MICHAEL JAMES POLYDEFKIS M.D.
Prescription History 1194768614
Psychiatry & Neurology - Neurology in Baltimore, MD

Active since June 13, 2006PECOS Enrolled
74.39/100
CMS Quality Rating
600 N WOLFE ST, BALTIMORE, MD 21287(410) 955-9441 Get Directions

NPPES record last updated: January 16, 2026. Verified against the NPPES registry weekly; last sync: August 16, 2026.

Medicare Part D Prescription History

Explore the verified Medicare Part D prescription history, volume metrics, and calculated drug costs for MICHAEL JAMES POLYDEFKIS M.D., an active Neurology specialist practicing in Baltimore, MD. Our medical registry currently tracks 13 unique pharmaceutical formulations prescribed by this provider, representing an estimated volume of 294 documented patient claims. Among these therapy options, the most frequently utilized medication is Gabapentin, which accounts for 67 claims alone. Use the table below to sort by claims, cost, or utilization compared with the state average; select any medication for its full profile.

13
Medications
294
Total Claims
352
30-Day Fills
Gabapentin
Most Prescribed · 67 claims
View details
13 medications · 2023 Medicare Part D
Medicare Part D medications prescribed by MICHAEL JAMES POLYDEFKIS M.D. in 2023, with prescription volumes, average cost per fill, and MD state comparisons
Medication Prescriptions (2023)Rx (2023) Avg Cost per FillCost / Fill Vs. Other MD PrescribersVs. MD Avg

About Gabapentin: Gabapentin is used with other medications to prevent and control seizures. Show more ▾

It is also used to relieve nerve pain following shingles (a painful rash due to herpes zoster infection) in adults. Gabapentin is known as an anticonvulsant or antiepileptic drug. A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.

In 2023, this provider wrote 67 Medicare prescriptions for Gabapentin, about the same volume as the typical Maryland prescriber of this medication (66). Medicare paid an average of $31.79 per fill, versus $21.13 statewide.

How often this provider prescribes it

This provider
67
MD average
66.0

This provider's prescribing volume for this medication is in line with the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$31.79
MD average
$21.13

Gross Part D cost per fill; not the patient's out-of-pocket price.

99
30-Day Fills
standardized to 30-day supplies
2,970
Days of Medication
total across all patients in 2023

About Fentanyl: This medication is used to help relieve severe ongoing pain (such as due to cancer). Show more ▾

Fentanyl belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. Do not use the patch form of fentanyl to relieve pain that is mild or that will go away in a few days. This medication is not for occasional (as needed) use. A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)

In 2023, this provider wrote 43 Medicare prescriptions for Fentanyl, about 1.3 times the volume of the typical Maryland prescriber of this medication (33). Medicare paid an average of $323.19 per fill, versus $116.81 statewide.

How often this provider prescribes it

This provider
43
MD average
33.0

This provider prescribes this medication more often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$323.19
MD average
$116.81

Gross Part D cost per fill; not the patient's out-of-pocket price.

43
30-Day Fills
standardized to 30-day supplies
1,290
Days of Medication
total across all patients in 2023

About Privigen: This medication is used to boost the body's natural defense system against infection in persons with a weakened immune system (primary immune deficiency). Show more ▾

Immune globulin contains natural substances called antibodies (a type called IgG) that come from healthy human blood (plasma). These antibodies help protect your body against infections and help you to fight an infection if you get sick. Some immune globulin products may also be used to treat a certain nerve disorder (chronic inflammatory demyelinating polyneuropathy-CIDP).

In 2023, this provider wrote 34 Medicare prescriptions for Privigen, about 1.4 times the volume of the typical Maryland prescriber of this medication (25). Medicare paid an average of $7,972.67 per fill, versus $13,120.99 statewide.

How often this provider prescribes it

This provider
34
MD average
25.0

This provider prescribes this medication more often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$7,972.67
MD average
$13,120.99

This provider's average cost per fill is below the MD average for this medication.

34
30-Day Fills
standardized to 30-day supplies
714
Days of Medication
total across all patients in 2023

About Onpattro: This medication is used to treat nerve problems due to a certain inherited condition (transthyretin-mediated amyloidosis). Show more ▾

This condition causes a protein that your body normally makes (transthyretin-TTR), to change shape and build up in different parts of your body, which can affect the nerves, heart, and gut. This medication works by decreasing the buildup of TTR in your body.

