MICHAEL JAMES POLYDEFKIS M.D.
Prescription History 1194768614
Psychiatry & Neurology - Neurology in Baltimore, MD

Active since June 13, 2006PECOS Enrolled
74.39/100
CMS Quality Rating
600 N WOLFE ST, BALTIMORE, MD 21287(410) 955-9441 Get Directions

NPPES record last updated: January 16, 2026. Verified against the NPPES registry weekly; last sync: October 18, 2026.

Medicare Part D Prescription History

Explore the verified Medicare Part D prescription history, volume metrics, and calculated drug costs for MICHAEL JAMES POLYDEFKIS M.D., an active Neurology specialist practicing in Baltimore, MD. Our medical registry currently tracks 11 unique pharmaceutical formulations prescribed by this provider, representing an estimated volume of 272 documented patient claims. Among these therapy options, the most frequently utilized medication is Gabapentin, which accounts for 47 claims alone. Use the table below to sort by claims, cost, or utilization compared with the state average; select any medication for its full profile.

11
Medications
272
Total Claims
310
30-Day Fills
Gabapentin
Most Prescribed · 47 claims
View details
11 medications · 2024 Medicare Part D
Medicare Part D medications prescribed by MICHAEL JAMES POLYDEFKIS M.D. in 2024, with prescription volumes, average cost per fill, and MD state comparisons
Medication Prescriptions (2024)Rx (2024) Avg Cost per FillCost / Fill Vs. Other MD PrescribersVs. MD Avg

About Gabapentin: Gabapentin is used with other medications to prevent and control seizures. Show more ▾

It is also used to relieve nerve pain following shingles (a painful rash due to herpes zoster infection) in adults. Gabapentin is known as an anticonvulsant or antiepileptic drug. A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.

In 2024, this provider wrote 47 Medicare prescriptions for Gabapentin, about 67% of the volume of the typical Maryland prescriber of this medication (70.6). Medicare paid an average of $33.08 per fill, versus $15.67 statewide.

How often this provider prescribes it

This provider
47
MD average
70.6

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$33.08
MD average
$15.67

Gross Part D cost per fill; not the patient's out-of-pocket price.

73.5
30-Day Fills
standardized to 30-day supplies
2,205
Days of Medication
total across all patients in 2024

About Fentanyl: This medication is used to help relieve severe ongoing pain (such as due to cancer). Show more ▾

Fentanyl belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. Do not use the patch form of fentanyl to relieve pain that is mild or that will go away in a few days. This medication is not for occasional ("as needed") use. A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)

In 2024, this provider wrote 41 Medicare prescriptions for Fentanyl, about 1.3 times the volume of the typical Maryland prescriber of this medication (31.8). Medicare paid an average of $225.20 per fill, versus $109.37 statewide.

How often this provider prescribes it

This provider
41
MD average
31.8

This provider prescribes this medication more often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$225.20
MD average
$109.37

Gross Part D cost per fill; not the patient's out-of-pocket price.

41
30-Day Fills
standardized to 30-day supplies
1,196
Days of Medication
total across all patients in 2024

About Privigen: This medication is used to strengthen the body's natural defense system (immune system) to lower the risk of infection in persons with a weakened immune system. Show more ▾

This medication is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenia purpura-ITP). Platelets are needed to stop bleeding and form blood clots. Some immune globulin products may also be used to treat certain types of muscle weakness problem (multifocal motor neuropathy, dermatomyositis) or a certain nerve disorder (chronic inflammatory demyelinating polyneuropathy-CIDP). Some products may also be used to prevent certain blood vessel disorders in people with Kawasaki syndrome. Immunoglobulin preparations used in intravenous infusion, containing primarily IMMUNOGLOBULIN G. They are used to treat a variety of diseases associated with decreased or abnormal immunoglobulin levels including pediatric AIDS; primary HYPERGAMMAGLOBULINEMIA; SCID; CYTOMEGALOVIRUS infections in transplant recipients, LYMPHOCYTIC LEUKEMIA, CHRONIC; Kawasaki syndrome, infection in neonates, and IDIOPATHIC THROMBOCYTOPENIC PURPURA.

In 2024, this provider wrote 34 Medicare prescriptions for Privigen, about 1.3 times the volume of the typical Maryland prescriber of this medication (26). Medicare paid an average of $8,400.76 per fill, versus $12,574.52 statewide.

