Recently Updated NPI Information — some details in this NPI profile have been updated in the NPI registry within the last 60 days.

LORI L COOK M.D.
NPI 1255317723
Internal Medicine in Columbia, SC

Q: What is Lori Cook's NPI number?

The NPI number for Lori Cook is 1255317723. It was assigned to this individual provider in the NPPES registry on December 16, 2005. The provider is also known as Lori L Cook.

Q: What is Lori Cook's specialty?

The primary specialty registered for this NPI is Internal Medicine with taxonomy code 207R00000X.

Q: When was this NPI record last updated?

The NPPES record for Lori Cook was last updated on November 3, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 9 days ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.

Active since December 16, 2005PECOS Enrolled

2301 DEVINE ST, COLUMBIA, SC 29205(803) 233-3835(888) 704-7678 Get Directions Write a Review

NPPES record last updated: November 3, 2026. Verified against the NPPES registry weekly; last sync: November 08, 2026.

Record update history: Nov 3, 2026, Nov 30, 2025, Aug 16, 2024 and 4 more (7 updates tracked since 2018).

On this page

About Lori L Cook M.d. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

LORI L COOK M.D. (NPI 1255317723) is an individual internal medicine provider in Columbia, South Carolina, licensed in South Carolina (25742) and active in the NPI registry since December 2005. She is enrolled in Medicare PECOS, is affiliated with Prisma Health Richland Hospital, and is a graduate of University Of South Carolina School Of Medicine (1998).

NPPES Registry Identity

NPI1255317723

Entity TypeIndividualFemale

Primary Taxonomy207R00000X

Provider Legal NameLORI L COOKCredential: M.D.

Location Address2301 DEVINE STColumbia, SC 29205-2403

Mailing Address2301 Devine StColumbia, SC 29205-2403 · (803) 233-3835 · Fax (888) 704-7678

Phone(803) 233-3835

Fax(888) 704-7678

Sole ProprietorNo

Medical School CMSUniversity Of South Carolina School Of MedicineGraduated 1998

Enumeration DateDecember 16, 2005

Last NPPES UpdateNovember 3, 20267 updates tracked since enumeration

NPPES CertifiedNovember 3, 2026

✔ NPI 1255317723 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyInternal MedicineAllopathic & Osteopathic Physicians

Taxonomy Code207R00000X

License✔ Licensed in SC · 25742

Definition

A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults and the elderly. Internists are trained in the diagnosis and treatment of cancer, infections and diseases affecting the heart, blood, kidneys, joints and digestive, respiratory and vascular systems. They are also trained in the essentials of primary care internal medicine, which incorporates an understanding of disease prevention, wellness, substance abuse, mental health and effective treatment of common problems of the eyes, ears, skin, nervous system and reproductive organs.

2301 DEVINE ST, Columbia, SC 29205

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Other Names 1

Other Name (5)Lori L Cook

Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Ambetter from Absolute Total Care, Ambetter Health, Ambetter of North Carolina and more.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Lori L Cook M.d. is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID941267165

PECOS Enrollment IDI20041220000179

Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

Medicare enrollment records show Lori Cook reassigns Medicare billing to 5 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Prisma Health Medical Group-Midlands

0.7 mi

Multi-Specialty

3555 HARDEN STREET EXT STE 300
Columbia, SC 29203

Reassigned Medicare billing, South Carolina enrollment
1,466 clinicians in this Medicare group

NPI 1275988321 (803) 545-5000

Trubalance Diabetes And Metabolic Health LLC

3.3 mi

Internal Medicine

986 KNOX ABBOTT DR
Cayce, SC 29033

Reassigned Medicare billing, South Carolina enrollment
2 clinicians in this Medicare group

NPI 1063354744 (803) 401-5661

Piedmont Physician Network, LLC

69 mi

Internal Medicine

1023 CREEKSIDE MEDICAL DR
York, SC 29745

Reassigned Medicare billing, South Carolina enrollment
175 clinicians in this Medicare group

NPI 1194277186 (803) 684-3730

Medcare Urgent Care Center - Anderson LLC

100 mi

Urgent Care

801 N FANT ST
Anderson, SC 29621

Reassigned Medicare billing, South Carolina enrollment
Medicare enrollment name: Medcare Express - North Charleston LLC
113 clinicians in this Medicare group

NPI 1689004095 (843) 793-6093

Signify Health Medical Associates, PLLC

917 mi

General Practice

4055 VALLEY VIEW LN STE 700
Dallas, TX 75244

Reassigned Medicare billing, South Carolina enrollment
311 clinicians in this Medicare group

NPI 1750845863 (972) 715-3800

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Areas of Expertise CMS Part B claims 22

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Detection test by immunoassay with direct visual observation for influenza virus 87804

This is a test that identifies the influenza virus in your body. It works by using an immunoassay, a method that detects the presence of the virus through an immune response. The results are directly observable, making it a quick and efficient way to diagnose flu.

