MRS. CYRENA NERISSA MUFFLEY FNP
NPI 1164983060
Nurse Practitioner - Family in Biloxi, MS
About Mrs. Cyrena Nerissa Muffley Fnp NPPES
Official registry information on file with the National Plan and Provider Enumeration System.
MRS. CYRENA NERISSA MUFFLEY FNP (NPI 1164983060) is an individual family provider in Biloxi, Mississippi, licensed in Mississippi (903431) and active in the NPI registry since March 2019. She is enrolled in Medicare PECOS and maintains a secondary practice location in Moss Point.
NPPES Registry Identity
Specialties & Licenses
Secondary Practice Location 1
Other Identifiers 1
Medicare Participation & PECOS CMS
Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.
Medicare Enrollment Status
Enrolled in Medicare (PECOS)
Mrs. Cyrena Nerissa Muffley Fnp is registered in the CMS Provider Enrollment, Chain and Ownership System (PECOS).
Medicare Billing Reassignments
5Medicare enrollment records show Cyrena Muffley reassigns Medicare billing to 5 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.
Biloxi, MS 39531
- Reassigned Medicare billing, Mississippi enrollment
- 7 clinicians in this Medicare group
Gulfport, MS 39503
- Reassigned Medicare billing, Mississippi enrollment
- 298 clinicians in this Medicare group
Ocean Springs, MS 39564
- Reassigned Medicare billing, Mississippi enrollment
- 450 clinicians in this Medicare group
Port Arthur, TX 77640
- Reassigned Medicare billing, Texas enrollment
- 157 clinicians in this Medicare group
Miami, FL 33126
- Reassigned Medicare billing, Texas enrollment
- 21 clinicians in this Medicare group
Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.
Physician Visit Costs CMS claims · ZIP area
Typical Medicare office-visit costs in the 39531 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.
Other Providers at the Same Location NPPES 9
Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.
BILOXI, MS 39531
Frequently Asked Questions NPPES & CMS
Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.
What is Cyrena Muffley's NPI number?
The NPI number for Cyrena Muffley is 1164983060. It was assigned to this individual provider in the NPPES registry on March 25, 2019.
Where is Cyrena Muffley located?
Cyrena Muffley practices at 2650 Beach Blvd Ste 40, Biloxi, MS 39531. The listed phone number is (228) 273-4611.
What is Cyrena Muffley's specialty?
The primary specialty registered for this NPI is Nurse Practitioner, specializing in Family, with taxonomy code 363LF0000X.
Is Cyrena Muffley enrolled in Medicare?
Yes. Cyrena Muffley is registered in the Medicare PECOS enrollment system.
Which organizations bill Medicare for Cyrena Muffley's services?
According to the CMS Revalidation Reassignment List (October 2026 release), Cyrena Muffley reassigns Medicare benefits to 5 organizations: Centerwell Senior Primary Care Ms Cs PC (Biloxi, MS), Singing River Gulfport (Gulfport, MS), Singing River Health System (Ocean Springs, MS), Centerwell Senior Primary Care (tx) PA (Port Arthur, TX) and Centerwell Senior Primary Care Tx Cs PA (Miami, FL). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Cyrena Muffley's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.
When was this NPI record last updated?
The NPPES record for Cyrena Muffley was last updated on September 17, 2026. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 51 days ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.
# Mrs. Cyrena Nerissa Muffley, FNP · NPI 1164983060
Family physician in Biloxi, Mississippi. Individual provider, active in the CMS NPPES registry since March 25, 2019.
## Identity
- **NPI:** 1164983060 (Entity type: Individual)
- **Enumerated:** March 25, 2019
- **Primary specialty:** Nurse Practitioner - Family · taxonomy 363LF0000X
- **State license:** 903431 (Mississippi)
- **Sole proprietor:** Yes
## Practice location
- **Address:** 2650 BEACH BLVD STE 40, Biloxi, MS 39531-4517
- **Phone:** (228) 273-4611
## Medicare
- **Medicare:** Enrolled in Medicare (PECOS)
- **Ordering & referring:** eligible for Part B labs & imaging, durable medical equipment, home health, power mobility devices
- **Bills Medicare through:** 5 organizations under Medicare reassignment (form CMS-855R): Centerwell Senior Primary Care Ms Cs PC (NPI 1730980434, Biloxi, MS); Singing River Gulfport (NPI 1861010159, Gulfport, MS); Singing River Health System (NPI 1053528109, Ocean Springs, MS); Centerwell Senior Primary Care (tx) PA (NPI 1568094282, Port Arthur, TX); Centerwell Senior Primary Care Tx Cs PA (NPI 1659172112, Miami, FL) · CMS Revalidation Reassignment List, October 2026 release
## Record status
- **NPPES last updated:** September 17, 2026
- **Other identifiers:** Medicaid 01451001 (MS)
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Source: [NPI Profile](https://npiprofile.com/npi/1164983060) · Data from the CMS NPPES public registry.