JOHN DAVID BISOGNANO MD
Prescription History 1992747752
Internal Medicine - Cardiovascular Disease in Ann Arbor, MI

NPI Status: Active since June 12, 2006

Contact Information

24 FRANK LLOYD WRIGHT DR
ANN ARBOR, MI
ZIP 48105
Phone: (888) 287-1082

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Prescription History for Informed Healthcare Decisions

Explore the verified Medicare Part D prescription history, volume metrics, and calculated drug costs for JOHN DAVID BISOGNANO MD, an active Cardiovascular Disease specialist practicing in Ann Arbor, MI. Our medical registry currently tracks 40 unique pharmaceutical formulations prescribed by this provider, representing an estimated volume of 2,301 documented patient claims. Among these therapy options, the most frequently utilized medication is Atorvastatin Calcium, which accounts for 268 claims alone.


Amlodipine Besylate

Generic Formulation: Amlodipine BesylateSpecialty: Cardiology
Provider Metrics Summary
Total Claims 160
30-Day Fills 446.0
Days Supply 13,380
MI State Average Benchmarks
Peer Average Claims130.0
Peer Average 30-Day Fills307.7
Peer Average Days Supply9,167
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $1,809.26 across this reporting matrix range.

Provider Avg Cost Per Claim

$11.31

State Avg Cost Per Claim

$8.17

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.

Therapeutic Applications

Amlodipine is used with or without other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Amlodipine belongs to a class of drugs known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily. Amlodipine is also used to prevent certain types of chest pain (angina). It may help to increase your ability to exercise and decrease the frequency of angina attacks. It should not be used to treat attacks of chest pain when they occur. Use other medications (such as sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor.

Amlodipine Besylate-Benazepril

Generic Formulation: Amlodipine Besylate/BenazeprilSpecialty: Cardiology
Provider Metrics Summary
Total Claims 65
30-Day Fills 189.0
Days Supply 5,637
MI State Average Benchmarks
Peer Average Claims27.0
Peer Average 30-Day Fills70.7
Peer Average Days Supply2,115
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 140.7% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $2,699.26 across this reporting matrix range.

Provider Avg Cost Per Claim

$41.53

State Avg Cost Per Claim

$38.22

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

This product is a combination of two drugs: a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril). It is used to treat high blood pressure. It works by relaxing blood vessels so that blood can flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

Amoxicillin

Generic Formulation: AmoxicillinSpecialty: Cardiology
Provider Metrics Summary
Total Claims 12
30-Day Fills 14.0
Days Supply 107
MI State Average Benchmarks
Peer Average Claims38.0
Peer Average 30-Day Fills39.0
Peer Average Days Supply266
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 68.4% less volume than the regional standard for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $8.01 across this reporting matrix range.

Provider Avg Cost Per Claim

$0.67

State Avg Cost Per Claim

$2.94

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.

Therapeutic Applications

Amoxicillin is used to treat a wide variety of bacterial infections. This medication is a penicillin-type antibiotic. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. Amoxicillin is also used with other medications to treat stomach/intestinal ulcers caused by the bacteria H. pylori and to prevent the ulcers from returning.

Atenolol-Chlorthalidone

Generic Formulation: Atenolol/ChlorthalidoneSpecialty: Cardiology
Provider Metrics Summary
Total Claims 12
30-Day Fills 36.0
Days Supply 1,080
MI State Average Benchmarks
Peer Average Claims19.0
Peer Average 30-Day Fills47.9
Peer Average Days Supply1,434
Conservative Utilization

This provider writes prescriptions for this formulation 36.8% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $746.12 across this reporting matrix range.

Provider Avg Cost Per Claim

$62.18

State Avg Cost Per Claim

$46.42

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

This medication is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains 2 medications: atenolol and chlorthalidone. Atenolol belongs to a class of drugs known as beta blockers. It works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect lowers the heart rate, blood pressure, and strain on the heart. Chlorthalidone is a water pill (diuretic) and causes your body to get rid of extra salt and water. This effect may increase the amount of urine you make when you first start the medication. It also helps to relax the blood vessels so that blood can flow more easily. These medications are used together when 1 drug alone is not controlling your blood pressure. Your doctor may direct you to start taking the individual medications first, and then switch you over to this combination product if this is the best dose combination for you.

Atorvastatin Calcium

Generic Formulation: Atorvastatin CalciumSpecialty: Cardiology
Provider Metrics Summary
Total Claims 268
30-Day Fills 794.0
Days Supply 23,796
MI State Average Benchmarks
Peer Average Claims182.0
Peer Average 30-Day Fills441.0
Peer Average Days Supply13,142
Elevated Utilization

This provider maintains an active emphasis on this therapeutic option, recording 47.3% more claims than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $5,623.50 across this reporting matrix range.