140 services71 patients

Injection, dexamethasone sodium phosphate, 1 mg J1100

Dexamethasone sodium phosphate is a medication given via injection. It is a type of steroid that helps reduce inflammation and immune responses. It can be used to treat a variety of conditions, such as allergies, skin conditions, arthritis, and more.

126 services14 patients

Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214

This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.

124 services116 patients

Detection test by immunoassay with direct visual observation for severe acute respiratory syndrome coronavirus 2 (covid-19) 87811

This is a test to detect COVID-19, the virus causing severe respiratory illness. It uses a method called immunoassay, which identifies the virus by its unique proteins. The test is directly observed for accuracy. It helps determine if you're currently infected.

68 services68 patients

Injection, ceftriaxone sodium, per 250 mg J0696

Ceftriaxone sodium is an antibiotic injection used to treat a variety of bacterial infections. Each injection contains 250 mg of the medicine. It works by stopping the growth of bacteria in your body.

60 services14 patients

Injection of drug or substance under skin or into muscle 96372

This procedure involves administering medication directly under the skin or into a muscle. A small needle is used to inject the drug, allowing it to be absorbed quickly into the bloodstream. It's a common method for delivering a variety of medications.

51 services38 patients

Established patient office or other outpatient visit with high level of medical decision making, if using time, 40 minutes or more 99215

This service involves a follow-up appointment for existing patients, lasting between 40 to 54 minutes. During this time, your healthcare provider will assess your current health status, discuss any changes or concerns, review your treatment plan, and answer any questions you may have.

47 services43 patients

Automated urinalysis test 81003

An automated urinalysis test is a routine examination that checks your urine for various substances. It can help identify potential health issues such as kidney problems or diabetes. The test uses a machine to analyze a small urine sample, providing quick and accurate results.

45 services43 patients

New patient office or other outpatient visit with moderate level of medical decision making, if using time, 45 minutes or more 99204

This is a first-time office or outpatient visit lasting between 45-59 minutes. The healthcare provider evaluates your health, discusses your medical history, and may suggest further tests or treatments. It's an opportunity to ask questions and understand your health better.

45 services45 patients

Injection, ketorolac tromethamine, per 15 mg J1885

Ketorolac tromethamine is a medication administered through injection, often used to manage moderate to severe pain. Each 15 mg dose helps to reduce hormones causing inflammation and pain in the body. It is not recommended for long-term use.

36 services15 patients

Detection test by immunoassay with direct visual observation for streptococcus, group a (strep) 87880

A detection test by immunoassay for Group A Strep is a quick procedure to identify a bacterial infection in your throat. It involves taking a throat swab and applying it to a test strip, which changes color if Strep bacteria are present.

29 services29 patients

X-ray of chest, 2 views 71046

A chest X-ray, 2 views, is a quick, painless test that creates pictures of the structures inside your chest, such as your heart, lungs, and blood vessels. Two different angles are used to get a comprehensive view. This helps in diagnosing conditions like pneumonia, heart problems, or lung cancer.

26 services26 patients

Established patient office or other outpatient visit with low level od decision making, if using time, 20 minutes or more 99213

This is a routine visit for patients who have already been seen by the healthcare provider. During this approximately 20-29 minute appointment, your health status will be evaluated and any necessary treatments or tests will be discussed. It's a chance to address any health concerns you may have.

26 services26 patients

Influenza vaccine split virus, preservative free 90662

The Influenza Vaccine Split Virus, preservative-free, is a flu shot to protect against the influenza virus. It is made from parts of inactivated flu viruses and doesn't contain preservatives, reducing potential side effects. It helps your body develop immunity to the flu.

22 services22 patients

Administration of influenza virus vaccine G0008

The administration of the influenza virus vaccine, also known as the flu shot, is a simple procedure to protect against the flu. A healthcare provider injects a small dose of the vaccine into your arm. This stimulates your immune system to produce antibodies, which will help your body fight off the flu if exposed.

22 services22 patients

Albuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose, 1 mg J7613

Albuterol is a medication used to treat breathing problems. It is administered as an inhalation solution through a device called DME (Durable Medical Equipment). The solution is FDA-approved and non-compounded. Each unit dose contains 1 mg of the medicine.

21 services13 patients

Inhalation treatment for airway obstruction or sputum production 94640

Inhalation treatment, also known as nebulizer therapy, helps clear airway obstructions and reduce sputum production. It involves breathing in medication through a device, turning it into a mist. This can open up the airways, making breathing easier and helping to cough out mucus.

19 services17 patients

Annual wellness visit, includes a personalized prevention plan of service (pps), subsequent visit G0439

An annual wellness visit is a yearly appointment with your primary care provider to create or update a personalized prevention plan. This plan helps prevent illness based on your current health and risk factors. It's a subsequent visit, meaning it follows an initial assessment.