How often this provider prescribes it

This provider
34
MD average
26.0

This provider prescribes this medication more often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$8,400.76
MD average
$12,574.52

This provider's average cost per fill is below the MD average for this medication.

34
30-Day Fills
standardized to 30-day supplies
714
Days of Medication
total across all patients in 2024

About Onpattro: This medication is used to treat nerve problems due to a certain inherited condition (transthyretin-mediated amyloidosis). Show more ▾

This condition causes a protein that your body normally makes (transthyretin-TTR), to change shape and build up in different parts of your body, which can affect the nerves, heart, and stomach/intestines. This medication works by decreasing the buildup of TTR in your body. Small interfering RNA encapsulated within lipid nanoparticles for treatment of familial amyloidotic polyneuropathy.

In 2024, this provider wrote 33 Medicare prescriptions for Onpattro. Medicare paid an average of $30,214.95 per fill. No state comparison is available for this medication.

How often this provider prescribes it

No state benchmark is available for this medication.

What Medicare paid per fill

$30,214.95
Cost per fill

Gross Part D cost per fill; not the patient's out-of-pocket price.

33
30-Day Fills
standardized to 30-day supplies
693
Days of Medication
total across all patients in 2024

About Nortriptyline Hcl: This medication is used to treat depression. Show more ▾

Nortriptyline belongs to a class of drugs known as tricyclic antidepressants. It works by helping to restore the balance of certain natural substances in the brain. A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.

In 2024, this provider wrote 31 Medicare prescriptions for Nortriptyline Hcl, about 1.5 times the volume of the typical Maryland prescriber of this medication (21.4). Medicare paid an average of $4.56 per fill, versus $15.58 statewide.

How often this provider prescribes it

This provider
31
MD average
21.4

This provider prescribes this medication more often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$4.56
MD average
$15.58

This provider's average cost per fill is below the MD average for this medication.

35
30-Day Fills
standardized to 30-day supplies
1,050
Days of Medication
total across all patients in 2024

About Tramadol Hcl: See also Warning section. Show more ▾

This medication is used to help relieve moderate to moderately severe pain. Tramadol belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. A narcotic analgesic proposed for severe pain. It may be habituating.

In 2024, this provider wrote 17 Medicare prescriptions for Tramadol Hcl, about a third of the volume of the typical Maryland prescriber of this medication (46.3). Medicare paid an average of $21.79 per fill, versus $7.26 statewide.

How often this provider prescribes it

This provider
17
MD average
46.3

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$21.79
MD average
$7.26

Gross Part D cost per fill; not the patient's out-of-pocket price.

17
30-Day Fills
standardized to 30-day supplies
345
Days of Medication
total across all patients in 2024

About Gamunex-C: This medication is used in people with a certain type of weakened immune system (primary immune deficiency) to strengthen it and to lower the risk of infection. Show more ▾

This medication is made from human blood that has a high level of antibodies which help fight infections. This product is also used to increase the number of certain blood cells (platelets) in people with a certain blood disorder (idiopathic thrombocytopenic purpura-ITP). Platelets are needed to stop bleeding and to form normal blood clots. In addition, this medication is used to treat a certain nerve disorder (chronic inflammatory demyelinating polyneuropathy-CIDP). This disorder causes weakness and numbness/tingling/pain in the arms and legs. This medication helps to improve these symptoms and prevents relapse.

In 2024, this provider wrote 16 Medicare prescriptions for Gamunex-C, about 64% of the volume of the typical Maryland prescriber of this medication (24.8). Medicare paid an average of $8,837.21 per fill, versus $9,857.56 statewide.

How often this provider prescribes it

This provider
16
MD average
24.8

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$8,837.21
MD average
$9,857.56

This provider's average cost per fill is below the MD average for this medication.

16
30-Day Fills
standardized to 30-day supplies
360
Days of Medication
total across all patients in 2024

About Duloxetine Hcl: This medication is used to treat certain mental/mood disorders (such as depression, anxiety). Show more ▾

It is also used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain. A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.

In 2024, this provider wrote 15 Medicare prescriptions for Duloxetine Hcl, about a third of the volume of the typical Maryland prescriber of this medication (39.8). Medicare paid an average of $17.39 per fill, versus $28.92 statewide.