Provider Avg Cost Per Claim

$20.98

State Avg Cost Per Claim

$15.97

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A pyrrole and heptanoic acid derivative, HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITOR (statin), and ANTICHOLESTEREMIC AGENT that is used to reduce serum levels of LDL-CHOLESTEROL; APOLIPOPROTEIN B; and TRIGLYCERIDES. It is used to increase serum levels of HDL-CHOLESTEROL in the treatment of HYPERLIPIDEMIAS, and for the prevention of CARDIOVASCULAR DISEASES in patients with multiple risk factors.

Therapeutic Applications

Atorvastatin is used along with a proper diet to help lower bad cholesterol and fats (such as LDL, triglycerides) and raise good cholesterol (HDL) in the blood. It belongs to a group of drugs known as statins. It works by reducing the amount of cholesterol made by the liver. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

Benazepril Hcl

Generic Formulation: Benazepril HclSpecialty: Cardiology
Provider Metrics Summary
Total Claims 16
30-Day Fills 48.0
Days Supply 1,440
MI State Average Benchmarks
Peer Average Claims21.0
Peer Average 30-Day Fills54.3
Peer Average Days Supply1,623
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $429.87 across this reporting matrix range.

Provider Avg Cost Per Claim

$26.87

State Avg Cost Per Claim

$15.62

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Benazepril is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Benazepril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily.

Carvedilol

Generic Formulation: CarvedilolSpecialty: Cardiology
Provider Metrics Summary
Total Claims 37
30-Day Fills 109.0
Days Supply 3,270
MI State Average Benchmarks
Peer Average Claims59.0
Peer Average 30-Day Fills136.2
Peer Average Days Supply4,047
Conservative Utilization

This provider writes prescriptions for this formulation 37.3% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $516.68 across this reporting matrix range.

Provider Avg Cost Per Claim

$13.96

State Avg Cost Per Claim

$12.35

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A carbazole and propanol derivative that acts as a non-cardioselective beta blocker and vasodilator. It has blocking activity for ALPHA 1 ADRENERGIC RECEPTORS and, at higher doses, may function as a blocker of CALCIUM CHANNELS; it also has antioxidant properties. Carvedilol is used in the treatment of HYPERTENSION; ANGINA PECTORIS; and HEART FAILURE. It can also reduce the risk of death following MYOCARDIAL INFARCTION.

Therapeutic Applications

Carvedilol is used to treat high blood pressure and heart failure. It is also used after a heart attack to improve the chance of survival if your heart is not pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers your heart rate, blood pressure, and strain on your heart. Carvedilol belongs to a class of drugs known as alpha and beta blockers.

Chlorthalidone

Generic Formulation: ChlorthalidoneSpecialty: Cardiology
Provider Metrics Summary
Total Claims 38
30-Day Fills 108.0
Days Supply 3,207
MI State Average Benchmarks
Peer Average Claims29.0
Peer Average 30-Day Fills69.2
Peer Average Days Supply2,068
Elevated Utilization

This provider maintains an active emphasis on this therapeutic option, recording 31.0% more claims than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $1,049.21 across this reporting matrix range.

Provider Avg Cost Per Claim

$27.61

State Avg Cost Per Claim

$29.05

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.

Therapeutic Applications

Chlorthalidone is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to reduce extra salt and water in the body caused by conditions such as heart failure, liver disease, and kidney disease. Decreasing extra salt and water in the body helps to decrease swelling (edema) and breathing problems caused by fluid in the lungs. Chlorthalidone is a water pill (diuretic). It increases the amount of urine you make, especially when you first start the medication. It also helps to relax the blood vessels so that blood can flow more easily.

Clonidine

Generic Formulation: ClonidineSpecialty: Cardiology
Provider Metrics Summary
Total Claims 12
30-Day Fills 28.4
Days Supply 846
MI State Average Benchmarks
Peer Average Claims18.0
Peer Average 30-Day Fills25.8
Peer Average Days Supply741
Conservative Utilization

This provider writes prescriptions for this formulation 33.3% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $3,753.76 across this reporting matrix range.

Provider Avg Cost Per Claim

$312.81

State Avg Cost Per Claim

$139.97

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.

Therapeutic Applications

This medication is used alone or with other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Clonidine belongs to a class of drugs (central alpha agonists) that act in the brain to lower blood pressure. It works by relaxing blood vessels so blood can flow more easily.

Clopidogrel

Generic Formulation: Clopidogrel BisulfateSpecialty: Cardiology
Provider Metrics Summary
Total Claims 14
30-Day Fills 42.0
Days Supply 1,260
MI State Average Benchmarks
Peer Average Claims55.0
Peer Average 30-Day Fills126.7
Peer Average Days Supply3,767
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 74.5% less volume than the regional standard for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $188.47 across this reporting matrix range.