18 services18 patients

Detection test by immunoassay technique for severe acute respiratory syndrome coronavirus 87426

An immunoassay test for severe acute respiratory syndrome coronavirus is a diagnostic tool. It uses your body's immune response to detect the presence of the virus. It involves taking a sample, usually from your nose or throat, which is then analyzed in a lab for signs of the virus.

16 services16 patients

New patient office or other outpatient visit with a high level of medical decision making, if using time, 60 minutes or more 99205

This is a first-time patient visit where a healthcare professional spends 60-74 minutes with you. It involves a comprehensive evaluation, including your medical history and current health condition. They'll also advise on preventive health measures and formulate a treatment plan if needed.

16 services16 patients

Ipratropium bromide, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram J7644

Ipratropium bromide is a medication used to control symptoms of lung diseases like COPD. Administered through a device called DME (Durable Medical Equipment), it's inhaled directly into the lungs. It's FDA-approved and provided in unit-dose form per milligram.

15 services14 patients

Routine electrocardiogram (ecg) using at least 12 leads with interpretation and report 93000

An electrocardiogram (ECG) is a non-invasive test that records your heart's electrical activity. Using 12 leads attached to your body, it captures data to help identify heart conditions. A doctor interprets the results and provides a report.

12 services12 patients

Hospital Affiliations CMS Care Compare 3

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Prisma Health Richland Hospital

Acute Care Hospitals · Columbia, SC

3/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number420018

Location5 Medical ParkColumbia, SC 29203 · Richland County

Emergency services Birthing friendly

Prisma Health Baptist

Acute Care Hospitals · Columbia, SC

4/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number420086

Location1330 Taylor At Marion StColumbia, SC 29220 · Richland County

Emergency services Birthing friendly

Prisma Health Baptist Parkridge

Acute Care Hospitals · Columbia, SC

5/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number420106

Location400 Palmetto Health ParkwayColumbia, SC 29212 · Lexington County

Emergency services Birthing friendly

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 29205 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient

$124.04 typical visit price

range $53.57 – $163.84

Typical copayment $31.01 (range $13.39 – $40.96)

Most-billed visit code 99204

Established Patient

$95.12 typical visit price

range $16.96 – $133.52

Typical copayment $23.78 (range $4.24 – $33.38)

Most-billed visit code 99214

Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Referred Medical Equipment & Supplies CMS DME claims 3

Durable medical equipment, devices and supplies this provider ordered from DME suppliers for patients, from Medicare fee-for-service claims.

Wheelchair accessory, headrest, cushioned, any type, including fixed mounting hardware, each E0955

DME-Wheelchairs · category DD021N

1 supplier12 claims12 services$11.63 avg. paid by Medicare

Wheelchair accessory, manual swingaway, retractable or removable mounting hardware for joystick, other control interface or positioning accessory E1028

DME-Wheelchairs · category DD021N

1 supplier22 claims30 services$12.07 avg. paid by Medicare

Manual adult size wheelchair, includes tilt in space E1161

DME-Wheelchairs · category DD000N

1 supplier22 claims22 services$149.70 avg. paid by Medicare

Dollar amounts are the average Medicare paid the supplier per service. They are not the cost to the patient.

Other Providers at the Same Location NPPES

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

VITAL STRENGTH INTERNAL MEDICINE

Internal Medicine

2301 DEVINE ST
COLUMBIA, SC 29205

Richland County (803) 622-6480

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Lori Cook's NPI number?

The NPI number for Lori Cook is 1255317723. It was assigned to this individual provider in the NPPES registry on December 16, 2005. The provider is also known as Lori L Cook.

Where is Lori Cook located?

Lori Cook practices at 2301 Devine St, Columbia, SC 29205. The listed phone number is (803) 233-3835.

What is Lori Cook's specialty?

The primary specialty registered for this NPI is Internal Medicine with taxonomy code 207R00000X.

Is Lori Cook enrolled in Medicare?

Yes. Lori Cook is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

Which organizations bill Medicare for Lori Cook's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Lori Cook reassigns Medicare benefits to 5 organizations: Prisma Health Medical Group-Midlands (Columbia, SC), Trubalance Diabetes And Metabolic Health LLC (Cayce, SC), Piedmont Physician Network, LLC (York, SC), Medcare Urgent Care Center - Anderson LLC (Anderson, SC) and Signify Health Medical Associates, PLLC (Dallas, TX). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Lori Cook's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

What insurance does Lori Cook accept?

Health plans from Ambetter Health, Ambetter from Absolute Total Care, Ambetter of North Carolina, BlueCross BlueShield of South Carolina and First Choice Next list Lori Cook as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Lori Cook affiliated with any hospitals?

According to CMS data, Lori Cook is affiliated with Prisma Health Richland Hospital, Prisma Health Baptist and Prisma Health Baptist Parkridge.

When was this NPI record last updated?

The NPPES record for Lori Cook was last updated on November 3, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 9 days ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.