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MRS. REGINA F. HOLMES APRN
NPI 1124347604
Nurse Practitioner - Family in Loris, SC

Active since May 24, 2010PECOS EnrolledAccepts Medicare Assignment
AGAPE SENIOR PRIMARY CARE INC DBA MAIN STREET PHYSICIAN, 3612 MITCHELL STREET, LORIS, SC 29569(843) 756-2122(843) 756-2121 Get Directions Write a Review

NPPES record last updated: December 6, 2018. Verified against the NPPES registry weekly; last sync: November 01, 2026.

About Mrs. Regina F. Holmes Aprn NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

MRS. REGINA F. HOLMES APRN (NPI 1124347604) is an individual family provider in Loris, South Carolina, licensed in South Carolina (F4220) and active in the NPI registry since May 2010. She is enrolled in Medicare PECOS, is affiliated with Mcleod Loris Hospital, and is a graduate of Other (2001).

NPPES Registry Identity

NPI1124347604
Entity TypeIndividualFemale
Primary Taxonomy363LF0000X
Provider Legal NameMRS. REGINA F. HOLMESCredential: APRN
Location AddressAGAPE SENIOR PRIMARY CARE INC DBA MAIN STREET PHYSICIAN, 3612 MITCHELL STREETLoris, SC 29569
Mailing Address1053 Center Street, Attention: Credentialing DepartmentWest Columbia, SC 29169 · (800) 726-2350 · Fax (843) 716-7195
Phone(843) 756-2122
Fax(843) 756-2121
Sole ProprietorYes
Medical School CMSOtherGraduated 2001
Enumeration DateMay 24, 2010
Last NPPES UpdateDecember 6, 2018
✔ NPI 1124347604 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyNurse Practitioner · FamilyPhysician Assistants & Advanced Practice Nursing Providers
Taxonomy Code363LF0000X
License✔ Licensed in SC · F4220
AGAPE SENIOR PRIMARY CARE INC DBA MAIN STREET PHYSICIAN, Loris, SC 29569
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Other Identifiers 1

MedicaidNP1730SC

Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include BlueCross BlueShield of South Carolina, First Choice Next, InStil Health.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, billing reassignment, and ordering and referring status from CMS.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Mrs. Regina F. Holmes Aprn is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID8628263126
PECOS Enrollment IDI20101110000439
Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Medicare Billing Reassignments

3

Medicare enrollment records show Regina Holmes reassigns Medicare billing to 3 organizations. Each organization bills Medicare for the services this provider delivers there; the nearest is listed first.

Mcleod Loris Seacoast Hospital
5.6 mi
Nurse Anesthetist, Certified Registered
3655 MITCHELL ST
Loris, SC 29569
  • Reassigned Medicare billing, South Carolina enrollment
  • 240 clinicians in this Medicare group
NPI 1265708119 (843) 716-7000
Mcleod Physician Associates II
50 mi
Urology
800 E CHEVES ST, SUITE 350
Florence, SC 29506
  • Reassigned Medicare billing, South Carolina enrollment
  • 878 clinicians in this Medicare group
NPI 1649428194 (843) 665-2000
Sc House Calls Inc
122 mi
Family Medicine
111 DOCTOR CIR
Columbia, SC 29203
  • Reassigned Medicare billing, South Carolina enrollment
  • 631 clinicians in this Medicare group
NPI 1518048859 (800) 491-0909

Source: CMS Revalidation Reassignment List, October 2026 release. Reassignment records can lag staffing changes; confirm a current affiliation with the organization.

Areas of Expertise CMS Part B claims 2

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Initial hospital care with moderate level of medical decision making, if using time, at least 75 minutes 99223
Initial hospital inpatient care per day, typically 70 minutes, refers to the daily medical service provided to patients admitted to the hospital. This includes a comprehensive evaluation, diagnosis, treatment plan, and monitoring of your health condition. It ensures your well-being during your hospital stay.
44 services44 patients
Initial hospital care with straightforward or low-level medical decision making, if using time, at least 55 minutes 99222
Initial hospital inpatient care is a service where a healthcare provider spends about 50 minutes per day overseeing your care while you're admitted in the hospital. This includes reviewing your health status, planning your treatment, and ensuring your safety and comfort.
11 services11 patients

