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DR. CHARLES L KNUPP MD
NPI 1154313575
Internal Medicine - Hematology & Oncology in Greenville, NC

Active since August 22, 2005PECOS EnrolledAccepts Medicare Assignment
98.33/100
CMS Quality Rating
600 MOYE BLVD, ECU PHYSICIANS LEO JENKINS CANCER CENTER, GREENVILLE, NC 27834(252) 744-1888(252) 744-7005 Get Directions Write a Review

NPPES record last updated: November 8, 2011. Verified against the NPPES registry weekly; last sync: October 25, 2026.

About Dr. Charles L Knupp Md NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

DR. CHARLES L KNUPP MD (NPI 1154313575) is an individual hematology & oncology provider in Greenville, North Carolina, licensed in North Carolina (24433) and active in the NPI registry since August 2005. He is enrolled in Medicare PECOS, is affiliated with Ecu Health Medical Center, and is a graduate of University Of Maryland School Of Medicine (1976).

NPPES Registry Identity

NPI1154313575
Entity TypeIndividualMale
Primary Taxonomy207RH0003X
Provider Legal NameDR. CHARLES L KNUPPCredential: MD
Location Address600 MOYE BLVD, ECU PHYSICIANS LEO JENKINS CANCER CENTERGreenville, NC 27834-4300
Mailing AddressPo Box 751069, Ecu PhysiciansCharlotte, NC 28275-1069
Phone(252) 744-1888
Fax(252) 744-7005
Sole ProprietorNo
Medical School CMSUniversity Of Maryland School Of MedicineGraduated 1976
Enumeration DateAugust 22, 2005
Last NPPES UpdateNovember 8, 2011
✔ NPI 1154313575 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyInternal Medicine · Hematology & OncologyAllopathic & Osteopathic Physicians
Taxonomy Code207RH0003X
License✔ Licensed in NC · 24433
Definition
An internist doctor of osteopathy that specializes in the treatment of the combination of hematology and oncology disorders. A doctor of osteopathy that is board eligible/certified by the American Osteopathic Board of Internal Medicine WAS able to obtain a Certificate of Special Qualifications in the field of Hematology and Oncology. The Certificate is NO longer offered.
600 MOYE BLVD, Greenville, NC 27834
Open in Google Maps ↗

Other Identifiers 6

Other830002853NC · Railroad Medicare
Medicare PIN207935ANC
Medicare PIN207935HNC
Other49908NC · Bcbs Nc
Medicare UPINC84963NC
Medicaid8949908NC

Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Blue Cross and Blue Shield of NC.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Dr. Charles L Knupp Md is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID1557449261
PECOS Enrollment IDI20080422000302
Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

3

Medicare enrollment records show Charles Knupp reassigns Medicare billing to 3 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

East Carolina University
0.1 mi
General Practice
600 MOYE BLVD
Greenville, NC 27834
  • Reassigned Medicare billing, North Carolina enrollment
  • 930 clinicians in this Medicare group
NPI 1689815284 (252) 744-4618
Vidant Medical Group LLC
0.3 mi
Multi-Specialty
2100 STANTONSBURG RD
Greenville, NC 27834
  • Reassigned Medicare billing, North Carolina enrollment
  • 1,653 clinicians in this Medicare group
NPI 1477648731 (252) 847-2181
Outerbanks Professional Services LLC
99 mi
Family Medicine
604 AMANDA ST
Manteo, NC 27954
  • Reassigned Medicare billing, North Carolina enrollment
  • Medicare enrollment name: Outer Banks Professional Services, LLC
  • 346 clinicians in this Medicare group
NPI 1457686891 (252) 473-3478

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Areas of Expertise CMS Part B claims 5

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214
This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.
163 services81 patients
Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes 99232
Follow-up hospital inpatient care involves daily check-ups while you're admitted in the hospital. Typically, a healthcare provider spends about 25 minutes each day reviewing your condition, adjusting treatment if needed, and answering any questions you might have.
127 services42 patients
Initial hospital care with straightforward or low-level medical decision making, if using time, at least 55 minutes 99222
Initial hospital inpatient care is a service where a healthcare provider spends about 50 minutes per day overseeing your care while you're admitted in the hospital. This includes reviewing your health status, planning your treatment, and ensuring your safety and comfort.
76 services68 patients
New patient office or other outpatient visit with moderate level of medical decision making, if using time, 45 minutes or more 99204
This is a first-time office or outpatient visit lasting between 45-59 minutes. The healthcare provider evaluates your health, discusses your medical history, and may suggest further tests or treatments. It's an opportunity to ask questions and understand your health better.
19 services19 patients
Established patient office or other outpatient visit with low level od decision making, if using time, 20 minutes or more 99213
This is a routine visit for patients who have already been seen by the healthcare provider. During this approximately 20-29 minute appointment, your health status will be evaluated and any necessary treatments or tests will be discussed. It's a chance to address any health concerns you may have.
12 services11 patients

