CHRISTINE GAIL SIMONE M.D.
NPI 1649591660
Internal Medicine - Hematology & Oncology in Stuart, FL

Q: What is Christine Simone's NPI number?

The NPI number for Christine Simone is 1649591660. It was assigned to this individual provider in the NPPES registry on June 14, 2010.

Q: What is Christine Simone's specialty?

The primary specialty registered for this NPI is Internal Medicine, specializing in Hematology & Oncology, with taxonomy code 207RH0003X.

Q: When was this NPI record last updated?

The NPPES record for Christine Simone was last updated on October 18, 2025. NPI Profile syncs with the weekly NPPES data releases published by CMS.

Active since June 14, 2010PECOS EnrolledAccepts Medicare Assignment

89.89/100

CMS Quality Rating

448 SE OSCEOLA ST, STUART, FL 34994(772) 276-7242 Get Directions Write a Review

NPPES record last updated: October 18, 2025. Verified against the NPPES registry weekly; last sync: July 26, 2026.

Record update history: Nov 1, 2016, Sep 14, 2016, Sep 1, 2016 and 1 more (4 updates tracked since 2016).

On this page

About Christine Gail Simone M.d. NPPES

Official registry information on file with the National Plan and Provider Enumeration System.

CHRISTINE GAIL SIMONE M.D. (NPI 1649591660) is an individual hematology & oncology provider in Stuart, Florida, licensed in Florida (ME113791) and active in the NPI registry since June 2010. She is enrolled in Medicare PECOS, is affiliated with Cleveland Clinic Martin North Hospital, and is a graduate of University Of Florida College Of Medicine (2010).

NPPES Registry Identity

NPI1649591660

Entity TypeIndividualFemale

Primary Taxonomy207RH0003X

Provider Legal NameCHRISTINE GAIL SIMONECredential: M.D.

Location Address448 SE OSCEOLA STStuart, FL 34994-2577

Mailing Address448 Se Osceola StStuart, FL 34994-2577 · (772) 276-7242

Phone(772) 276-7242

Sole ProprietorNo

Medical School CMSUniversity Of Florida College Of MedicineGraduated 2010

Enumeration DateJune 14, 2010

Last NPPES UpdateOctober 18, 20254 updates tracked since enumeration

NPPES CertifiedOctober 18, 2025

✔ NPI 1649591660 is a valid, active identifier and passes the ISO check-digit test.

Specialties & Licenses

★ Primary SpecialtyInternal Medicine · Hematology & OncologyAllopathic & Osteopathic Physicians

Taxonomy Code207RH0003X

License✔ Licensed in FL · ME113791

Definition

An internist doctor of osteopathy that specializes in the treatment of the combination of hematology and oncology disorders. A doctor of osteopathy that is board eligible/certified by the American Osteopathic Board of Internal Medicine WAS able to obtain a Certificate of Special Qualifications in the field of Hematology and Oncology. The Certificate is NO longer offered.

448 SE OSCEOLA ST, Stuart, FL 34994

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Other Identifiers 1

Medicaid018300000FL

Accepted Insurance

The full list of accepted plans is on the Insurance tab. Issuers include Ambetter from Superior HealthPlan, Ambetter Health, Ambetter of Alabama and more.Insurance ›

Medicare Participation & PECOS CMS

Medicare enrollment, assignment, and ordering and referring status from the CMS PECOS system.

Medicare Enrollment Status

✔

Enrolled in Medicare and accepts Medicare assignment

Christine Gail Simone M.d. is registered in PECOS and agrees to accept the Medicare-approved amount as full payment. Medicare patients are not billed beyond the standard deductible and coinsurance.

PECOS PAC ID9739323528

PECOS Enrollment IDI20160803001402

Eligible to Order & Refer✔ Part B Labs & Imaging✔ Durable Medical Equipment✔ Home Health Agency✔ Power Mobility DevicesPer the CMS Ordering and Referring file. Eligibility means Medicare pays claims that this provider orders or refers for these categories.