Provider Avg Cost Per Claim

$13.46

State Avg Cost Per Claim

$16.93

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A ticlopidine analog and platelet purinergic P2Y receptor antagonist that inhibits adenosine diphosphate-mediated PLATELET AGGREGATION. It is used to prevent THROMBOEMBOLISM in patients with ARTERIAL OCCLUSIVE DISEASES; MYOCARDIAL INFARCTION; STROKE; or ATRIAL FIBRILLATION.

Therapeutic Applications

Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots. It is an antiplatelet drug. It helps keep blood flowing smoothly in your body.

Diltiazem 24hr Er (Cd)

Generic Formulation: Diltiazem HclSpecialty: Cardiology
Provider Metrics Summary
Total Claims 21
30-Day Fills 63.0
Days Supply 1,890
MI State Average Benchmarks
Peer Average Claims33.0
Peer Average 30-Day Fills79.0
Peer Average Days Supply2,356
Conservative Utilization

This provider writes prescriptions for this formulation 36.4% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $1,162.86 across this reporting matrix range.

Provider Avg Cost Per Claim

$55.37

State Avg Cost Per Claim

$51.92

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Diltiazem is used to prevent chest pain (angina). It may help to increase your ability to exercise and decrease how often you may get angina attacks. Diltiazem is called a calcium channel blocker. It works by relaxing blood vessels in the body and heart and lowers the heart rate. Blood can flow more easily and your heart works less hard to pump blood.

Eliquis

Generic Formulation: ApixabanSpecialty: Cardiology
Provider Metrics Summary
Total Claims 73
30-Day Fills 159.0
Days Supply 4,740
MI State Average Benchmarks
Peer Average Claims76.0
Peer Average 30-Day Fills135.2
Peer Average Days Supply3,873
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $88,090.26 across this reporting matrix range.

Provider Avg Cost Per Claim

$1,206.72

State Avg Cost Per Claim

$879.34

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery. With atrial fibrillation, part of the heart does not beat the way it should. This can lead to blood clots forming, which can travel to other parts of your body (such as the lungs or legs) or increase your risk for stroke. In the United States, apixaban is also approved to treat certain types of blood clots (deep vein thrombosis-DVT, pulmonary embolus-PE) and to prevent them from forming again. Apixaban is an anticoagulant that works by blocking certain clotting proteins in your blood.

Ezetimibe

Generic Formulation: EzetimibeSpecialty: Cardiology
Provider Metrics Summary
Total Claims 139
30-Day Fills 399.0
Days Supply 11,970
MI State Average Benchmarks
Peer Average Claims37.0
Peer Average 30-Day Fills95.2
Peer Average Days Supply2,847
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 275.7% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $5,685.11 across this reporting matrix range.

Provider Avg Cost Per Claim

$40.90

State Avg Cost Per Claim

$58.78

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

An azetidine derivative and ANTICHOLESTEREMIC AGENT that inhibits intestinal STEROL absorption. It is used to reduce total CHOLESTEROL; LDL CHOLESTEROL, and APOLIPOPROTEINS B in the treatment of HYPERLIPIDEMIAS.

Therapeutic Applications

Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as statins or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.

Felodipine Er

Generic Formulation: FelodipineSpecialty: Cardiology
Provider Metrics Summary
Total Claims 28
30-Day Fills 72.0
Days Supply 2,160
MI State Average Benchmarks
Peer Average Claims23.0
Peer Average 30-Day Fills57.0
Peer Average Days Supply1,698
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $1,043.79 across this reporting matrix range.

Provider Avg Cost Per Claim

$37.28

State Avg Cost Per Claim

$33.58

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.

Therapeutic Applications

Felodipine is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Felodipine is known as a calcium channel blocker. By blocking calcium, this medication relaxes and widens blood vessels so blood can flow more easily.

Furosemide

Generic Formulation: FurosemideSpecialty: Cardiology
Provider Metrics Summary
Total Claims 54
30-Day Fills 97.4
Days Supply 2,922
MI State Average Benchmarks
Peer Average Claims73.0
Peer Average 30-Day Fills145.3
Peer Average Days Supply4,237
Conservative Utilization

This provider writes prescriptions for this formulation 26.0% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $394.63 across this reporting matrix range.

Provider Avg Cost Per Claim

$7.31

State Avg Cost Per Claim

$6.12

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.

Therapeutic Applications

Furosemide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Furosemide is a water pill (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt.