Hospital Affiliations CMS Care Compare

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Ecu Health Medical Center

Acute Care Hospitals · Greenville, NC
2/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number340040
Location2100 Stantonsburg RdGreenville, NC 27834 · Pitt County
Emergency services Birthing friendly

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 27834 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient
$165.09 typical visit price
range $54.12 – $165.09
Typical copayment $41.27 (range $13.53 – $41.27)
Most-billed visit code 99205
Established Patient
$95.94 typical visit price
range $17.21 – $134.61
Typical copayment $23.98 (range $4.30 – $33.65)
Most-billed visit code 99214
Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Medicare Quality Performance CMS QPP · MIPS

Performance in the CMS Quality Payment Program: the MIPS final score across four weighted categories, and the individual quality measures reported to Medicare.

98.33/100
MIPS Final ScoreMerit-based Incentive Payment System · CMS Quality Payment Program
Scored through an Alternative Payment Model
Quality82.93
Promoting Interoperability100
Improvement Activities40

Other Providers at the Same Location NPPES 20

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

MS. MONICA HOUGH CCC-SLP
Speech-Language Pathologist
600 MOYE BLVD, SCHOOL OF ALLIED HEALTH SCIENCES/CSDI
GREENVILLE, NC 27834
Pitt County (252) 744-6099
EAST CAROLINA UNIVERSITY
Pathology (Anatomic Pathology & Clinical Pathology)
600 MOYE BLVD
GREENVILLE, NC 27834
Pitt County (252) 744-2128
DR. EDWARD L TREADWELL M.D.
Internal Medicine (Rheumatology)
600 MOYE BLVD
GREENVILLE, NC 27834
Pitt County (252) 744-3169
DR. JUDY W WOOD MD
Pediatrics
600 MOYE BLVD, PEDIATRIC OUTPATIENT CENTER
GREENVILLE, NC 27834
Pitt County (252) 744-2335
DR. PAUL R WALKER M.D.
Internal Medicine (Hematology & Oncology)
600 MOYE BLVD, LEO JENKINS CANCER SERVICES HEMTOLOGY/ONCOLOGY
GREENVILLE, NC 27834
Pitt County (252) 744-3563
DR. MICHAEL W.A. CHU M.D.
Surgery
600 MOYE BLVD, LEO JENKINS CANCER CENTER
GREENVILLE, NC 27834
Pitt County (252) 744-4822
DR. JOHN D CHRISTIE MD, PHD
Pathology (Anatomic Pathology & Clinical Pathology)
600 MOYE BLVD, ECU PHYSICIANS PATHOLOGY BRODY OUTPATIENT CENTER
GREENVILLE, NC 27834
Pitt County (252) 744-2803
MRS. ALLYSON HILL TURNAGE MS. CCC-SLP
Speech-Language Pathologist
600 MOYE BLVD
GREENVILLE, NC 27834
Pitt County (252) 744-6104

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Charles Knupp's NPI number?

The NPI number for Charles Knupp is 1154313575. It was assigned to this individual provider in the NPPES registry on August 22, 2005.

Where is Charles Knupp located?

Charles Knupp practices at 600 Moye Blvd Ecu Physicians Leo Jenkins Cancer Center, Greenville, NC 27834. The listed phone number is (252) 744-1888.

What is Charles Knupp's specialty?

The primary specialty registered for this NPI is Internal Medicine, specializing in Hematology & Oncology, with taxonomy code 207RH0003X.

Is Charles Knupp enrolled in Medicare?

Yes. Charles Knupp is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

Which organizations bill Medicare for Charles Knupp's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Charles Knupp reassigns Medicare benefits to 3 organizations: East Carolina University (Greenville, NC), Vidant Medical Group LLC (Greenville, NC) and Outerbanks Professional Services LLC (Manteo, NC). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Charles Knupp's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

What insurance does Charles Knupp accept?

Health plans from Blue Cross and Blue Shield of NC list Charles Knupp as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Charles Knupp affiliated with any hospitals?

According to CMS data, Charles Knupp is affiliated with Ecu Health Medical Center.

When was this NPI record last updated?

The NPPES record for Charles Knupp was last updated on November 8, 2011. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 14 years ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.