Areas of Expertise CMS Part B claims 56

Services this provider delivered to Medicare fee-for-service patients, from the CMS Medicare utilization data. Higher counts generally reflect more experience with a service; care delivered outside Medicare is not included.

Injection, ferric carboxymaltose, 1 mg J1439

Ferric carboxymaltose is an iron supplement injection. It's given when your body needs more iron than you can consume through diet, like in anemia. The injection is administered by a healthcare professional into a vein.

54,750 services34 patients

Injection, pembrolizumab, 1 mg J9271

Pembrolizumab is a medication given via injection to help your body's immune system fight certain types of cancer. It's typically administered in a hospital or clinic by a healthcare professional.

21,800 services20 patients

Injection, aprepitant, 1 mg J0185

Aprepitant injection is a medication used to prevent nausea and vomiting caused by chemotherapy. It works by blocking certain substances in the brain that trigger these symptoms. The dosage is based on your medical condition and response to treatment.

13,260 services21 patients

Injection, granisetron, extended-release, 0.1 mg J1627

Granisetron extended-release injection is a medication that helps prevent nausea and vomiting often caused by cancer treatments like chemotherapy. It's administered under the skin and slowly releases the drug over time to provide long-lasting effects.

10,600 services23 patients

Low osmolar contrast material, 300-399 mg/ml iodine concentration, per ml Q9967

Low osmolar contrast material with 300-399 mg/ml iodine concentration is a diagnostic tool used in imaging procedures. It helps to enhance the visibility of specific areas in the body, aiding in accurate diagnosis. It's safe and generally well-tolerated by patients.

5,400 services35 patients

Injection, denosumab, 1 mg J0897

Denosumab is a medication given via injection to strengthen your bones. It works by slowing down the cells that break down bone, improving bone density and reducing the risk of fractures. It's often used for osteoporosis treatment.

5,160 services39 patients

Injection, dexamethasone sodium phosphate, 1 mg J1100

Dexamethasone sodium phosphate is a medication given via injection. It is a type of steroid that helps reduce inflammation and immune responses. It can be used to treat a variety of conditions, such as allergies, skin conditions, arthritis, and more.

4,176 services47 patients

Complete blood cell count (red cells, white blood cell, platelets), automated test and automated differential white blood cell count 85025

A Complete Blood Cell Count is a common test that measures various components of the blood, including red cells (carry oxygen), white cells (fight infection), and platelets (help blood clot). An automated test ensures accuracy. The differential count provides detailed information about white cell types.

2,302 services425 patients

Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more 99214

This is a routine check-up for patients who have previously visited our clinic. It involves a comprehensive review of your health and any ongoing treatments. The consultation lasts between 30-39 minutes, allowing enough time to discuss any concerns.

1,574 services453 patients

Insertion of needle into vein for collection of blood sample 36415

This procedure involves inserting a small needle into a vein, typically in your arm, to collect a blood sample. It's a quick and simple process to help diagnose or monitor health conditions. You may feel a small prick, but discomfort is minimal.

1,482 services383 patients

Blood test, comprehensive group of blood chemicals 80053

A comprehensive group of blood chemicals test, also known as a comprehensive metabolic panel, is a blood test that measures your sugar level, electrolyte and fluid balance, kidney function, and liver function. This helps to check your body's overall health.

1,322 services359 patients

Injection, palonosetron hcl, 25 mcg J2469

Palonosetron HCL is an injection used to prevent nausea and vomiting caused by chemotherapy. It works by blocking a natural substance (serotonin) in the body that can cause vomiting. This helps improve your comfort during cancer treatment.

640 services13 patients

Administration of chemotherapy into vein, 1 hour or less 96413

Chemotherapy is a treatment that uses drugs to destroy cancer cells. When administered into a vein, it's often through an IV. This procedure usually lasts 1 hour or less. You may feel a slight pinch as the needle is inserted, but it's generally painless.