How often this provider prescribes it

This provider
15
MD average
39.8

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$17.39
MD average
$28.92

This provider's average cost per fill is below the MD average for this medication.

19
30-Day Fills
standardized to 30-day supplies
570
Days of Medication
total across all patients in 2024

About Diflunisal: Diflunisal is used to relieve mild to moderate pain from various conditions. Show more ▾

It also reduces pain, swelling, and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). This medication is not recommended for use in children under 12 years of age. A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.

In 2024, this provider wrote 13 Medicare prescriptions for Diflunisal. Medicare paid an average of $55.32 per fill. No state comparison is available for this medication.

How often this provider prescribes it

No state benchmark is available for this medication.

What Medicare paid per fill

$55.32
Cost per fill

Gross Part D cost per fill; not the patient's out-of-pocket price.

16.5
30-Day Fills
standardized to 30-day supplies
495
Days of Medication
total across all patients in 2024

About Methylprednisolone Sodium Succ: This medication is used to treat conditions such as arthritis, blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/kidney/intestinal/lung diseases, and immune system disorders. Show more ▾

It decreases your immune system's response to various diseases to reduce symptoms such as swelling, pain, and allergic-type reactions. Methylprednisolone is a corticosteroid hormone. This injectable form of methylprednisolone is used when a similar drug cannot be taken by mouth or when a very fast response is needed, especially in patients with severe medical conditions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone may also be used with other medications in hormone disorders.

In 2024, this provider wrote 13 Medicare prescriptions for Methylprednisolone Sodium Succ. Medicare paid an average of $25.32 per fill. No state comparison is available for this medication.

How often this provider prescribes it

No state benchmark is available for this medication.

What Medicare paid per fill

$25.32
Cost per fill

Gross Part D cost per fill; not the patient's out-of-pocket price.

13
30-Day Fills
standardized to 30-day supplies
233
Days of Medication
total across all patients in 2024

About Tramadol Hcl Er: See also Warning section. Show more ▾

This medication is used to help relieve severe ongoing pain. Tramadol belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. A narcotic analgesic proposed for severe pain. It may be habituating.

In 2024, this provider wrote 12 Medicare prescriptions for Tramadol Hcl Er, about half the volume of the typical Maryland prescriber of this medication (26.9). Medicare paid an average of $73.65 per fill, versus $64.21 statewide.

How often this provider prescribes it

This provider
12
MD average
26.9

This provider prescribes this medication less often than the average MD prescriber. Utilization reflects practice size as well as clinical preference.

What Medicare paid per fill

This provider
$73.65
MD average
$64.21

Gross Part D cost per fill; not the patient's out-of-pocket price.

12
30-Day Fills
standardized to 30-day supplies
360
Days of Medication
total across all patients in 2024
No medications match the current filters.
= the 5 medications this provider prescribes most.▲ More than typical≈ Typical▼ Less than typical= prescription volume vs the average MD prescriber of the same medication; volume reflects practice size as well as clinical preference.Green cost= below the MD average cost per fill.

About this data. The prescription history for MICHAEL JAMES POLYDEFKIS M.D. is compiled from the Centers for Medicare & Medicaid Services (CMS) Medicare Part D Prescriber Public Use File for calendar year 2024, the most recent federal release. Figures cover prescriptions filled for Medicare Part D beneficiaries only; prescriptions under private insurance, Medicaid, or self-pay plans are not included. Because prescribing decisions are generally consistent across coverage types, this record offers a useful view of the overall Neurology prescribing approach at this Baltimore, MD practice.

Reading the costs. Drug costs are gross amounts paid to pharmacies under Part D, including both plan and beneficiary payments. They are not the price a patient pays at the pharmacy counter. Medications with fewer than 11 claims are excluded from the federal source data, and state comparisons use the average among MD prescribers of the same medication and form, shown only when at least five prescribers contribute. Always confirm current medications and costs directly with the provider and your plan.

About the medication summaries. Drug use descriptions come from the CMS Medicare Part D Drug Spending Dashboard (2024), and substance definitions from Medical Subject Headings (MeSH) 2026, U.S. National Library of Medicine. They are summaries that do not contain all possible information about a medication and are not individual medical advice. Ask a health care professional about any medication and your specific health needs.