DR. MARIO A SANTIAGO M.D.
NPI 1215998976
General Practice in Orlando, FL

Active since March 31, 2006PECOS EnrolledAccepts Medicare Assignment
737 S SEMORAN BLVD, ORLANDO, FL 32807(321) 247-4960 Get Directions Write a Review

NPPES record last updated: February 17, 2026. Verified against the NPPES registry weekly; last sync: July 26, 2026.

Record update history: Mar 21, 2025, Mar 6, 2025, Nov 16, 2022 and 3 more (6 updates tracked since 2020).

About Dr. Mario A Santiago M.d. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

DR. MARIO A SANTIAGO M.D. (NPI 1215998976) is an individual general practice provider in Orlando, Florida, licensed in Florida (ACN648) and active in the NPI registry since March 2006. He is enrolled in Medicare PECOS, is affiliated with Adventhealth Orlando, and is a graduate of Other (2000).

NPPES Registry Identity

NPI1215998976
Entity TypeIndividualMale
Primary Taxonomy208D00000X
Provider Legal NameDR. MARIO A SANTIAGOCredential: M.D.
Location Address737 S SEMORAN BLVDOrlando, FL 32807-3121
Mailing Address6101 Blue Lagoon Dr Ste 200Miami, FL 33126-3168 · (305) 500-2000
Sole ProprietorNo
Medical School CMSOtherGraduated 2000
Enumeration DateMarch 31, 2006
Last NPPES UpdateFebruary 17, 20266 updates tracked since enumeration
NPPES CertifiedFebruary 17, 2026
NPI 1215998976 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

Primary SpecialtyGeneral PracticeAllopathic & Osteopathic Physicians
Taxonomy Code208D00000X
Licenses Licensed in FL · ACN648 Licensed in PR · 14652
Definition
A physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions. Source: National Uniform Claim Committee
737 S SEMORAN BLVD, Orlando, FL 32807

Other Identifiers 2

OtherN0716FL · Medicare
Medicaid101875500FL

Accepted Insurance

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, and ordering and referring status from the CMS PECOS system.

Medicare Enrollment Status

Enrolled in Medicare and accepts Medicare assignment

Dr. Mario A Santiago M.d. is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID4587684832
PECOS Enrollment IDI20151218001780
Eligible to Order & Refer Part B Labs & Imaging Durable Medical Equipment Home Health Agency Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Hospital Affiliations CMS Care Compare

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Adventhealth Orlando

Acute Care Hospitals · Orlando, FL
3/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number100007
Location601 E Rollins StOrlando, FL 32803 · Orange County
Emergency services Birthing friendly

Other Providers at the Same Location NPPES 9

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

Nurse Practitioner (Psychiatric/Mental Health)
737 S SEMORAN BLVD
ORLANDO, FL 32807
General Practice
737 S SEMORAN BLVD
ORLANDO, FL 32807
Nurse Practitioner (Family)
737 S SEMORAN BLVD
ORLANDO, FL 32807
Nurse Practitioner (Family)
737 S SEMORAN BLVD
ORLANDO, FL 32807
Nurse Practitioner (Primary Care)
737 S SEMORAN BLVD
ORLANDO, FL 32807
General Practice
737 S SEMORAN BLVD
ORLANDO, FL 32807
General Practice
737 S SEMORAN BLVD
ORLANDO, FL 32807
Internal Medicine
737 S SEMORAN BLVD
ORLANDO, FL 32807

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Mario Santiago's NPI number?

The NPI number for Mario Santiago is 1215998976. It was assigned to this individual provider in the NPPES registry on March 31, 2006.

Where is Mario Santiago located?

Mario Santiago practices at 737 S Semoran Blvd, Orlando, FL 32807. The listed phone number is (321) 247-4960.

What is Mario Santiago's specialty?

The primary specialty registered for this NPI is General Practice with taxonomy code 208D00000X.

Is Mario Santiago enrolled in Medicare?

Yes. Mario Santiago is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

What insurance does Mario Santiago accept?

Health plans from Molina Healthcare list Mario Santiago as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Mario Santiago affiliated with any hospitals?

According to CMS data, Mario Santiago is affiliated with Adventhealth Orlando.

When was this NPI record last updated?

The NPPES record for Mario Santiago was last updated on February 17, 2026. NPI Profile syncs with the weekly NPPES data releases published by CMS.