574 services82 patients

Injection of drug or substance under skin or into muscle 96372

This procedure involves administering medication directly under the skin or into a muscle. A small needle is used to inject the drug, allowing it to be absorbed quickly into the bloodstream. It's a common method for delivering a variety of medications.

482 services57 patients

Infusion, normal saline solution, 250 cc J7050

An infusion of normal saline solution, 250 cc, involves administering a sterile saltwater solution into your body through a vein, usually in your arm. This helps to replenish fluids, maintain hydration, and balance electrolytes in your body.

463 services30 patients

Injection, magnesium sulfate, per 500 mg J3475

Magnesium sulfate injection, per 500 mg, is a medication administered to manage certain health conditions. It aids in controlling seizures in conditions like eclampsia and in managing severe asthma attacks. It's also used to prevent premature labor in pregnant women.

462 services17 patients

Injection, carboplatin, 50 mg J9045

Carboplatin is a chemotherapy drug used to treat various types of cancer by slowing or stopping the growth of cancer cells. The 50 mg injection is administered into a vein by a healthcare professional. Side effects may occur.

429 services13 patients

Infusion into a vein for therapy, prevention, or diagnosis, additional sequential infusion, 1 hour or less 96367

This procedure involves injecting fluids or medication directly into your vein. It's used for treatment, prevention, or diagnosis. An additional sequential infusion may be given within an hour if needed. This helps to ensure the medicine is distributed effectively in your body.

419 services56 patients

Ferritin (blood protein) level 82728

A Ferritin level test measures the amount of ferritin, a protein that stores iron, in your blood. It helps determine how much iron your body is storing. If levels are low, it may indicate iron deficiency, while high levels could signify conditions like iron overload.

316 services148 patients

Cyanocobalamin (vitamin b-12) level 82607

A Cyanocobalamin (Vitamin B-12) level test is a blood test that checks the amount of Vitamin B-12 in your body. This vitamin is vital for nerve function and the creation of red blood cells. Low or high levels could indicate a potential health issue.

312 services156 patients

Folic acid level, serum 82746

A Folic Acid Level, Serum test measures the amount of folic acid, a type of B vitamin, in your blood. This vitamin is important for cell growth and development. It's crucial for your body to function well. If your levels are low, it may indicate a deficiency, which can lead to health issues.

311 services147 patients

Magnesium level 83735

A magnesium level test is a simple blood test that measures the amount of magnesium in your body. Magnesium is a crucial mineral that helps your nerves, muscles, and heart function properly. The test can help detect health conditions like kidney disease or malnutrition.

299 services58 patients

Infusion into a vein for therapy, prevention, or diagnosis, 1 hour or less 96365

This is a procedure where a medical professional inserts a small tube into your vein to deliver medication, nutrients, or fluids directly into your bloodstream. This can be for treatment, prevention, or diagnosis. The process typically takes less than an hour.

199 services61 patients

Administration of non-hormonal anti-neoplastic chemotherapy under skin or into muscle 96401

This procedure involves giving anti-cancer drugs, which don't contain hormones, into the muscle or under the skin. These drugs help to stop the growth of cancer cells. The process is usually quick and done by a healthcare professional.

183 services50 patients

Injection of additional new drug or substance into vein 96375

This procedure involves introducing a new medication or substance into your bloodstream via a vein. It's typically done using a small needle. The substance can help treat various conditions or assist in diagnostic procedures. It's generally safe and monitored by professionals.

174 services34 patients

Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes 99232

Follow-up hospital inpatient care involves daily check-ups while you're admitted in the hospital. Typically, a healthcare provider spends about 25 minutes each day reviewing your condition, adjusting treatment if needed, and answering any questions you might have.

163 services112 patients

Injection, diphenhydramine hcl, up to 50 mg J1200

Diphenhydramine HCL injection is a medicine given to alleviate symptoms of allergies, colds, or hay fever. It can also help with motion sickness and certain symptoms of Parkinson's disease. Up to 50 mg may be administered depending on your condition.