Hydralazine Hcl

Generic Formulation: Hydralazine HclSpecialty: Cardiology
Provider Metrics Summary
Total Claims 35
30-Day Fills 97.5
Days Supply 2,897
MI State Average Benchmarks
Peer Average Claims40.0
Peer Average 30-Day Fills76.8
Peer Average Days Supply2,251
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $703.50 across this reporting matrix range.

Provider Avg Cost Per Claim

$20.10

State Avg Cost Per Claim

$17.61

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Hydralazine is used with or without other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydralazine is called a vasodilator. It works by relaxing blood vessels so blood can flow through the body more easily.

Hydrochlorothiazide

Generic Formulation: HydrochlorothiazideSpecialty: Cardiology
Provider Metrics Summary
Total Claims 35
30-Day Fills 101.0
Days Supply 3,007
MI State Average Benchmarks
Peer Average Claims69.0
Peer Average 30-Day Fills171.2
Peer Average Days Supply5,118
Conservative Utilization

This provider writes prescriptions for this formulation 49.3% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $329.26 across this reporting matrix range.

Provider Avg Cost Per Claim

$9.41

State Avg Cost Per Claim

$5.71

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.

Therapeutic Applications

This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydrochlorothiazide belongs to a class of drugs known as diuretics/water pills. It works by causing you to make more urine. This helps your body get rid of extra salt and water. This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.

Indapamide

Generic Formulation: IndapamideSpecialty: Cardiology
Provider Metrics Summary
Total Claims 19
30-Day Fills 53.0
Days Supply 1,590
MI State Average Benchmarks
Peer Average Claims25.0
Peer Average 30-Day Fills63.2
Peer Average Days Supply1,892
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $430.34 across this reporting matrix range.

Provider Avg Cost Per Claim

$22.65

State Avg Cost Per Claim

$22.90

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.

Therapeutic Applications

This medication is used to treat high blood pressure. Indapamide is also used to reduce extra fluid in the body (edema) caused by heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Indapamide belongs to a class of drugs known as diuretics/water pills. It works by causing you to make more urine. This helps your body get rid of extra salt and water. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.

Irbesartan

Generic Formulation: IrbesartanSpecialty: Cardiology
Provider Metrics Summary
Total Claims 69
30-Day Fills 191.0
Days Supply 5,730
MI State Average Benchmarks
Peer Average Claims30.0
Peer Average 30-Day Fills78.4
Peer Average Days Supply2,346
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 130.0% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $2,737.52 across this reporting matrix range.

Provider Avg Cost Per Claim

$39.67

State Avg Cost Per Claim

$37.37

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.

Therapeutic Applications

Irbesartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Irbesartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily.

Irbesartan-Hydrochlorothiazide

Generic Formulation: Irbesartan/HydrochlorothiazideSpecialty: Cardiology
Provider Metrics Summary
Total Claims 17
30-Day Fills 30.0
Days Supply 900
MI State Average Benchmarks
Peer Average Claims23.0
Peer Average 30-Day Fills60.2
Peer Average Days Supply1,800
Conservative Utilization

This provider writes prescriptions for this formulation 26.1% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $638.61 across this reporting matrix range.

Provider Avg Cost Per Claim

$37.57

State Avg Cost Per Claim

$44.23

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

This drug is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: irbesartan and hydrochlorothiazide. Irbesartan is an angiotensin receptor blocker (ARB) and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a water pill (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water.

Isosorbide Mononitrate Er

Generic Formulation: Isosorbide MononitrateSpecialty: Cardiology
Provider Metrics Summary
Total Claims 23
30-Day Fills 67.0
Days Supply 2,010
MI State Average Benchmarks
Peer Average Claims42.0
Peer Average 30-Day Fills95.8
Peer Average Days Supply2,849
Conservative Utilization

This provider writes prescriptions for this formulation 45.2% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $849.32 across this reporting matrix range.

Provider Avg Cost Per Claim

$36.93

State Avg Cost Per Claim

$19.59

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). This medication belongs to a class of drugs known as nitrates. It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medication will not relieve chest pain once it occurs. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Other medications may be prescribed by your doctor for these conditions. Consult your doctor for more details.

Lisinopril

Generic Formulation: LisinoprilSpecialty: Cardiology
Provider Metrics Summary
Total Claims 50
30-Day Fills 138.0
Days Supply 4,140
MI State Average Benchmarks
Peer Average Claims125.0
Peer Average 30-Day Fills305.7
Peer Average Days Supply9,117
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 60.0% less volume than the regional standard for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $505.15 across this reporting matrix range.

Provider Avg Cost Per Claim

$10.10

State Avg Cost Per Claim

$9.00

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors), orally active, that has been used in the treatment of hypertension and congestive heart failure.