Hospital Affiliations CMS Care Compare

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Mcleod Loris Hospital

Acute Care Hospitals · Loris, SC
3/5 CMS rating
OwnershipVoluntary non-profit - Private
CMS Certification Number420105
Location3655 Mitchell StreetLoris, SC 29569 · Horry County

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 29569 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient
$83.18 typical visit price
range $53.57 – $163.84
Typical copayment $20.79 (range $13.39 – $40.96)
Most-billed visit code 99203
Established Patient
$95.12 typical visit price
range $16.96 – $133.52
Typical copayment $23.78 (range $4.24 – $33.38)
Most-billed visit code 99214
Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Medicare Quality Performance CMS QPP · MIPS

Performance in the CMS Quality Payment Program: the MIPS final score across four weighted categories, and the individual quality measures reported to Medicare.

Reported Quality Measures

e-Prescribing
At least one permissible prescription written by the MIPS eligible clinician is queried for a drug formulary and transmitted electronically using certified EHR technology.
93%581 patients4/55-star benchmark: 99%
Medication Reconciliation
The MIPS eligible clinician performs medication reconciliation for at least one transition of care in which the patient is transitioned into the care of the MIPS eligible clinician.
97%39 patients4/55-star benchmark: 100%
Patient-Specific Education
The MIPS eligible clinician must use clinically relevant information from CEHRT to identify patient-specific educational resources and provide access to those materials to at least one unique patient seen by the MIPS eligible clinician.
90%310 patients4/55-star benchmark: 97%
Provide Patient Access
At least one patient seen by the MIPS eligible clinician during the performance period is provided timely access to view online, download, and transmit to a third party their health information subject to the MIPS eligible clinician's discretion to withhold…
11%310 patients1/55-star benchmark: 100%
Providers report different measures because they deliver different services; reporting more or less information is not a reflection of quality. Star ratings appear only where CMS assigned them.

Frequently Asked Questions NPPES & CMS

Common questions about this NPI record, answered from the official NPPES registry and CMS datasets shown on this page.

What is Regina Holmes's NPI number?

The NPI number for Regina Holmes is 1124347604. It was assigned to this individual provider in the NPPES registry on May 24, 2010.

Where is Regina Holmes located?

Regina Holmes practices at Agape Senior Primary Care Inc Dba Main Street Physician 3612 Mitchell Street, Loris, SC 29569. The listed phone number is (843) 756-2122.

What is Regina Holmes's specialty?

The primary specialty registered for this NPI is Nurse Practitioner, specializing in Family, with taxonomy code 363LF0000X.

Is Regina Holmes enrolled in Medicare?

Yes. Regina Holmes is registered in the Medicare PECOS system and accepts Medicare assignment, which means accepting the Medicare-approved amount as payment in full for covered services.

Which organizations bill Medicare for Regina Holmes's services?

According to the CMS Revalidation Reassignment List (October 2026 release), Regina Holmes reassigns Medicare benefits to 3 organizations: Mcleod Loris Seacoast Hospital (Loris, SC), Mcleod Physician Associates II (Florence, SC) and Sc House Calls Inc (Columbia, SC). Each reassignment is filed with Medicare on form CMS-855R, signed by both the clinician and the organization, and lets the organization bill Medicare and receive payment for Regina Holmes's services. Reassignment records can lag staffing changes; confirm current arrangements with the organization.

What insurance does Regina Holmes accept?

Health plans from BlueCross BlueShield of South Carolina, First Choice Next and InStil Health list Regina Holmes as in-network in at least one marketplace plan. Coverage varies by plan and year; verify with the insurer or the provider before a visit.

Is Regina Holmes affiliated with any hospitals?

According to CMS data, Regina Holmes is affiliated with Mcleod Loris Hospital.

When was this NPI record last updated?

The NPPES record for Regina Holmes was last updated on December 6, 2018. NPI Profile syncs weekly with the NPPES registry data releases published by CMS. This NPI record was last updated 7 years ago. If this record has changed at CMS more recently, you can request an on-demand re-check against the live CMS registry, directly from this page.