158 services29 patients

Administration of additional new drug or substance into vein, 1 hour or less 96417

This procedure involves introducing a new drug or substance into your vein, typically via an IV drip. It lasts for an hour or less. This method allows the substance to quickly reach your bloodstream, ensuring rapid and effective treatment.

151 services25 patients

Established patient office or other outpatient visit with high level of medical decision making, if using time, 40 minutes or more 99215

This service involves a follow-up appointment for existing patients, lasting between 40 to 54 minutes. During this time, your healthcare provider will assess your current health status, discuss any changes or concerns, review your treatment plan, and answer any questions you may have.

137 services77 patients

Administration of chemotherapy into vein, each additional hour 96415

Chemotherapy is a treatment method that uses drugs to destroy cancer cells. The drugs are administered into a vein, usually in the arm. Each additional hour of chemotherapy allows for more of the medication to enter your bloodstream to fight against the cancer cells.

135 services25 patients

Injection, vitamin b-12 cyanocobalamin, up to 1000 mcg J3420

This is a procedure where a small dose of Vitamin B-12, also known as Cyanocobalamin, is injected into your body. This vitamin is essential for nerve function and the production of red blood cells. It's often used to treat vitamin B-12 deficiency.

134 services19 patients

Blood test, thyroid stimulating hormone (tsh) 84443

A TSH blood test measures the level of thyroid stimulating hormone in your body. This hormone is produced by the pituitary gland and regulates how your thyroid works. It's a simple procedure where a small amount of blood is drawn from your arm for analysis.

133 services54 patients

Infusion into a vein for hydration, 31-60 minutes 96360

This is a procedure where a sterile solution is administered into your vein to help restore body fluid balance. It typically lasts between 31-60 minutes. It's a safe, common treatment for dehydration or to deliver medication.

122 services29 patients

Iron level 83540

An iron level test measures the amount of iron in your blood. Iron is crucial for producing hemoglobin, a protein in red blood cells that carries oxygen throughout your body. This test helps identify iron deficiencies or excesses, which can lead to conditions like anemia or hemochromatosis.

119 services87 patients

Iron binding capacity 83550

Iron binding capacity is a blood test that measures how well your body can bind and transport iron. This helps your healthcare provider assess if your body has too little or too much iron, which can indicate certain health conditions.

117 services86 patients

Initial hospital care with moderate level of medical decision making, if using time, at least 75 minutes 99223

Initial hospital inpatient care per day, typically 70 minutes, refers to the daily medical service provided to patients admitted to the hospital. This includes a comprehensive evaluation, diagnosis, treatment plan, and monitoring of your health condition. It ensures your well-being during your hospital stay.

98 services86 patients

Established patient office or other outpatient visit with low level od decision making, if using time, 20 minutes or more 99213

This is a routine visit for patients who have already been seen by the healthcare provider. During this approximately 20-29 minute appointment, your health status will be evaluated and any necessary treatments or tests will be discussed. It's a chance to address any health concerns you may have.

96 services85 patients

Telephone medical discussion with physician, 5-10 minutes 99441

A telephone medical discussion with a physician is a brief, 5-10 minute call where you can discuss your health concerns. It's a convenient way to receive medical advice without needing to visit a clinic. It's important to prepare questions in advance to make the most of this time.

94 services69 patients

Carcinoembryonic antigen (cea) protein level 82378

Carcinoembryonic Antigen (CEA) protein level is a blood test often used in cancer care. It measures the amount of CEA protein in your blood, which can increase in cases of certain types of cancer. It's used to monitor treatment progress and check for cancer recurrence.

85 services20 patients

Lactate dehydrogenase (enzyme) level 83615

A Lactate Dehydrogenase level test measures the amount of this enzyme in your body. It's often done when tissue damage is suspected, as high levels can indicate issues like heart disease, lung disease, liver disease, or blood disorders. This test helps in diagnosing and monitoring these conditions.

73 services46 patients

Infusion into a vein for hydration, each additional hour 96361

This procedure involves delivering fluids directly into your vein to keep your body hydrated. It is typically done when oral hydration is insufficient. Each additional hour means more fluid is infused to ensure adequate hydration.