Therapeutic Applications

Lisinopril is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure and to improve survival after a heart attack. Lisinopril belongs to a class of drugs known as ACE inhibitors. It works by relaxing blood vessels so blood can flow more easily.

Losartan Potassium

Generic Formulation: Losartan PotassiumSpecialty: Cardiology
Provider Metrics Summary
Total Claims 63
30-Day Fills 181.0
Days Supply 5,431
MI State Average Benchmarks
Peer Average Claims106.0
Peer Average 30-Day Fills262.3
Peer Average Days Supply7,829
Conservative Utilization

This provider writes prescriptions for this formulation 40.6% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $852.38 across this reporting matrix range.

Provider Avg Cost Per Claim

$13.53

State Avg Cost Per Claim

$16.32

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.

Therapeutic Applications

Losartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Losartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily.

Metoprolol Succinate

Generic Formulation: Metoprolol SuccinateSpecialty: Cardiology
Provider Metrics Summary
Total Claims 195
30-Day Fills 527.0
Days Supply 15,780
MI State Average Benchmarks
Peer Average Claims102.0
Peer Average 30-Day Fills248.2
Peer Average Days Supply7,400
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 91.2% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $4,324.97 across this reporting matrix range.

Provider Avg Cost Per Claim

$22.18

State Avg Cost Per Claim

$25.47

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.

Therapeutic Applications

This medication is a beta-blocker used to treat chest pain (angina), heart failure, and high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the action of certain natural chemicals in your body (such as epinephrine) that affect the heart and blood vessels. This lowers heart rate, blood pressure, and strain on the heart.

Metoprolol Tartrate

Generic Formulation: Metoprolol TartrateSpecialty: Cardiology
Provider Metrics Summary
Total Claims 39
30-Day Fills 115.0
Days Supply 3,450
MI State Average Benchmarks
Peer Average Claims72.0
Peer Average 30-Day Fills161.5
Peer Average Days Supply4,785
Conservative Utilization

This provider writes prescriptions for this formulation 45.8% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $380.90 across this reporting matrix range.

Provider Avg Cost Per Claim

$9.77

State Avg Cost Per Claim

$8.40

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.

Therapeutic Applications

Metoprolol is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is also used to treat chest pain (angina) and to improve survival after a heart attack. Metoprolol belongs to a class of drugs known as beta blockers. It works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect lowers the heart rate, blood pressure, and strain on the heart.

Nitroglycerin

Generic Formulation: NitroglycerinSpecialty: Cardiology
Provider Metrics Summary
Total Claims 24
30-Day Fills 36.8
Days Supply 987
MI State Average Benchmarks
Peer Average Claims30.0
Peer Average 30-Day Fills34.9
Peer Average Days Supply741
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $499.95 across this reporting matrix range.

Provider Avg Cost Per Claim

$20.83

State Avg Cost Per Claim

$21.55

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.

Therapeutic Applications

Nitroglycerin ointment is used to prevent chest pain (angina) in people with a certain heart condition (coronary artery disease). This medication belongs to a class of drugs known as nitrates. Angina occurs when the heart muscle is not getting enough blood. This drug works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medication will not relieve chest pain once it occurs. It is also not intended to be used just before physical activities (such as exercise, sexual activity) to prevent chest pain. Other medications may be needed in these situations. Consult your doctor for more details.

Olmesartan Medoxomil

Generic Formulation: Olmesartan MedoxomilSpecialty: Cardiology
Provider Metrics Summary
Total Claims 18
30-Day Fills 54.0
Days Supply 1,620
MI State Average Benchmarks
Peer Average Claims28.0
Peer Average 30-Day Fills68.7
Peer Average Days Supply2,054
Conservative Utilization

This provider writes prescriptions for this formulation 35.7% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $601.17 across this reporting matrix range.

Provider Avg Cost Per Claim

$33.40

State Avg Cost Per Claim

$37.75

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

An ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER that is used to manage HYPERTENSION.

Therapeutic Applications

Olmesartan is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Olmesartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily.

Omeprazole

Generic Formulation: OmeprazoleSpecialty: Cardiology
Provider Metrics Summary
Total Claims 18
30-Day Fills 40.0
Days Supply 1,200
MI State Average Benchmarks
Peer Average Claims105.0
Peer Average 30-Day Fills234.4
Peer Average Days Supply6,980
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 82.9% less volume than the regional standard for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $270.30 across this reporting matrix range.

Provider Avg Cost Per Claim

$15.02

State Avg Cost Per Claim

$15.60

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

Therapeutic Applications

Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). If you are self-treating with this medication, over-the-counter omeprazole products are used to treat frequent heartburn (occurring 2 or more days a week). Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away. For over-the-counter products, carefully read the package instructions to make sure the product is right for you. Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar brand names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.

