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DR. MARIO A SANTIAGO M.D.
NPI 1215998976
General Practice in Orlando, FL

Active since March 31, 2006PECOS EnrolledAccepts Medicare Assignment
737 S SEMORAN BLVD, ORLANDO, FL 32807(321) 247-4960 Get Directions Write a Review

NPPES record last updated: February 17, 2026. Verified against the NPPES registry weekly; last sync: October 25, 2026.

Record update history: Mar 21, 2025, Mar 6, 2025, Nov 16, 2022 and 3 more (6 updates tracked since 2020).

About Dr. Mario A Santiago M.d. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

DR. MARIO A SANTIAGO M.D. (NPI 1215998976) is an individual general practice provider in Orlando, Florida, licensed in Florida (ACN648) and active in the NPI registry since March 2006. He is enrolled in Medicare PECOS, is affiliated with Adventhealth Orlando, and is a graduate of Other (2000).

NPPES Registry Identity

NPI1215998976
Entity TypeIndividualMale
Primary Taxonomy208D00000X
Provider Legal NameDR. MARIO A SANTIAGOCredential: M.D.
Location Address737 S SEMORAN BLVDOrlando, FL 32807-3121
Mailing Address6101 Blue Lagoon Dr Ste 200Miami, FL 33126-3168 · (305) 500-2000
Phone(321) 247-4960
Sole ProprietorNo
Medical School CMSOtherGraduated 2000
Enumeration DateMarch 31, 2006
Last NPPES UpdateFebruary 17, 20266 updates tracked since enumeration
NPPES CertifiedFebruary 17, 2026
✔ NPI 1215998976 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyGeneral PracticeAllopathic & Osteopathic Physicians
Taxonomy Code208D00000X
Licenses✔ Licensed in FL · ACN648✔ Licensed in PR · 14652
Definition
A physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions. Source: National Uniform Claim Committee
737 S SEMORAN BLVD, Orlando, FL 32807
Open in Google Maps ↗

Other Identifiers 2

OtherN0716FL · Medicare
Medicaid101875500FL

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Dr. Mario A Santiago M.d. is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID4587684832
PECOS Enrollment IDI20151218001780
Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

2

Medicare enrollment records show Mario Santiago reassigns Medicare billing to 2 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Centerwell Senior Primary Care (fl) Inc.
Same address
Internal Medicine
737 S SEMORAN BLVD
Orlando, FL 32807
  • Reassigned Medicare billing, Florida enrollment
  • 123 clinicians in this Medicare group
NPI 1558912659 (321) 247-4960
Miami Beach Medical Consultants, LLC.
203 mi
General Practice
1200 ALTON RD
Miami Beach, FL 33139
  • Reassigned Medicare billing, Florida enrollment
  • 86 clinicians in this Medicare group
NPI 1891032819 (305) 534-0076

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Hospital Affiliations CMS Care Compare

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Adventhealth Orlando

Acute Care Hospitals · Orlando, FL
3/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number100007
Location601 E Rollins StOrlando, FL 32803 · Orange County
Emergency services Birthing friendly

Other Providers at the Same Location NPPES 9

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

DANIEL ERIC CAMPBELL CLARK PMHNP-BC
Nurse Practitioner (Psychiatric/Mental Health)
737 S SEMORAN BLVD
ORLANDO, FL 32807
Orange County (407) 851-5121
DAVID SANJUAN MD
General Practice
737 S SEMORAN BLVD
ORLANDO, FL 32807
Orange County (321) 247-4960
JONNATHAN DAVID SOLTERO ARNP
Nurse Practitioner (Family)
737 S SEMORAN BLVD
ORLANDO, FL 32807
Orange County (321) 247-4960
ALEXSANDRA SANTOS KING NP
Nurse Practitioner (Family)
737 S SEMORAN BLVD
ORLANDO, FL 32807
Orange County (321) 247-4960
MS. MARTHA MARIA BONETT APRN
Nurse Practitioner (Primary Care)
737 S SEMORAN BLVD
ORLANDO, FL 32807
Orange County (321) 247-4960
DR. ARELIS RODRIGUEZ CABAN M.D.
General Practice
737 S SEMORAN BLVD
ORLANDO, FL 32807
Orange County (321) 247-4960
DR. JORGE LUIS TORRES MD
General Practice
737 S SEMORAN BLVD
ORLANDO, FL 32807
Orange County (321) 247-4960
CENTERWELL SENIOR PRIMARY CARE (FL) INC.
Internal Medicine
737 S SEMORAN BLVD
ORLANDO, FL 32807
Orange County (321) 247-4960

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Mario Santiago's NPI number?

The NPI number for Mario Santiago is 1215998976. It was assigned to this individual provider in the NPPES registry on March 31, 2006.

Where is Mario Santiago located?

Mario Santiago practices at 737 S Semoran Blvd, Orlando, FL 32807. The listed phone number is (321) 247-4960.

What is Mario Santiago's specialty?

The primary specialty registered for this NPI is General Practice with taxonomy code 208D00000X.

Is Mario Santiago enrolled in Medicare?

Yes. Mario Santiago is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

Which organizations bill Medicare for Mario Santiago's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Mario Santiago reassigns Medicare benefits to 2 organizations: Centerwell Senior Primary Care (fl) Inc. (Orlando, FL) and Miami Beach Medical Consultants, LLC. (Miami Beach, FL). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Mario Santiago's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

Is Mario Santiago affiliated with any hospitals?

According to CMS data, Mario Santiago is affiliated with Adventhealth Orlando.

When was this NPI record last updated?

The NPPES record for Mario Santiago was last updated on February 17, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 8 months ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.