73 services20 patients

Infusion into a vein for therapy, prevention, or diagnosis, each additional hour 96366

This procedure involves delivering medication, fluids, or nutrients directly into your vein. This is done to treat, prevent, or diagnose various conditions. Each additional hour refers to the extended time you may need to receive these substances for optimal results.

70 services14 patients

Phosphate level 84100

A phosphate level test measures the amount of phosphate in your blood. Phosphate is a chemical that contains the mineral phosphorus, crucial for energy production, muscle and nerve function, and bone growth. Imbalances may indicate kidney disease or other health issues.

65 services36 patients

New patient office or other outpatient visit with moderate level of medical decision making, if using time, 45 minutes or more 99204

This is a first-time office or outpatient visit lasting between 45-59 minutes. The healthcare provider evaluates your health, discusses your medical history, and may suggest further tests or treatments. It's an opportunity to ask questions and understand your health better.

65 services65 patients

Fluorodeoxyglucose f-18 fdg, diagnostic, per study dose, up to 45 millicuries A9552

Fluorodeoxyglucose F-18 FDG is a radioactive drug used in PET scans. It helps doctors see how your tissues and organs are functioning. The drug is given in a specific dose, up to 45 millicuries, depending on your body size and the type of scan.

65 services57 patients

Thyroxine (thyroid chemical), free 84439

The Thyroxine (thyroid chemical), free test is a blood test that measures the level of free T4 in your body. T4 is a hormone produced by your thyroid gland and is essential for growth and metabolism. If your T4 levels are too high or too low, it could indicate a thyroid disorder.

58 services33 patients

New patient office or other outpatient visit with a high level of medical decision making, if using time, 60 minutes or more 99205

This is a first-time patient visit where a healthcare professional spends 60-74 minutes with you. It involves a comprehensive evaluation, including your medical history and current health condition. They'll also advise on preventive health measures and formulate a treatment plan if needed.

52 services52 patients

Nuclear medicine study from skull base to mid-thigh with ct scan 78815

A nuclear medicine study from skull base to mid-thigh with a CT scan involves using a small amount of radioactive material and CT imaging to examine body tissues and organs. This helps detect any abnormalities by providing detailed images of the body's internal structure.

49 services41 patients

Ct scan of abdomen and pelvis with contrast 74177

A CT scan of the abdomen and pelvis with contrast is an imaging procedure. A special dye, called contrast, is used to make certain areas more visible. This can help identify issues such as infections, tumors, or other abnormalities. The procedure is painless and usually takes about 30 minutes.

44 services29 patients

Ct scan of chest with contrast 71260

A CT scan of the chest with contrast is an imaging procedure. A special dye (contrast) is used to highlight specific areas in your body, providing clearer pictures of your chest. This helps in diagnosing conditions related to your lungs, heart, and other chest structures.

43 services28 patients

Subsequent hospital care with moderate levelof medical decision making, if using time, at least 50 minutes 99233

Follow-up hospital inpatient care per day typically involves a 35-minute check-up by your healthcare provider. This service includes monitoring your health progress, adjusting your treatment plan if needed, and answering any questions you may have about your condition or care.

42 services35 patients

Manual urinalysis test with examination using microscope, non-automated 81000

A manual urinalysis test involves studying a urine sample under a microscope. This non-automated method helps identify any abnormal substances present. It's a useful tool for detecting potential health concerns early. The process is simple and non-invasive.

41 services15 patients

Irrigation of implanted venous access drug delivery device 96523

Irrigation of an implanted venous access drug delivery device is a procedure to clean or unblock the device. This device is implanted under your skin to allow easy, frequent, and long-term access to your veins for medication delivery. The process involves flushing the device with a sterile solution to ensure it works properly.

26 services13 patients

Initial hospital care with straightforward or low-level medical decision making, if using time, at least 55 minutes 99222

Initial hospital inpatient care is a service where a healthcare provider spends about 50 minutes per day overseeing your care while you're admitted in the hospital. This includes reviewing your health status, planning your treatment, and ensuring your safety and comfort.

