 SE MAIN ST STE 120
SIMPSONVILLE, SC 29681

Greenville County (864) 454-6700

DR. MARGO TONEY LANNAN M.D.

Internal Medicine (Pulmonary Disease)

727 SE MAIN ST STE 120
SIMPSONVILLE, SC 29681

Greenville County (864) 454-6700

ROBERT ALEXANDER BREVETTA D.O.

Internal Medicine (Pulmonary Disease)

727 SE MAIN ST STE 120
SIMPSONVILLE, SC 29681

Greenville County (864) 454-6700

DR. MANUEL EULYSSES IZQUIERDO D.O.

Internal Medicine (Critical Care Medicine)

727 SE MAIN ST STE 120
SIMPSONVILLE, SC 29681

Greenville County (864) 454-6700

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Clayton Shamblin's NPI number?

The NPI number for Clayton Shamblin is 1306929799. It was assigned to this individual provider in the NPPES registry on October 23, 2006.

Where is Clayton Shamblin located?

Clayton Shamblin practices at 727 SE Main St Ste 120, Simpsonville, SC 29681. The listed phone number is (864) 454-6700.

What is Clayton Shamblin's specialty?

The primary specialty registered for this NPI is Internal Medicine, specializing in Pulmonary Disease, with taxonomy code 207RP1001X.

Is Clayton Shamblin enrolled in Medicare?

Yes. Clayton Shamblin is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

Which organizations bill Medicare for Clayton Shamblin's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Clayton Shamblin reassigns Medicare benefits to 3 organizations: Prisma Health University Medical Group (Greenville, SC), Greenville Health System (Greenville, SC) and Prisma Health Medical Group-Midlands (Columbia, SC). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Clayton Shamblin's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

What insurance does Clayton Shamblin accept?

Health plans from Ambetter Health, Ambetter from Absolute Total Care, Ambetter of North Carolina, BlueCross BlueShield of South Carolina and InStil Health list Clayton Shamblin as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Clayton Shamblin affiliated with any hospitals?

According to CMS data, Clayton Shamblin is affiliated with Prisma Health Baptist Easley Hospital, Prisma Health Greer Memorial Hospital, Prisma Health Hillcrest Hospital, Prisma Health Laurens County Hospital and Prisma Health Greenville Memorial Hospital.

When was this NPI record last updated?

The NPPES record for Clayton Shamblin was last updated on December 10, 2025. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 10 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.