Potassium Chloride

Generic Formulation: Potassium ChlorideSpecialty: Cardiology
Provider Metrics Summary
Total Claims 20
30-Day Fills 51.3
Days Supply 1,540
MI State Average Benchmarks
Peer Average Claims58.0
Peer Average 30-Day Fills113.2
Peer Average Days Supply3,297
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 65.5% less volume than the regional standard for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $1,005.47 across this reporting matrix range.

Provider Avg Cost Per Claim

$50.27

State Avg Cost Per Claim

$32.36

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.

Therapeutic Applications

This medication is a mineral supplement used to treat or prevent low amounts of potassium in the blood. A normal level of potassium in the blood is important. Potassium helps your cells, kidneys, heart, muscles, and nerves work properly. Most people get enough potassium by eating a well-balanced diet. Some conditions that can lower your body's potassium level include severe prolonged diarrhea and vomiting, hormone problems such as hyperaldosteronism, or treatment with water pills/diuretics.

Praluent Pen

Generic Formulation: AlirocumabSpecialty: Cardiology
Provider Metrics Summary
Total Claims 87
30-Day Fills 94.2
Days Supply 2,660
MI State Average Benchmarks
Peer Average Claims27.0
Peer Average 30-Day Fills39.0
Peer Average Days Supply1,128
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 222.2% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $47,753.52 across this reporting matrix range.

Provider Avg Cost Per Claim

$548.89

State Avg Cost Per Claim

$706.22

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Alirocumab is used by people who have blockage in the heart blood vessels to reduce the risk of heart attack, stroke, and certain types of chest pain that require treatment in a hospital. It is also used by people who have an inherited condition that causes high levels of LDL. Treatment with alirocumab, a proper diet, and cholesterol-lowering drugs can help lower bad cholesterol (LDL) in the blood. Alirocumab belongs to a class of drugs known as monoclonal antibodies. It works by improving how well your body gets rid of LDL cholesterol. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

Pravastatin Sodium

Generic Formulation: Pravastatin SodiumSpecialty: Cardiology
Provider Metrics Summary
Total Claims 30
30-Day Fills 90.0
Days Supply 2,700
MI State Average Benchmarks
Peer Average Claims49.0
Peer Average 30-Day Fills127.2
Peer Average Days Supply3,801
Conservative Utilization

This provider writes prescriptions for this formulation 38.8% less frequently than the standard regional baseline metric for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $734.69 across this reporting matrix range.

Provider Avg Cost Per Claim

$24.49

State Avg Cost Per Claim

$21.40

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

An antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES).

Therapeutic Applications

Pravastatin is used along with a proper diet to help lower bad cholesterol and fats (such as LDL, triglycerides) and raise good cholesterol (HDL) in the blood. It belongs to a group of drugs known as statins. It works by reducing the amount of cholesterol made by the liver. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

Repatha Sureclick

Generic Formulation: EvolocumabSpecialty: Cardiology
Provider Metrics Summary
Total Claims 145
30-Day Fills 152.2
Days Supply 4,286
MI State Average Benchmarks
Peer Average Claims40.0
Peer Average 30-Day Fills58.2
Peer Average Days Supply1,686
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 262.5% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $79,234.27 across this reporting matrix range.

Provider Avg Cost Per Claim

$546.44

State Avg Cost Per Claim

$749.99

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Evolocumab is used along with a proper diet to help lower bad cholesterol (LDL) in the blood. It may be used with other LDL-lowering treatments (such as statin drugs, ezetimibe, LDL apheresis). Evolocumab is also used by people who have heart disease to help prevent heart attacks and strokes. This medication belongs to a class of drugs known as monoclonal antibodies. It works by improving how well your body gets rid of LDL cholesterol. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

Repatha Syringe

Generic Formulation: EvolocumabSpecialty: Cardiology
Provider Metrics Summary
Total Claims 17
30-Day Fills 24.2
Days Supply 700
MI State Average Benchmarks
Peer Average Claims17.0
Peer Average 30-Day Fills25.5
Peer Average Days Supply730
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $14,285.08 across this reporting matrix range.

Provider Avg Cost Per Claim

$840.30

State Avg Cost Per Claim

$755.24

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

Evolocumab is used along with a proper diet to help lower bad cholesterol (LDL) in the blood. It may be used with other LDL-lowering treatments (such as statin drugs, ezetimibe, LDL apheresis). Evolocumab is also used by people who have heart disease to help prevent heart attacks and strokes. This medication belongs to a class of drugs known as monoclonal antibodies. It works by improving how well your body gets rid of LDL cholesterol. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

Rosuvastatin Calcium

Generic Formulation: Rosuvastatin CalciumSpecialty: Cardiology
Provider Metrics Summary
Total Claims 194
30-Day Fills 568.6
Days Supply 17,056
MI State Average Benchmarks
Peer Average Claims72.0
Peer Average 30-Day Fills184.8
Peer Average Days Supply5,530
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 169.4% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $5,239.12 across this reporting matrix range.