26 services25 patients

Nuclear medicine study whole body with ct scan 78816

A Nuclear Medicine Study with a CT Scan is a diagnostic procedure. It uses a small amount of radioactive substance and a CT scan to create detailed images of your body. These images help doctors diagnose, monitor, and treat various conditions.

19 services18 patients

Telephone medical discussion with physician, 11-20 minutes 99442

This is a service where you have a phone conversation with your doctor for 11-20 minutes. It's used for discussing health concerns, reviewing test results, or managing ongoing conditions. It's a convenient way to receive medical advice without an in-person visit.

14 services13 patients

Hospital Affiliations CMS Care Compare 5

Hospitals where this provider delivers care, identified from recent Medicare claims and place-of-service records.

Cleveland Clinic Martin North Hospital

Acute Care Hospitals · Stuart, FL

2/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number100044

Location200 SE Hospital AveStuart, FL 34994 · Martin County

Emergency services Birthing friendly

Hca Florida Lawnwood Hospital

Acute Care Hospitals · Fort Pierce, FL

1/5 CMS rating

OwnershipProprietary

CMS Certification Number100246

Location1700 S 23rd StFort Pierce, FL 34950 · St. Lucie County

Emergency services Birthing friendly

Hca Florida Raulerson Hospital

Acute Care Hospitals · Okeechobee, FL

3/5 CMS rating

OwnershipProprietary

CMS Certification Number100252

Location1796 Hwy 441 NorthOkeechobee, FL 34972 · Okeechobee County

Jupiter Medical Center

Acute Care Hospitals · Jupiter, FL

4/5 CMS rating

OwnershipVoluntary non-profit - Private

CMS Certification Number100253

Location1210 S Old Dixie HwyJupiter, FL 33458 · Palm Beach County

Emergency services Birthing friendly

St Lucie Medical Center

Acute Care Hospitals · Port Saint Lucie, FL

1/5 CMS rating

OwnershipProprietary

CMS Certification Number100260

Location1800 SE Tiffany AvePort Saint Lucie, FL 34952 · St. Lucie County

Emergency services Birthing friendly

Physician Visit Costs CMS claims · ZIP area

Typical Medicare office-visit costs in the 34994 ZIP code area, from fee-for-service claims. These are area statistics, not this provider’s prices; actual charges vary by service and coverage.

New Patient

$179.05 typical visit price

range $58.56 – $179.05

Typical copayment $44.76 (range $14.64 – $44.76)

Most-billed visit code 99205

Established Patient

$103.21 typical visit price

range $18.44 – $144.68

Typical copayment $25.80 (range $4.61 – $36.17)

Most-billed visit code 99214

Amounts reflect what Medicare beneficiaries in this ZIP area are typically charged for office visits. Patients with other coverage should check their individual plans.

Medicare Quality Performance CMS QPP · MIPS

Performance in the CMS Quality Payment Program: the MIPS final score across four weighted categories, and the individual quality measures reported to Medicare.

89.89/100

MIPS Final ScoreMerit-based Incentive Payment System · CMS Quality Payment Program

Scored through an Alternative Payment Model

Quality

75.75

Promoting Interoperability

100

Improvement Activities

Referred Medical Equipment & Supplies CMS DME claims

Durable medical equipment, devices and supplies this provider ordered from DME suppliers for patients, from Medicare fee-for-service claims.

Capecitabine, oral, 500 mg J8521

Treatment-Treatment - Miscellaneous · category RX029N

1 supplier11 claims700 services$0.61 avg. paid by Medicare

Dollar amounts are the average Medicare paid the supplier per service. They are not the cost to the patient.

Other Providers at the Same Location NPPES 5

Providers registered at the same practice address, or within the immediate area, according to the NPPES registry.

DR. CYNTHIA IVY LOPEZ MD

Internal Medicine (Hematology & Oncology)