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SOUTH MAIN CLINIC INC
NPI 1295619831
Family Medicine in Houston, TX

Active since August 05, 2025CLIA 45D1038312 · Waiver
12333 MAIN ST, HOUSTON, TX 77035(713) 729-7600(713) 729-7603 Get Directions Write a Review

NPPES record last updated: May 19, 2026. Verified against the NPPES registry weekly; last sync: August 16, 2026.

Record update history: May 19, 2026, Aug 5, 2025 (2 updates tracked since 2025).

About South Main Clinic Inc NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

SOUTH MAIN CLINIC INC (NPI 1295619831) is a healthcare organization registered as a family medicine in Houston, Texas and active in the NPI registry since August 2025. The organization holds a CLIA Waiver certificate valid through March 15, 2027 and lists Danielle Nichole Brown, Owner, as its authorized official.

NPPES Registry Identity

NPI1295619831
Entity TypeOrganization
Primary Taxonomy207Q00000X
Legal Business NameSOUTH MAIN CLINIC INC
Location Address12333 MAIN STHouston, TX 77035-6205
Mailing Address12333 Main StHouston, TX 77035-6205 · (713) 729-7600 · Fax (713) 729-7603
Phone(713) 729-7600
Fax(713) 729-7603
Organization SubpartNo
Authorized OfficialDanielle Nichole BrownOwner · (281) 753-5509
Enumeration DateAugust 5, 2025
Last NPPES UpdateMay 19, 20262 updates tracked since enumeration
NPPES CertifiedMay 19, 2026
✔ NPI 1295619831 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses 2

★ Primary SpecialtyFamily MedicineAllopathic & Osteopathic Physicians
Taxonomy Code207Q00000X
Definition
Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadth which integrates the biological, clinical, and behavioral sciences. The scope of family medicine is not limited by age, sex, organ system, or disease entity.
Also ListedEmergency MedicineTaxonomy 207P00000X
12333 MAIN ST, Houston, TX 77035
Open in Google Maps ↗

Group Practice 1

Group TaxonomyThis provider is a business group of one or more individual practitioners, who practice with different areas of specialization.193200000X MULTI-SPECIALTY GROUP

CLIA Laboratory Certificates CMS CLIA

Laboratory certificates issued under the Clinical Laboratory Improvement Amendments (CLIA) program, which sets federal quality standards for human laboratory testing in the United States. There is no official CMS crosswalk between CLIA and NPI numbers; these certificates are associated with this NPI by matching facility names, locations and phone numbers in the CMS CLIA registry.

Certificate of Waiver 45D1038312

South Main Clinic · Houston, TX
Active · expires Mar 15, 2027
CLIA Number45D1038312
Laboratory TypeAncillary Testing Site In Health Care Center
Certificate Effective DateMarch 16, 2025
Certificate Expiration DateMarch 15, 2027
Laboratory DirectorDr. Danielle Brown
Laboratory Phone(713) 729-7600
Laboratory LocationSouth Main Clinic12333 Main St, Houston, TX 77035
CLIA data matches this NPI record on: Address Name Phone
This certificate is issued to a laboratory to perform only waived tests.

Other Providers at the Same Location NPPES 3

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

SOUTH MAIN CLINIC, INC
Legal Medicine
12333 MAIN ST
HOUSTON, TX 77035
Harris County (713) 729-7600
MAIN STREET PHYSICIANS GROUP PLLC
Family Medicine
12333 MAIN ST
HOUSTON, TX 77035
Harris County (713) 729-7600
MARIANA RENE GUTIERREZ NP
Nurse Practitioner (Family)
12333 MAIN ST
HOUSTON, TX 77035
Harris County (713) 729-7600

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is South Main Clinic Inc's NPI number?

The NPI number for South Main Clinic Inc is 1295619831. It was assigned to this organization in the NPPES registry on August 5, 2025.

Where is South Main Clinic Inc located?

South Main Clinic Inc is located at 12333 Main St, Houston, TX 77035. The listed phone number is (713) 729-7600.

What is South Main Clinic Inc's specialty?

The primary specialty registered for this NPI is Family Medicine with taxonomy code 207Q00000X.

Does South Main Clinic Inc hold a CLIA laboratory certificate?

Yes. A Certificate of Waiver (number 45D1038312) is associated with this NPI, valid through March 15, 2027. CLIA certificates authorize laboratory testing under the federal Clinical Laboratory Improvement Amendments program.

When was this NPI record last updated?

The NPPES record for South Main Clinic Inc was last updated on May 19, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 3 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.