Provider Avg Cost Per Claim

$27.01

State Avg Cost Per Claim

$32.48

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A HYDROXYMETHYLGLUTARYL-COA-REDUCTASE INHIBITOR, or statin, that reduces the plasma concentrations of LDL-CHOLESTEROL; APOLIPOPROTEIN B, and TRIGLYCERIDES while increasing HDL-CHOLESTEROL levels in patients with HYPERCHOLESTEROLEMIA and those at risk for CARDIOVASCULAR DISEASES.

Therapeutic Applications

Rosuvastatin is used along with a proper diet to help lower bad cholesterol and fats (such as LDL, triglycerides) and raise good cholesterol (HDL) in the blood. It belongs to a group of drugs known as statins. It works by reducing the amount of cholesterol made by the liver. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps to prevent strokes and heart attacks. In addition to eating a proper diet (such as a low cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Talk with your doctor for more details.

Sotalol

Generic Formulation: Sotalol HclSpecialty: Cardiology
Provider Metrics Summary
Total Claims 12
30-Day Fills 18.0
Days Supply 540
MI State Average Benchmarks
Peer Average Claims33.0
Peer Average 30-Day Fills81.3
Peer Average Days Supply2,425
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 63.6% less volume than the regional standard for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $396.53 across this reporting matrix range.

Provider Avg Cost Per Claim

$33.04

State Avg Cost Per Claim

$29.60

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

This medication is used to treat a serious (possibly life-threatening) type of fast heartbeat called sustained ventricular tachycardia. It is also used to treat certain fast/irregular heartbeats (atrial fibrillation/flutter) in patients with severe symptoms such as weakness and shortness of breath. Sotalol helps to lessen these symptoms. It slows the heart rate and helps the heart to beat more normally and regularly. This medication is both a beta blocker and an anti-arrhythmic.

Spironolactone

Generic Formulation: SpironolactoneSpecialty: Cardiology
Provider Metrics Summary
Total Claims 81
30-Day Fills 243.0
Days Supply 7,290
MI State Average Benchmarks
Peer Average Claims37.0
Peer Average 30-Day Fills86.4
Peer Average Days Supply2,573
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 118.9% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $1,348.18 across this reporting matrix range.

Provider Avg Cost Per Claim

$16.64

State Avg Cost Per Claim

$13.08

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)

Therapeutic Applications

Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat conditions in which the body is making too much of a natural substance (aldosterone). Spironolactone is known as a water pill (potassium-sparing diuretic).

Spironolactone-Hctz

Generic Formulation: Spironolact/HydrochlorothiazidSpecialty: Cardiology
Provider Metrics Summary
Total Claims 12
30-Day Fills 32.0
Days Supply 960
MI State Average Benchmarks
Peer Average Claims25.0
Peer Average 30-Day Fills61.6
Peer Average Days Supply1,839
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 52.0% less volume than the regional standard for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $207.27 across this reporting matrix range.

Provider Avg Cost Per Claim

$17.27

State Avg Cost Per Claim

$55.76

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Therapeutic Applications

This product is used to treat high blood pressure (hypertension), heart failure, or extra fluid in the body (edema). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: spironolactone and hydrochlorothiazide. Both medications are water pills (diuretics) and cause your body to get rid of extra salt and water. This effect helps to relax the blood vessels so that blood can flow more easily and may increase the amount of urine you make when you first start the product. Spironolactone also helps to treat or prevent low blood potassium levels and block the activity of a certain natural substance (aldosterone) that can cause edema. Your doctor may direct you to start taking the individual medications first, and then switch you over to this combination product if this is the best dose combination for you.

Torsemide

Generic Formulation: TorsemideSpecialty: Cardiology
Provider Metrics Summary
Total Claims 93
30-Day Fills 269.2
Days Supply 8,007
MI State Average Benchmarks
Peer Average Claims35.0
Peer Average 30-Day Fills68.2
Peer Average Days Supply1,988
Highly Elevated Utilization

This provider exhibits a high preference for this treatment path, registering a volume 165.7% higher than the standard regional baseline profile for MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $2,360.55 across this reporting matrix range.

Provider Avg Cost Per Claim

$25.38

State Avg Cost Per Claim

$20.66

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A pyridine and sulfonamide derivative that acts as a sodium-potassium chloride symporter inhibitor (loop diuretic). It is used for the treatment of EDEMA associated with CONGESTIVE HEART FAILURE; CHRONIC RENAL INSUFFICIENCY; and LIVER DISEASES. It is also used for the management of HYPERTENSION.

