1. Home
  2. Directory
  3. New York
  4. Buffalo
  5. Internal Medicine
  6. NPI Profile

DR. CALE O'KEEFFE M.D.
NPI 1235586553
Internal Medicine in Buffalo, NY

Active since May 17, 2016PECOS EnrolledAccepts Medicare Assignment
462 GRIDER ST DAVID K MILLER BUILDING, INTERNAL MEDICINE RESIDENCY EDUCATION, ECMC,, BUFFALO, NY 14215(716) 898-3897(716) 898-3279 Get Directions Write a Review

NPPES record last updated: July 30, 2025. Verified against the NPPES registry weekly; last sync: November 01, 2026.

Record update history: Nov 8, 2016, May 17, 2016 (2 updates tracked since 2016).

About Dr. Cale O'keeffe M.d. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

DR. CALE O'KEEFFE M.D. (NPI 1235586553) is an individual internal medicine provider in Buffalo, New York, licensed in New York (302110) and active in the NPI registry since May 2016. He is enrolled in Medicare PECOS, is affiliated with Kaleida Health, and is a graduate of Other (2015).

NPPES Registry Identity

NPI1235586553
Entity TypeIndividualMale
Primary Taxonomy207R00000X
Provider Legal NameDR. CALE O'KEEFFECredential: M.D.
Location Address462 GRIDER ST DAVID K MILLER BUILDING, INTERNAL MEDICINE RESIDENCY EDUCATION, ECMC,Buffalo, NY 14215
Mailing Address462 Grider St David K Miller Building, Internal Medicine Residency Education, Ecmc,Buffalo, NY 14215 · (716) 898-3897 · Fax (716) 898-3279
Phone(716) 898-3897
Fax(716) 898-3279
Sole ProprietorNo
Medical School CMSOtherGraduated 2015
Enumeration DateMay 17, 2016
Last NPPES UpdateJuly 30, 20252 updates tracked since enumeration
NPPES CertifiedJuly 30, 2025
✔ NPI 1235586553 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyInternal MedicineAllopathic & Osteopathic Physicians
Taxonomy Code207R00000X
License✔ Licensed in NY · 302110
Definition
A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults and the elderly. Internists are trained in the diagnosis and treatment of cancer, infections and diseases affecting the heart, blood, kidneys, joints and digestive, respiratory and vascular systems. They are also trained in the essentials of primary care internal medicine, which incorporates an understanding of disease prevention, wellness, substance abuse, mental health and effective treatment of common problems of the eyes, ears, skin, nervous system and reproductive organs.
462 GRIDER ST DAVID K MILLER BUILDING, Buffalo, NY 14215
Open in Google Maps ↗

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Dr. Cale O'keeffe M.d. is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID1658618111
PECOS Enrollment IDI20200103001642
Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

2

Medicare enrollment records show Cale O'keeffe reassigns Medicare billing to 2 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Apogee Medical Group, New York, P.C.
Same address
Internal Medicine
462 GRIDER ST
Buffalo, NY 14215
  • Reassigned Medicare billing, New York enrollment
  • Medicare enrollment name: Apogee Medical Group, New York, PC
  • 354 clinicians in this Medicare group
NPI 1841520236 (716) 961-6995
Academic Medicine Services, Inc.
7.0 mi
Internal Medicine
1020 YOUNGS RD
Williamsville, NY 14221
  • Reassigned Medicare billing, New York enrollment
  • 157 clinicians in this Medicare group
NPI 1255394763 (716) 961-9900

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Areas of Expertise CMS Part B claims 4

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Subsequent hospital care with moderate levelof medical decision making, if using time, at least 50 minutes 99233
Follow-up hospital inpatient care per day typically involves a 35-minute check-up by your healthcare provider. This service includes monitoring your health progress, adjusting your treatment plan if needed, and answering any questions you may have about your condition or care.
237 services74 patients
Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes 99232
Follow-up hospital inpatient care involves daily check-ups while you're admitted in the hospital. Typically, a healthcare provider spends about 25 minutes each day reviewing your condition, adjusting treatment if needed, and answering any questions you might have.
77 services36 patients
Hospital discharge day management, more than 30 minutes 99239
Hospital discharge day management over 30 minutes involves a detailed process to ensure a smooth transition from hospital to home. It includes final examinations, discussion of your hospital stay, post-discharge instructions, and coordinating follow-up care.
42 services42 patients
Initial hospital care with moderate level of medical decision making, if using time, at least 75 minutes 99223
Initial hospital inpatient care per day, typically 70 minutes, refers to the daily medical service provided to patients admitted to the hospital. This includes a comprehensive evaluation, diagnosis, treatment plan, and monitoring of your health condition. It ensures your well-being during your hospital stay.
31 services30 patients

Hospital Affiliations CMS Care Compare

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Kaleida Health

Acute Care Hospitals · Buffalo, NY
3/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number330005
Location100 High StreetBuffalo, NY 14210 · Erie County
Emergency services Birthing friendly

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 14215 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient
$126.40 typical visit price
range $54.87 – $166.88
Typical copayment $31.60 (range $13.71 – $41.72)
Most-billed visit code 99204
Established Patient
$97.08 typical visit price
range $17.54 – $136.14
Typical copayment $24.27 (range $4.38 – $34.03)
Most-billed visit code 99214
Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Other Providers at the Same Location NPPES

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

DR. MICHAEL WD PERRAS M.D.
Student in an Organized Health Care Education/Training Program
462 GRIDER ST DAVID K MILLER BUILDING, ERIE COUNTY MEDICAL CENTER INTERNAL MEDICINE RESDENCY O
BUFFALO, NY 14215
Erie County (716) 898-3941

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Cale O'keeffe's NPI number?

The NPI number for Cale O'keeffe is 1235586553. It was assigned to this individual provider in the NPPES registry on May 17, 2016.

Where is Cale O'keeffe located?

Cale O'keeffe practices at 462 Grider St David K Miller Building Internal Medicine Residency Education, Ecmc,, Buffalo, NY 14215. The listed phone number is (716) 898-3897.

What is Cale O'keeffe's specialty?

The primary specialty registered for this NPI is Internal Medicine with taxonomy code 207R00000X.

Is Cale O'keeffe enrolled in Medicare?

Yes. Cale O'keeffe is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

Which organizations bill Medicare for Cale O'keeffe's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Cale O'keeffe reassigns Medicare benefits to 2 organizations: Apogee Medical Group, New York, P.C. (Buffalo, NY) and Academic Medicine Services, Inc. (Williamsville, NY). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Cale O'keeffe's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

Is Cale O'keeffe affiliated with any hospitals?

According to CMS data, Cale O'keeffe is affiliated with Kaleida Health.

When was this NPI record last updated?

The NPPES record for Cale O'keeffe was last updated on July 30, 2025. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 15 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.