In 2023, this provider wrote 33 Medicare prescriptions for Onpattro, about the same volume as the typical Maryland prescriber of this medication (35). Medicare paid an average of $30,284.50 per fill, versus $29,675.91 statewide.

How often this provider prescribes it

This provider
33
MD average
35.0

This provider's prescribing volume for this medication is in line with the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$30,284.50
MD average
$29,675.91

Gross Part D cost per fill; not the patient's out-of-pocket price.

33
30-Day Fills
standardized to 30-day supplies
693
Days of Medication
total across all patients in 2023

About Nortriptyline Hcl: This medication is used to treat mental/mood problems such as depression. Show more ▾

It may help improve mood and feelings of well-being, relieve anxiety and tension, and increase your energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters) in the brain.

In 2023, this provider wrote 17 Medicare prescriptions for Nortriptyline Hcl, about 85% of the volume of the typical Maryland prescriber of this medication (20). Medicare paid an average of $17.02 per fill, versus $17.91 statewide.

How often this provider prescribes it

This provider
17
MD average
20.0

This provider's prescribing volume for this medication is in line with the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$17.02
MD average
$17.91

This provider's average cost per fill is below the MD average for this medication.

25
30-Day Fills
standardized to 30-day supplies
750
Days of Medication
total across all patients in 2023

About Tramadol Hcl: See also Warning section. Show more ▾

This medication is used to help relieve moderate to moderately severe pain. Tramadol belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. A narcotic analgesic proposed for severe pain. It may be habituating.

In 2023, this provider wrote 14 Medicare prescriptions for Tramadol Hcl, about a third of the volume of the typical Maryland prescriber of this medication (45). Medicare paid an average of $25.34 per fill, versus $8.07 statewide.

How often this provider prescribes it

This provider
14
MD average
45.0

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$25.34
MD average
$8.07

Gross Part D cost per fill; not the patient's out-of-pocket price.

14
30-Day Fills
standardized to 30-day supplies
347
Days of Medication
total across all patients in 2023

About Tramadol Hcl-Acetaminophen: See also Warning section. Show more ▾

This product is used to treat moderate to moderately severe pain. It contains 2 medications: tramadol and acetaminophen. Tramadol belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. Acetaminophen is used to relieve pain, and it can also reduce a fever.

In 2023, this provider wrote 14 Medicare prescriptions for Tramadol Hcl-Acetaminophen, about 78% of the volume of the typical Maryland prescriber of this medication (18). Medicare paid an average of $17.63 per fill, versus $22.72 statewide.

How often this provider prescribes it

This provider
14
MD average
18.0

This provider's prescribing volume for this medication is in line with the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$17.63
MD average
$22.72

This provider's average cost per fill is below the MD average for this medication.

14.3
30-Day Fills
standardized to 30-day supplies
347
Days of Medication
total across all patients in 2023

About Diflunisal: Diflunisal is used to relieve mild to moderate pain from various conditions. Show more ▾

It also reduces pain, swelling, and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.

In 2023, this provider wrote 13 Medicare prescriptions for Diflunisal, about the same volume as the typical Maryland prescriber of this medication (13). Medicare paid an average of $73.84 per fill, versus $76.11 statewide.

How often this provider prescribes it

This provider
13
MD average
13.0

This provider's prescribing volume for this medication is in line with the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$73.84
MD average
$76.11

This provider's average cost per fill is below the MD average for this medication.

25
30-Day Fills
standardized to 30-day supplies
750
Days of Medication
total across all patients in 2023

About Sodium Chloride: This product is used to treat dryness inside the nose (nasal passages). Show more ▾

It helps add moisture inside the nose to dissolve and soften thick or crusty mucus. In babies and young children with stuffy noses who cannot blow their noses, using this product helps to make the mucus easier to remove with a nasal bulb syringe. This helps relieve stuffiness and makes breathing easier. This product contains a purified gentle salt solution (also called saline or sodium chloride solution). It does not contain any medication. Hypertonic sodium chloride solution. A solution having an osmotic pressure greater than that of physiologic salt solution (0.9 g NaCl in 100 ml purified water).