Therapeutic Applications

Torsemide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Torsemide is a water pill (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt.

Warfarin Sodium

Generic Formulation: Warfarin SodiumSpecialty: Cardiology
Provider Metrics Summary
Total Claims 16
30-Day Fills 45.7
Days Supply 1,370
MI State Average Benchmarks
Peer Average Claims38.0
Peer Average 30-Day Fills82.4
Peer Average Days Supply2,366
Highly Conservative Utilization

This provider demonstrates a highly selective approach to this formula, recording 57.9% less volume than the regional standard for practitioners inside MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $316.49 across this reporting matrix range.

Provider Avg Cost Per Claim

$19.78

State Avg Cost Per Claim

$14.40

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.

Therapeutic Applications

This medication is used to treat blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE) and/or to prevent new clots from forming in your body. Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack. Conditions that increase your risk of developing blood clots include a certain type of irregular heart rhythm (atrial fibrillation), heart valve replacement, recent heart attack, and certain surgeries (such as hip/knee replacement). Warfarin is commonly called a blood thinner, but the more correct term is anticoagulant. It helps to keep blood flowing smoothly in your body by decreasing the amount of certain substances (clotting proteins) in your blood.

Xarelto

Generic Formulation: RivaroxabanSpecialty: Cardiology
Provider Metrics Summary
Total Claims 40
30-Day Fills 82.0
Days Supply 2,460
MI State Average Benchmarks
Peer Average Claims41.0
Peer Average 30-Day Fills80.8
Peer Average Days Supply2,339
Standard Average Utilization

This provider's prescribing patterns for this therapeutic formulation sit directly in line with standard baseline averages across MI. Gross expenditures recorded under Medicare program tracking definitions for this provider calculate to an estimated aggregate of $45,985.31 across this reporting matrix range.

Provider Avg Cost Per Claim

$1,149.63

State Avg Cost Per Claim

$965.31

Note on Expenses: These indicators represent gross infrastructure resource tracking paid directly to supply pharmacy networks by Medicare Part D configurations. These calculations do not track individual patient insurance tier copays or out-of-pocket shelf prices at retail checkout lanes.

Clinical Summary

A morpholine and thiophene derivative that functions as a FACTOR XA INHIBITOR and is used in the treatment and prevention of DEEP-VEIN THROMBOSIS and PULMONARY EMBOLISM. It is also used for the prevention of STROKE and systemic embolization in patients with non-valvular ATRIAL FIBRILLATION, and for the prevention of atherothrombotic events in patients after an ACUTE CORONARY SYNDROME.

Therapeutic Applications

Rivaroxaban is used to prevent blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip or knee replacement surgery. It is also used to prevent blood clots from forming in high-risk patients with limited mobility during their hospital stay and after discharge. In addition, rivaroxaban is used to treat blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE) and to prevent the blood clots from forming again. Rivaroxaban may be used in children to prevent blood clots from forming after a certain heart surgery (Fontan procedure). Rivaroxaban is an anticoagulant that works by blocking certain clotting proteins in your blood.

Dataset Methodology & CMS Source Information

This analytical profile maps public infrastructure records sourced directly from official **Centers for Medicare & Medicaid Services (CMS)** public data releases. The statistics above track documented pharmaceutical treatment trends assigned to beneficiaries specifically under federal public programs. Evaluating the prescriptive footprints of clinical practitioners like JOHN DAVID BISOGNANO MD provides transparency into local medical care patterns within Ann Arbor, MI.

Key Learning Objectives for this Profile:

  • Prescribing Frequencies: Track and evaluate the volume metrics of specific brand-name and generic medical formulas chosen by this provider over time.
  • Clinical Focus Areas: Identify how the provider distributes therapeutic selections across medical care options to gain insight into their true day-to-day **Cardiovascular Disease** practice concentrations.
  • Program Cost Awareness: Review the calculated total systemic drug costs and raw transactional volumes linked to these orders to better anticipate network insurance coverage structures.
  • Patient-Centered Evaluation: Cross-reference localized regional care comparisons to align practitioner habits directly with your proactive health maintenance goals.

Data Scope Exclusion & Limitations: The data elements presented above explicitly reflect prescription orders processed for Medicare beneficiaries during the year 2023. This informational profile does not aggregate prescription data for individuals utilizing private commercial health plans, state Medicaid coverage, or self-pay options. However, because medical decision-making remains highly consistent across clinical settings, this public registry provides a reliable proxy for understanding the general prescribing preferences and pharmaceutical care approach used by this provider.