In 2023, this provider wrote 13 Medicare prescriptions for Sodium Chloride, about 72% of the volume of the typical Maryland prescriber of this medication (18). Medicare paid an average of $5.57 per fill, versus $22.79 statewide.

How often this provider prescribes it

This provider
13
MD average
18.0

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$5.57
MD average
$22.79

This provider's average cost per fill is below the MD average for this medication.

13
30-Day Fills
standardized to 30-day supplies
273
Days of Medication
total across all patients in 2023

About Hydromorphone Hcl: This medication is used to help relieve moderate to severe pain. Show more ▾

Hydromorphone belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. An opioid analgesic made from MORPHINE and used mainly as an analgesic. It has a shorter duration of action than morphine.

In 2023, this provider wrote 12 Medicare prescriptions for Hydromorphone Hcl, about a third of the volume of the typical Maryland prescriber of this medication (33). Medicare paid an average of $36.34 per fill, versus $22.53 statewide.

How often this provider prescribes it

This provider
12
MD average
33.0

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$36.34
MD average
$22.53

Gross Part D cost per fill; not the patient's out-of-pocket price.

12
30-Day Fills
standardized to 30-day supplies
303
Days of Medication
total across all patients in 2023

About Tramadol Hcl Er: See also Warning section. Show more ▾

This medication is used to help relieve severe ongoing pain. Tramadol belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. A narcotic analgesic proposed for severe pain. It may be habituating.

In 2023, this provider wrote 12 Medicare prescriptions for Tramadol Hcl Er, about half the volume of the typical Maryland prescriber of this medication (25). Medicare paid an average of $72.04 per fill, versus $91.55 statewide.

How often this provider prescribes it

This provider
12
MD average
25.0

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$72.04
MD average
$91.55

This provider's average cost per fill is below the MD average for this medication.

12
30-Day Fills
standardized to 30-day supplies
360
Days of Medication
total across all patients in 2023

About Duloxetine Hcl: Duloxetine is used to treat depression and anxiety. Show more ▾

In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain. A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.

In 2023, this provider wrote 11 Medicare prescriptions for Duloxetine Hcl, about a third of the volume of the typical Maryland prescriber of this medication (37). Medicare paid an average of $39.72 per fill, versus $53.06 statewide.

How often this provider prescribes it

This provider
11
MD average
37.0

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$39.72
MD average
$53.06

This provider's average cost per fill is below the MD average for this medication.

13
30-Day Fills
standardized to 30-day supplies
390
Days of Medication
total across all patients in 2023

About Pregabalin: This medication is used to treat pain caused by nerve damage due to diabetes, shingles (herpes zoster) infection, or spinal cord injury. Show more ▾

This medication is also used to treat pain in people with fibromyalgia. It is also used with other medications to treat certain types of seizures (focal seizures). A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.

In 2023, this provider wrote 11 Medicare prescriptions for Pregabalin, about a third of the volume of the typical Maryland prescriber of this medication (38). Medicare paid an average of $6.39 per fill, versus $57.87 statewide.

How often this provider prescribes it

This provider
11
MD average
38.0

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$6.39
MD average
$57.87

This provider's average cost per fill is below the MD average for this medication.

15
30-Day Fills
standardized to 30-day supplies
450
Days of Medication
total across all patients in 2023
No medications match the current filters.
= the 5 medications this provider prescribes most. More than typical Typical Less than typical= prescription volume vs the average MD prescriber of the same medication; volume reflects practice size as well as clinical preference.Green cost= below the MD average cost per fill.

About this data. The prescription history for MICHAEL JAMES POLYDEFKIS M.D. is compiled from the Centers for Medicare & Medicaid Services (CMS) Medicare Part D Prescriber Public Use File for calendar year 2023, the most recent federal release. Figures cover prescriptions filled for Medicare Part D beneficiaries only; prescriptions under private insurance, Medicaid, or self-pay plans are not included. Because prescribing decisions are generally consistent across coverage types, this record offers a useful view of the overall Neurology prescribing approach at this Baltimore, MD practice.

Reading the costs. Drug costs are gross amounts paid to pharmacies under Part D, including both plan and beneficiary payments. They are not the price a patient pays at the pharmacy counter. Medications with fewer than 11 claims are excluded from the federal source data, and state comparisons use the average volume among MD prescribers of the same medication. Always confirm current medications and costs directly with the provider and your plan.